GEFT (ARHGEF25) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-ARHGEF25antibody: synthetic peptide directed towards the C terminal of human GEFT. Synthetic peptide located within the following region: RLGDQAQGSTHTPINGSLPSLLLSPKGEVARALLPLDKQALGDIPQAPHD
Isotype	IgG
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	64 kDa
Gene Name	Rho guanine nucleotide exchange factor 25
Database Link	NP_891992 Entrez Gene 115557 Human UniProt ID Q86VW2
Background	The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange.The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange (Souchet et al., 2002 [PubMed 11861769]). [supplied by OMIM]
Synonyms	GEFT; p63RhoGEF
Note	Immunogen Sequence Homology: Pig: 100%; Human: 100%; Rat: 92%; Bovine: 92%; Dog: 85%; Horse: 85%; Mouse: 85%; Rabbit: 85%; Guinea pig: 85%
Reference Data

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