Non Neuronal Enolase (ENO1) Rabbit Monoclonal Antibody [Clone ID: OTIR4G3]

Specifications

Product Data
Clone Name	OTIR4G3
Applications	WB
Recommend Dilution	WB1:2000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment of Human ENO1 (NP_001419) produced in Ecoli.
Isotype	IgG
Formulation	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
Predicted Protein Size	47.2KD
Gene Name	enolase 1
Database Link	NP_001419 Entrez Gene 13806 MouseEntrez Gene 2023 Human UniProt ID P06733
Background	This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011]
Synonyms	ENO1L1; HEL-S-17; MPB1; NNE; PPH
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Glycolysis / Gluconeogenesis, Metabolic pathways, RNA degradation

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