Periostin (POSTN) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Western Blot: ~ 1/1000. Immunofluorescence: 1/10-1/50. Flow Cytometry: 1/25. Immunohistochemistry on Paraffin Sections: 1/10-1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 687-716 amino acids from the C-terminal region of human Periostin.
Specificity	This antibody recognizes Human Periostin (C-term). Cellular Location: Golgi apparatus Tissue Location: Widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus, thyroid tissue and breast. Up-regulated in epithelial ovarian tumors; not expressed in normal ovaries. Also highly expressed at the tumor periphery of lung carcinoma tissue but not within the tumor. Overexpressed in breast cancers.
Isotype	Ig
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A chromatogrphy, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	periostin
Database Link	Entrez Gene 10631 Human UniProt ID Q15063
Background	POSTN binds to heparin. It induces cell attachment and spreading and plays a role in cell adhesion and may play a role in extracellular matrix mineralization.
Synonyms	POSTN, OSF2, OSF-2, PN
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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