Gria1 Mouse Monoclonal Antibody [Clone ID: S355-1]

Specifications

Product Data
Clone Name	S355-1
Recommend Dilution	WB: 1:1000
Reactivity	Rat, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1
Formulation	PBS pH7.4, 50% glycerol, 0.1% sodium azide
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	glutamate ionotropic receptor AMPA type subunit 1
Database Link	NP_113796 Entrez Gene 14799 MouseEntrez Gene 50592 Rat UniProt ID P19490
Background	Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists . GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration .
Synonyms	GluA1; GLUH1; GluR-A; gluR-A; GLUR1; GLURA; GluRA; HBGR1; HIPA1
Note	Detects ~100kDa. Does not cross-react with GluR2.
Reference Data

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