C3AR1 Mouse Monoclonal Antibody [Clone ID: hC3aRZ1]

Specifications

Product Data
Clone Name	hC3aRZ1
Applications	FC, IHC
Recommend Dilution	Immunohistochemistry on frozen sections. Flow Cytometry: 1/10 - 1/20.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human C3aR protein
Specificity	This antibody recognises the receptor for complement component C3a (C3aR).
Formulation	Phosphate buffered saline pH7.4 containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	complement component 3a receptor 1
Database Link	Entrez Gene 719 Human UniProt ID Q16581
Background	C3a is a 55kD cell surface protein of the rhodopsin family of G protein-coupled seven-transmembrane receptors. C3a is an anaphylatoxin, which is a potent proinflammatory mediator that possesses immunoregulatory properties. C3a regulates inflammatory functions by binding to the C3a receptor. C3aR is expressed on various tissues and leucocytes including basophils, neutrophils, mast cells, eosinophils and activated T lymphocytes. Expression levels of C3aR on human cells varies significantly between donors.
Synonyms	C3a-R, C3AR, C3AR1, AZ3B, C3R1, HNFAG09
Reference Data

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