KIR2DL3 Mouse Monoclonal Antibody [Clone ID: 190IIC311]

Specifications

Product Data
Clone Name	190IIC311
Applications	ELISA, FC, ICC/IF, WB
Recommend Dilution	Flow Cytometry (5-10g/1x10e6). ELISA (1/1,000 when tested against the immunizing protein). Western blot (1 µg/ml). The antibody has been tested by ELISA, Western blot and immunofluorescent staining with Flow Cytometric analysis to assure specificity. This product is routinely tested on peripheral blood mononuclear cells (PBMCs) or natural Killer(NK) cells. The histogram is an example of the expected reactivity.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human KIR2DL3 (19-161aa) purified from E. coli
Specificity	Reacts with extracellular domain of the KIR2DL3. Shows no reactivity with KIR2DL1 and KIR2DS4 in Western blot and ELISA.
Isotype	IgG2a, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
Database Link	NP_055326 Entrez Gene 3804 Human UniProt ID P43628
Background	Reacts with extracellular domain of the KIR2DL3, a member of the Killer cell immunoglobulin-liKe receptor(KIR) family. The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on human NK cells and a subset of human T cells which they are involved in recognition of either MHC class I molecules or unKnown ligand on target cells and inhibit cytotoxic activities.
Synonyms	Killer cell immunoglobulin like receptor, Two Ig domains and long cytoplasmic tail 3, Killer cell immunoglobulin-like receptor 2DL3, CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, NKAT2a, NKAT2b, Natural killer-associated transcript 2, NKAT-2, p58 natural killer cell receptor clone CL-6, p58 NK receptor CL-6, p58.2 MHC class-I-specific NK receptor, CD158B2, KIRCL23, p58
Reference Data

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