Nkx2.5 (NKX2-5) Mouse Monoclonal Antibody [Clone ID: 2E1]

Specifications

Product Data
Clone Name	2E1
Applications	ELISA, WB
Recommend Dilution	Western Blot: 1/500 - 1/2000. ELISA: 1/10000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human NKX2.5 expressed in E. Coli.
Specificity	This antibody reacts to NKX2.5
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0,03% sodium azide
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	35 kDa
Gene Name	NK2 homeobox 5
Database Link	Entrez Gene 1482 Human UniProt ID P52952
Background	NKX2.5: NK2 transcription factor related, locus 5 (Drosophila), also known as CSX. It is a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.
Synonyms	CSX, NKX2.5, NKX2E
Reference Data

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