KIAA1731 (CEP295) (NM_033395) Human 3' UTR Clone

Specifications

Product Data
Product Name	KIAA1731 (CEP295) (NM_033395) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	KIAA1731
ACCN	NM_033395
Insert Size	119 bp
Sequence Data	Insert Sequence (showhide) >SC200438 3’UTR clone of NM_033395 The sequence shown below is from the reference sequence of NM_033395. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGAAACTTCGAGCCAAAAATACATGCTGACTTTCTAGAAATAGTGTAAAGGTTTTTTAATTGTGTATA TGTAGCATTAGACAAAATTATTTAAAGTCAATAAATTGTTATTCGAGGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_033395.2
Synonyms	KIAA1731
Summary	Centriole-enriched microtubule-binding protein involved in centriole biogenesis (PubMed:20844083, PubMed:25131205, PubMed:27185865). Essential for the generation of the distal portion of new-born centrioles in a CENPJ- and CEP120-mediated elongation dependent manner during the cell cycle S/G2 phase after formation of the initiating cartwheel structure (PubMed:27185865). Required for the recruitment of centriolar proteins, such as POC1B, POC5 and CEP135, into the distal portion of centrioles (PubMed:27185865). Also required for centriole-to-centrosome conversion during mitotic progression, but is dispensable for cartwheel removal or centriole disengagement (PubMed:25131205). Binds to and stabilizes centriolar microtubule (PubMed:27185865).[UniProtKB/Swiss-Prot Function]
Locus ID	85459
MW	4.6

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