CD105 (ENG) (NM_000118) Human Mass Spec Standard

CAT#: PH321699

ENG MS Standard C13 and N15-labeled recombinant protein (NP_000109)



  View other "CD105" proteins (8)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description ENG MS Standard C13 and N15-labeled recombinant protein (NP_000109)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC221699
Predicted MW 67.78 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000109
RefSeq Size 3142
RefSeq ORF 1884
Synonyms END; HHT1; ORW1
Locus ID 2022
Cytogenetics 9q34.11
Summary This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
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