CRMP2 (DPYSL2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-300 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 476-493 amino acids of Human dihydropyrimidinase-like 2
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	dihydropyrimidinase like 2
Database Link	NP_001377 Entrez Gene 12934 MouseEntrez Gene 25416 RatEntrez Gene 1808 Human UniProt ID Q16555
Background	This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance; growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse; and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders; and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms	CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Axon guidance

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