BCKDH kinase (BCKDK) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-BCKD Antibody: A synthesized peptide derived from human BCKD
Isotype	IgG
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	46 kDa
Gene Name	branched chain ketoacid dehydrogenase kinase
Database Link	NP_005872 Entrez Gene 12041 MouseEntrez Gene 29603 RatEntrez Gene 10295 Human UniProt ID O14874
Background	BCKDK an atypical protein kinase associated with the mitochondrial matrix. Contains a HATPase_c domain, found in several ATP-binding proteins including protein histidine kinases (PHKs), PHDKs, DNA gyrase B, topoisomerases, heat shock proteins, and DNA mismatch repair proteins. Unlike PHKs, BCK dimerizes through direct interaction of two opposing nucleotide-binding domains.
Synonyms	BCKDKD; BDK
Note	BCKD antibody detects endogenous levels of total BCKD
Reference Data
Protein Families	Druggable Genome, Protein Kinase

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