LRRC25 (NM_145256) Human 3' UTR Clone

Specifications

Product Data
Product Name	LRRC25 (NM_145256) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MAPA
ACCN	NM_145256
Insert Size	880 bp
Sequence Data	Insert Sequence (showhide) >SC210633 3’UTR clone of NM_145256 The sequence shown below is from the reference sequence of NM_145256. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAAGAGGAGTACGTGATCCCCGGGCACTGAGCCTAAGATGTCCTAACCTCCACCCAGAACCCCTTCAGT CCCTGCTGGGTGACTCAGGGCGTCCTAACGCCTCCATGGCCTCAGTTTCCCCATCTGAAGAATGGGTAC AGGAAAGGATTGTCCTTGAGGCCCCAGGAAGCTCTGCCGCCCCCTCCCTGTCCCTCATGCCGCTCCTCA GCTCCCTCAGCTCCTAGAGGGGGAAGAGGAGAGACCCCCAACAAGGGGACAGGACGGTCACTGTGCCAA TCCTGTCATCACCCTCCTGTGGATGTACAGGCAGTGCTCAATAAATGCTTCGAGGCTGATGAGGCTGCT GGCTCAGGGTGCGTGGGTTCCTCAAGGTGGGGATTTCTGAGTTCTAAGACCAAGTCTCCATCTGAGACT CCCAAATTGCTCCCCACCTCCCATCCCTGTTTTTTTTTGTTGTTGTTGTTTGTTTGTTTGTTTTTGAAA CTGAGTGTCACTCTGTCACCCAGGCTGGAGTGCAATGCTGCGGTCTCAGCTCACTGCAACCTCCGCCTC CTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGCACCCGCCACCATGCCG AGCTAATTTTTGTATTTATAATAGAGATGGGGTTTCGCCATGTTGGCCAGGCTGGTCTCGAACTCCTGA CCTCAAGCGATCTGCCCGCCTCGGCCTCCTGAAGTGCTGGGATTACAGGCGTGGCCACTGCGCCCAGGC ACATTCCTCCCTTCTGCCCCTCTCAGGGCCCCTTCCCAGGTCCCTGATCTCCAGGCTTGGCCTCCAGAG CAGCCCACACCAACCCCAAAATAAAAAAATGTATATATTCCTTTAGCTCTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_145256.3
Synonyms	MAPA
Summary	Plays a role in the inhibition of RLR-mediated type I interferon signaling pathway by targeting DDX58/RIG-I for autophagic degradation. Interacts specifically with ISG15-associated DDX58 to promote interaction between DDX58 and the autophagic cargo receptor p62/SQSTM1 to mediate DDX58 degradation via selective autophagy (PubMed:29288164). Plays also a role in the inhibition of NF-kappa-B signaling pathway and inflammatory response by promoting the degradation of p65/RELA.[UniProtKB/Swiss-Prot Function]
Locus ID	126364
MW	31.5

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.