CYRIB (NM_016623) Human 3' UTR Clone

Specifications

Product Data
Product Name	CYRIB (NM_016623) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BM-009; CYRI; CYRI-B; FAM49B; L1
ACCN	NM_016623
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC209006 3’UTR clone of NM_016623 The sequence shown below is from the reference sequence of NM_016623. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCCAAGCAAATTAAATCCATGCTGCAATAACAATTCTGGAATAAGCACCTGCTGTAGACAGAAGACAGT ATTCTGCAATGACTGAGAATGCAGTTTTTTAGTGATTGCAATTACTATCTCATTTATTCTTGCTTTTAT TTCTTTCCTCTGTTCCTCTTCCCTCTTTTTTAATCATGTTCTTAAGACTTCTTTTCTGTGCCAAAATCA GTAAAGTTACACTCTGAAGGGATATCATCCTTTCAAACGGGCCATCTAAGGCAGCTAATTATGCATTGC ATTGGGGTCTCTACTGAGAAAAATTCTGTGACTTGAACTAAATATTTTTAAATGTGGATTTTTTTTGAA ACTAATATTTAATATTGCTTCTCCTGCATGGCAAAACTGCCTATTCTGCTATTTAAAAACCCTCAATGA CTTTATTTTCTACTGCCGCCTTTTTCATGTGCAACCAAAATGAAAATGTTTAAATTAACTGTGTTGTAC AAATGGTACCCAACACAAACTTTTTTTAAATTAGTAATACTTTTGTTTAAAGTTTTAAGTTTGCATTTT GACTTTTTTTGTAAGGATGTATGTTGTGTGTTTAACCTTTATTAACTAACGTTAAAAGCTGTGATGTGT GCGTAGAATATTACGTATGCATGTTCATGTCTAAAGAATGGCTGTTGATGATAAAATAAAAATCAGCTT TCATTTTTCTAAGTGTGGCTTGGTTTACTGATGTTTTGTTTTTAGGCTTCTGAAGTTTTCCCCATGTAT GTTTTTATGGAATGCATATATACATTACATGATTTTTTCTTCTTTTAGGGGAGAGCCGGGTCTTTTCAT TAGAATTTTGATCATTGTCTATGTATATACTTTTAATTGCCTTTAAAATTTTGCTAAGTATATTAAGAC CAGTGATCTTTTCATTAACTGGACTTTTATTCTTGATTTACTCTTGTATGGATGTAGTAATGGAAGGAA AACCGCATCCTTGCTTGATTCTCCATTTCCAGGGGAGCGGGTAGCAACATGAAGGCAGAGTAGCCCTTT AATCATGGGAAGAGAGTGATTATAAGAGGGACTTCCCAGGAGAAAAGCAGAGGCCATGATCTCACTAGT GGTAGAAAACTAACAGGTTTCAGTTTAAGATCATAAAACCTAAATCATGAAATCTAAATCTCATGGTTG GAACAAACTACTTAAAGGTTGTCTAGTTCAACCATGCCAGTGTTTTAAATATTTAGGAATATCCGAGGT ATAATACAATTAAAATGTTTAACCATGGAAGAGAATCACAGAGGCTTCCATCAGACCCTTCTGGATTAA TAGGGCCAGATCATGGCACACACAGCTTCTCAAGATCACATCCCTGCTGATCTCTCTGGCCCTCCTGAT CACTGCTCCCCCACTTCACACCCTGTCCTGCAGCCAGGCCCTACTGCTTGCTGTTCACAAATTGTTCCA TGTGATGTCACTTCCTTAGCTCTGGTCTGGCTGGTCCCTGAACCTGACATTCCCTTCCTCCCCTTGTGA CCCTCTAATGAACGCCAACTTTCATCTTTGAAGGGTTAGCTTCTATTACCTCCTTCATGAAGCCTTCTG GATAACATTGGCCATATCCTTCTAGGCATCTTCTAAGAATAGTGTAATAGGCTGAATAGTGGCCCCCAG GAGATACATTCACTGGGAATCTCCACGTGTGACATTATTTGGAAAAAGTTTTTGCAGATGAAATCAAGG ACCTGGAAATGAGATCAACCTGTAGTAGGGTGGGCCCTAAATTCAATGACTAGCTCTTAGAAAAGAAGG GGAAATAGACACACAGAGCTGAAGGCCATGGGAAGATGGAGGCAGAGATTAGAGCAATGCATCTATGAG CCAAAGAACCCTAAGAATTGGAGGAAGTCACTAGAAGCTAGGAAAACAGGCATGTCACAGATTCTCCCT CAGAGTCTCGAGAAGGAACCAACCCTACCAATATCTTGATTTCAGACATCTGGCCTCCAGGATTGTGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_016623.5
Synonyms	BM-009; CYRI; CYRI-B; FAM49B; L1
Summary	Negatively regulates RAC1 signaling and RAC1-driven cytoskeletal remodeling (PubMed:31285585, PubMed:30250061). Regulates chemotaxis, cell migration and epithelial polarization by controlling the polarity, plasticity, duration and extent of protrusions. Limits Rac1 mediated activation of the Scar/WAVE complex, focuses protrusion signals and regulates pseudopod complexity by inhibiting Scar/WAVE-induced actin polymerization (PubMed:30250061). Protects against Salmonella bacterial infection. Attenuates processes such as macropinocytosis, phagocytosis and cell migration and restrict sopE-mediated bacterial entry (PubMed:31285585). Restricts also infection mediated by Mycobacterium tuberculosis and Listeria monocytogenes (By similarity). Involved in the regulation of mitochondrial dynamics and oxidative stress (PubMed:29059164).[UniProtKB/Swiss-Prot Function]
Locus ID	51571
MW	77.2

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