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GBE1 (NM_000158) Human Untagged Clone
CAT＃: SC320912
GBE1 (untagged)-Human glucan (1,4-alpha-), branching enzyme 1 (GBE1)
CNY 2,950.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | APBD; GBE; GSD4 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_000158.2
GCTCCTCCCCGCTGGCGGGGGGAGAAAGGGCAGGAGGCCTTCCGTCCCGGCTATAAAGGG
CCCCGGACCGCCGCGGCTCGCCTCGGCTTGCCTCGACACGCCTAGGCGCCCTCCGGCTCC GCCCTAGCCGCCGCGTCCCAGCTAGAGCTCCAGCGCCCGCTCAGGCCCCACTCGACCCTC TCGGGCCTCGGCTACTTGGACTGCGGCGGAATATGGCGGCTCCGATGACTCCCGCGGCTC GGCCCGAGGACTACGAGGCGGCGCTCAATGCCGCCCTGGCTGACGTGCCCGAACTGGCCA GACTCCTGGAGATCGACCCGTACTTGAAGCCCTACGCCGTGGACTTCCAGCGCAGGTATA AGCAGTTTAGCCAAATTTTGAAGAACATTGGAGAAAATGAAGGTGGTATTGATAAGTTTT CCAGAGGCTATGAATCATTTGGCGTCCACAGATGTGCTGATGGTGGTTTATACTGCAAAG AATGGGCCCCGGGAGCAGAAGGAGTTTTTCTTACTGGAGATTTTAATGGTTGGAATCCAT TTTCGTACCCATACAAAAAACTGGATTATGGAAAATGGGAGCTGTATATCCCACCAAAGC AGAATAAATCTGTACTCGTGCCTCATGGATCCAAATTAAAGGTAGTTATTACTAGTAAAA GCGGAGAGATCTTGTATCGTATTTCACCGTGGGCAAAGTATGTGGTTCGTGAAGGTGATA ATGTGAATTATGATTGGATACACTGGGATCCAGAACACTCATATGAGTTTAAGCATTCCA GACCAAAGAAGCCACGGAGTCTAAGAATTTATGAATCTCATGTGGGAATTTCTTCCCATG AAGGAAAAGTAGCTTCTTATAAACATTTTACATGCAATGTACTACCAAGAATCAAAGGCC TTGGATACAACTGCATTCAGTTGATGGCAATCATGGAGCATGCTTACTATGCCAGCTTTG GTTACCAAATCACAAGCTTCTTTGCAGCTTCCAGCCGTTATGGATCACCTGAAGAGCTAC AAGAACTGGTAGACACAGCTCATTCCATGGGTATCATAGTCCTCTTAGATGTGGTACACA GCCATGCTTCAAAAAATTCAGCAGATGGATTGAATATGTTTGATGGGACAGATTCCTGTT ATTTTCATTCTGGACCTAGAGGGACTCATGATCTTTGGGATAGCAGATTGTTTGCCTACT CCAGCTGGGAAGTTTTAAGATTCCTTCTGTCAAACATAAGATGGTGGTTGGAAGAATATC GCTTTGATGGATTTCGTTTTGATGGTGTTACGTCCATGCTTTATCATCACCATGGAGTGG GTCAAGGTTTCTCAGGTGATTACAGTGAATATTTCGGACTACAAGTAGATGAAGATGCCT TGACTTACCTCATGTTGGCAAATCATTTGGTTCACACGCTGTGTCCCGATTCTATAACAA TAGCTGAGGATGTATCAGGAATGCCAGCTCTGTGCTCTCCAATTTCCCAGGGAGGGGGTG GTTTTGACTATCGACTAGCCATGGCAATTCCAGATAAGTGGATTCAGCTACTTAAAGAGT TTAAAGATGAAGACTGGAACATGGGCGATATAGTATACACGCTCACAAACAGGCGCTACC TTGAAAAGTGCATTGCTTATGCAGAGAGCCATGATCAGGCATTGGTTGGGGATAAGTCGC TGGCATTTTGGTTGATGGATGCCGAAATGTATACAAACATGAGTGTCCTGACTCCTTTTA CTCCAGTTATTGATCGTGGAATACAGCTTCATAAAATGATTCGACTCATTACGCATGGGC TTGGTGGAGAAGGCTATCTCAATTTCATGGGTAATGAATTTGGGCATCCTGAATGGTTAG ACTTCCCAAGAAAAGGAAATAATGAGAGTTACCATTATGCCAGGCGGCAGTTTCATTTAA CTGACGACGACCTTCTTCGCTACAAGTTCCTAAATAATTTTGACAGGGATATGAATAGAT