SARM (SARM1) (NM_015077) Human Mass Spec Standard

CAT#: PH315903

SARM1 MS Standard C13 and N15-labeled recombinant protein (NP_055892)



  View other "SARM" proteins (1)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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经常一起买 (1)
Rabbit Polyclonal SARM Antibody
    • 100 ug

CNY 5,808.00

Specifications

Product Data
Description SARM1 MS Standard C13 and N15-labeled recombinant protein (NP_055892)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC215903
Predicted MW 79.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_055892
RefSeq Size 7001
RefSeq ORF 2172
Synonyms hSARM1; HsTIR; MyD88-5; SAMD2; SARM
Locus ID 23098
Cytogenetics 17q11.2
Summary Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury. Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death in response to stress. Regulates dendritic arborization through the MAPK4-JNK pathway. Involved in innate immune response. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38.[UniProtKB/Swiss-Prot Function]
Protein Families Druggable Genome
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