Tuberin (TSC2) Rabbit Polyclonal Antibody

CAT#: AP21007PU-N

Tuberin (TSC2) rabbit polyclonal antibody, Aff - Purified



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CNY 4873.00


货期*
10周

规格
    • 100 ug

Cited in 1 publication.

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Specifications

Product Data
Applications IHC
Recommend Dilution Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids 1400-1500 of Human Tuberin.
Specificity This antibody detects endogenous levels of Tsc2 protein.
(region surrounding Ala1468)
Formulation PBS, pH 7.2
State: Aff - Purified
State: Liquid purified Ig fraction (> 95% by SDS-PAGE)
Preservative: 0.05% Sodium Azide
Concentration 1.0 mg/ml
Purification Immunoaffinity Chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Predicted Protein Size ~ 200 kDa
Gene Name tuberous sclerosis 2
Background TSC2 is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. It may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Mutations in TSC2 lead to tuberous sclerosis complex.
Synonyms Tuberous sclerosis 2 protein, TSC4
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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