GCSH (NM_004483) Human 3' UTR Clone

Specifications

Product Data
Product Name	GCSH (NM_004483) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	GCE; NKH
ACCN	NM_004483
Insert Size	951 bp
Sequence Data	Insert Sequence (showhide) >SC211089 3’UTR clone of NM_004483 The sequence shown below is from the reference sequence of NM_004483. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGAAATACATAAAATCTATTGAGGAGTGAAAATGGAACTCCTAAATAAACTAGTATGAAATAACGCAA GCCAGCAGAGTTGTCTTAAATTAGTGGTGGATAGAAGACTTAGAATAGAAACTTTTAGTATTACCGATG GGGAAAAAAAAACTACTGTTAACACTGCTAATGAAAGAAAATGCCCTTTAACTTTCTAATGATTATAGA TAAATATAATATGCGTCTTTTTCACAATATCCTATGATTTTTAGACTAGGCTCTAGTGTTCAGAATTCA TGAAATTATCCATGGTAAAAACTAGTTATAAAAATTACATAATTCAAAGATAACATTGTTATTCTTAAG CCTTATATAATATTGTAACTTGCATGTATCCATACCTGGATTTGGGATGAAATACTTAATGATCTTTCC ATTGGAAATAACTGGAAGTGAAGAGGTTTTGTTGCTTGTACAGTGTCAGATGAGGAACACCACTATCTT AATTTTGCGATACACTGCATTTGCTGGTGCTATTTTTATACAGTGAAGCAACAGCTTTGCAGCAAAATA ATAAAATACTTCTTCGTTAATCATGTTTGTTTTGATGTTAATATTTCATTTAGTAACTCTGCTAGTATT TGTGAAAGTGCTAACTTTAACTTACGGAAAGTTACTTTTTAAAAGGAAATTTAAGCCAGAACAATGCAA AGCTCCAAGAAAATGTTTTCTTTAGTCACAAATCTGGTTTTTCTTAAGCCAAGATCTGTCACCTTTAAC ATAATAAAAAATAAATCACCAACTTTGATTTTCTATCATGCGAGGTCTGAAGAAAGAAGAGGAAAGACA GAGGAAGGTGGAAGTTTTGATCAGTATAGCACATGGTGTTTTTAAGTTGTTAAACCACGTTCAGGTTTC CACTTAAGTCATGGGAATAAAAGTGGACAAGGACTGAAGCTTTATGAGCTCAGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004483.5
Synonyms	GCE; NKH
Summary	Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.[provided by RefSeq, Jan 2010]
Locus ID	2653
MW	37.2

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