CHMP6 (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	This antibody is suitable for Western blotting. The suggested dilution is: 1/100-1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 1-30aa) of human CHMP6.
Specificity	This antibody detects human CHMP6 at N-term.
Isotype	Ig
Formulation	PBS with 0.09% (W/V) Sodium Azide. State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Purified through a protein A column; followed by peptide affinity purification.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	charged multivesicular body protein 6
Database Link	Entrez Gene 79643 Human UniProt ID Q96FZ7
Background	CHMP6 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PMID 16730941]).
Synonyms	VPS20
Note	Molecular Weight: 23485 Da
Reference Data
Protein Pathways	Endocytosis

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