WAVE 1 (WASF1) Rabbit Monoclonal Antibody [Clone ID: R03-5K1]

Specifications

Product Data
Clone Name	R03-5K1
Applications	WB
Recommend Dilution	WB: 1/1000-1/5000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant protein of human WAVE 1
Isotype	IgG
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 62 kDa; Observed MW: 90 kDa
Gene Name	WAS protein family member 1
Database Link	Entrez Gene 8936 Human UniProt ID Q92558
Background	Swiss-Prot Acc.Q92558.Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex . As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes .
Synonyms	FLJ31482; KIAA0269; OTTHUMP00000016990; SCAR1; WAVE; WAVE1
Reference Data

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