HTRA1 Rabbit Polyclonal Antibody
CNY 4628.00
Cited in 1 publication. |
CNY 300.00
CNY 1430.00
CNY 2900.00
CNY 6650.00
Specifications
Product Data | |
Applications | WB |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human HTRA1 |
Specificity | Expected reactivity: Human |
Formulation | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers. |
Concentration | lot specific |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage Condition | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Predicted Protein Size | 52 kDa |
Gene Name | HtrA serine peptidase 1 |
Database Link | |
Background | This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. |
Synonyms | ARMD7; HTRA; IGFBP5-protease; L56; ORF480; PRSS11 |
Reference Data | |
Protein Families | Druggable Genome, Protease, Secreted Protein |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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β-Amyloid induces nuclear protease-mediated lamin fragmentation independent of caspase activation.
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Biochimica et biophysica acta
,PubMed ID 26876308
[HTRA1]
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