Acid sphingomyelinase (SMPD1) (NM_000543) Human 3' UTR Clone

Specifications

Product Data
Product Name	Acid sphingomyelinase (SMPD1) (NM_000543) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ASM; ASMASE; NPD
ACCN	NM_000543
Insert Size	419 bp
Sequence Data	Insert Sequence (showhide) >SC205418 3’UTR clone of NM_000543 The sequence shown below is from the reference sequence of NM_000543. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGCCTGTGGCCAAGGCCACTGTTTTGCTAGGGCCCCAGGGCCCACATTTGGGAAAGTTCTTGATGTAGG AAAGGGTGAAAAAGCCCAAATGCTGCTGTGGTTCAACCAGGCAAGATCATCCGGTGAAAGAACCAGTCC CTGGGCCCCAAGGATGCCGGGGAAACAGGACCTTCTCCTTTCCTGGAGCTGGTTTAGCTGGATATGGGA GGGGGTTTGGCTGCCTGTGCCCAGGAGCTAGACTGCCTTGAGGCTGCTGTCCTTTCACAGCCATGGAGT AGAGGCCTAAGTTGACACTGCCCTGGGCAGACAAGACAGGAGCTGTCGCCCCAGGCCTGTGCTGCCCAG CCAGGAACCCTGTACTGCTGCTGCGACCTGATGCTGCCAGTCTGTTAAAATAAAGATAAGAGACTTGGA CTCCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000543.5
Synonyms	ASM; ASMASE; NPD
Summary	The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]
Locus ID	6609
MW	14.9

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