TGGAAGAAAGATATGGTTGGCTTGCAGCTCCACAGGCCTACGTGAGTGAAAAACATGAAG GCAATAAGATCATTGCTTTTGAAAGAGCAGGTCTTCTTTTCATTTTCAACTTCCATCCAA GCAAGAGCTACACTGACTACCGAGTTGGAACAGCATTGCCAGGGAAATTCAAAATTGTGC TAGATTCAGATGCAGCGGAATATGGAGGGCATCAGAGACTGGACCACAGCACTGACTTTT TTTCTGAGGCTTTTGAACATAATGGGCGTCCCTATTCTCTTTTGGTGTACATTCCAAGCA GAGTGGCCCTCATCCTTCAGAATGTGGATCTGCCGAATTGAAGAGGCCTGATTTCAGCTC CACCAGATGCAGATTTGTGTTTTGTTTTCTTGTTATCACTGTCACACAGCTTATAACATG TATGCTTTTCAGAATACAGTTGTCTAGCCAAGCCATCAAGTGTCTGAAATTCAATATTGG TTTATGCAAATACAGCAAACTTTTATTTAAGTAGATAGGAGAATATGTTTAAAATATTAG GAATCCTAGACCATATTTTCAAGTCATCTTAGCAGCTAGGATTCTCAAATGGAAGTGTTA TATATAATATGTTAAAAACATTTTGCTTTCCTGGCTAATTATTTGATCCTTTTAAATTCA AATTTGAATCATTTGTCATGTATGATTATTTCTGTTAAATGTACACAGTATTTAAGATGG ATATTTGGTGGCTCTATTTGTTCTGATATCTTTTGGTCTAAATTATGAGGTACCAAGATT GTTTCTTTGTTTCTTTTTTTCAAATTGTGTTTAGAAATACTGTAATAAATATGCAGTAGT GATATAAAGAATTATATCCAAGGTAATATAAAAGCCATTACGTATGAACTCAAAAAAAAA AAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_000158 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000158.2, NP_000149.2 |
| RefSeq Size | 3099 bp |
| RefSeq ORF | 2109 bp |
| Locus ID | 2632 |
| UniProt ID | Q04446 |
| Domains | isoamylase_N, alpha-amylase, Aamy |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Starch and sucrose metabolism |
| Gene Summary | The protein encoded by this gene is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease). [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Systemic Correction of Murine Glycogen Storage Disease Type IV by an AAV-Mediated Gene Therapy
,Yi, H;Zhang, Q;Brooks, ED;Yang, C;Thurberg, BL;Kishnani, PS;Sun, B;,
Hum. Gene Ther.
,PubMed ID 27832700
[GBE1]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204152 | GBE1 (Myc-DDK-tagged)-Human glucan (1,4-alpha-), branching enzyme 1 (GBE1) |
CNY 5,144.00 |
|
| RC204152L3 | Lenti ORF clone of Human glucan (1,4-alpha-), branching enzyme 1 (GBE1), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC204152L4 | Lenti ORF clone of Human glucan (1,4-alpha-), branching enzyme 1 (GBE1), mGFP tagged |
CNY 7,700.00 |
|
| RG204152 | GBE1 (tGFP-tagged) - Human glucan (1,4-alpha-), branching enzyme 1 (GBE1) |
CNY 6,370.00 |
|
| SC120081 | GBE1 (untagged)-Human glucan (1,4-alpha-), branching enzyme 1 (GBE1) |
CNY 2,950.00 |
