PGP9.5 (UCHL1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, ICC/IF, WB
Recommend Dilution	WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Formulation	Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	25kDa
Gene Name	ubiquitin C-terminal hydrolase L1
Database Link	NP_004172 Entrez Gene 22223 MouseEntrez Gene 29545 RatEntrez Gene 7345 Human UniProt ID P09936
Background	The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.
Synonyms	HEL-117; NDGOA; PARK5; PGP 9.5; PGP9.5; PGP95; Uch-L1
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Parkinson's disease

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