Cellular Apoptosis Susceptibility (CSE1L) (NM_001316) Human 3' UTR Clone

Specifications

Product Data
Product Name	Cellular Apoptosis Susceptibility (CSE1L) (NM_001316) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CAS; CSE1; XPO2
ACCN	NM_001316
Insert Size	541 bp
Sequence Data	Insert Sequence (showhide) >SC207113 3’UTR clone of NM_001316 The sequence shown below is from the reference sequence of NM_001316. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTTCAGGCAGCCAGTGTGACACTGCTTTAAACTGCATTTTTCTAATGGGCTAAACCCAGATGGTTTCCT AGGAAATCACAGGCTTCTGAGCACAGCTGCATTAAAACAAAGGAAGTTCTCCTTTTGAACTTGTCACGA ATTCCATCTTGTAAAGGATATTAAATGTTGCTTTAACCTGAACCTTGAGCAAATTAGTTGGTTTGTGTG ATCATACAGTTATGTGGGTGGCTTCTAGTTTGCAACTTCAAGGGACAAGTATTAATAGTTCAGTGTATG GCGTTGGTTTGTGTTGAGCGTTTGCACGGTTTGGATAATCTTAAATTTTGACGGACACTGTGGAGACTT TCTGTTACTAAATCCTTTTGTTTTGAAGCTGTTGCTATTTGTATTTCTCTTGTCCTTTATATTTTTTGT CTGTTTATTTACGCTTTTATTGGAAATGTGAATAAGTAAAGAATTACTTGTGTTACTTGCCAAGCAGTG CACATTTCATAGTTTCAAATCTGTAATCAGCAATAAAAATCCTAAAATATGTACCTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001316.4
Synonyms	CAS; CSE1; XPO2
Summary	Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Locus ID	1434
MW	20.6

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