Cd4 Rat Monoclonal Antibody [Clone ID: GK1.5]
CAT#: TA420138
Cd4 rat monoclonal antibody, clone GK1.5, ALEXA FLUOR® 488,ALEXA FLUOR® 647,FITC,Low Endotoxin,Purified,RPE
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CNY 8040.00
货期*
4周
规格
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Specifications
Product Data | |
Clone Name | GK1.5 |
Applications | ELISA, FC, IF, IHC, IP, WB |
Host | Rat |
Clonality | Monoclonal |
Immunogen | Murine CD4. |
Specificity | CD4 |
Isotype | IgG2b |
Formulation | Phosphate buffered saline containing 0.09%Sodium Azide Label: ALEXA FLUOR® 488,ALEXA FLUOR® 647,FITC,Low Endotoxin,Purified,RPE State: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant Purified IgG - liquid |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | +4°C, -20°C if preferred |
Gene Name | CD4 antigen |
Database Link | |
Background | Rat anti Mouse CD4 antibody, clone GK1.5 recognizes mouse CD4, a ~55 kDa protein also known as Ly-4 and L3T4. CD4 is a single chain transmembraneous glycoprotein which belongs to the immunoglobulin superfamily, and is primarily expressed on T helper cells, peripheral blood monocytes and tissue macrophages. CD4 is also expressed on a subpopulation of regulatory T cells (CD4+ CD25+), which play a key role in the maintenance of self tolerance. Rat anti Mouse CD4 antibody, clone GK1.5 has been reported to block CD4+ T-cell activation. It blocks class II MHC antigen-specific binding, thereby inhibiting functions such as class II MHC antigen-specific proliferation and the release of lymphokines. It may also be used for in vivo and in vitro cell depletion of CD4+ T-cells. |
Synonyms | L3T4 ANTIGEN,LY-4 |
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