Vasopressin V1b receptor (AVPR1B) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 1-5 µg/ml FC Not tested
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to the extracellular domain of V1b vasopressin receptor. This sequence is identical to human, mouse and rat.
Isotype	IgG
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	~50 kDa
Gene Name	arginine vasopressin receptor 1B
Database Link	NP_000698 Entrez Gene 553 Human UniProt ID P47901
Background	The vasopressin r V1B eceptor V1bR is a member of the Vasopressin/Oxytocin G-protein coupled receptors family . The V1B receptor is expressed specifically in pituitary corticotropes and mediates the stimulatory effect of vasopressin on ACTH release. Vasopressin V1B receptor expression has been documented in the pituitary, pituitary tumors, pheochromocytoma, breast cancer, and small-cell lung carcinomas.
Synonyms	AVPR3
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Calcium signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction

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