p73 (TP73) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-p73 Antibody: A synthesized peptide derived from human p73
Isotype	IgG
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	80 kDa
Gene Name	tumor protein p73
Database Link	NP_005418 Entrez Gene 7161 Human UniProt ID O15350
Background	p73 a protein of the p53 family of proteins. p73, like p53, may have tumor suppressor activity, but its multiple isoforms possess different and sometimes opposing functions. Participates in the apoptotic response to DNA damage. Phosphorylated in a cell cycle-dependent manner and negatively regulated by CDKs.
Synonyms	P73
Note	p73 antibody detects endogenous levels of total p73
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Neurotrophin signaling pathway, p53 signaling pathway

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