PRKAR1B Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm, Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 50-62 amino acids of Human protein kinase, cAMP-dependent, regulatory, type I, beta
Isotype	IgG
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	protein kinase cAMP-dependent type I regulatory subunit beta
Database Link	NP_002726 Entrez Gene 19085 MouseEntrez Gene 25521 RatEntrez Gene 5575 Human UniProt ID P31321
Background	Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins; PKA controls many biochemical events in the cell including regulation of metabolism; ion transport; and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.
Synonyms	PRKAR1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Apoptosis, Insulin signaling pathway

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