PATZ1 (NM_032050) Human 3' UTR Clone

CAT#: SC212337

3' UTR clone of POZ (BTB) and AT hook containing zinc finger 1 (PATZ1) transcript variant 2 for miRNA target validation



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CNY 4845.00


货期*
3周

规格
    • 10 ug

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DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1280.00

Specifications

Product Data
Product Name PATZ1 (NM_032050) Human 3' UTR Clone
Vector pMirTarget
Synonyms dJ400N23; MAZR; PATZ; RIAZ; ZBTB19; ZNF278; ZSG
ACCN NM_032050
Insert Size 1117 bp
Sequence Data
>SC212337 3’UTR clone of NM_032050
The sequence shown below is from the reference sequence of NM_032050. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
CAGCAGCCCATGGGGCCTGAAGGGAAATGAGGCAGCTGCTGTGTCCCCACGGAAACAACCATCTGGGGA
CTGCTGGGAAATGCTGTGAATGCGGAGGGAAGTGATGTTTGGGTTCTGTAGCTGAGAGATTTTTATTCA
TTTTTAACTGCCCCCCAACCCCACTCCAACTCCTTCTCCACCACCCATTCTCCCAATGGTCTTTAGAAA
TAGATTTTCATCTGATATTCTGCAGAAATATCAATGAGACTTGGTATGGGACAGGGGCAGAAAACACTA
CATAGGCCTCCAAGGCAAAACCAGTCCCAGTTTCTTTAATGGGAAGAAGCTGGAATTCCTGGTGCTCAA
TTCTTAGTGACCCCAATCCTATACCCAAATCTATGATATTCTGGGACCTCAGTGATTTTGGTCCCCTCC
CACTTCTCTAGTTCGTCATCCTCCCTTCCCATATCCTTCAAAAGAACCACACTAGGGTCTCCACCTACT
TATACAATGCGGATGCCCAACTGTTTTTAAGGAAGCCAGAAGCATCCCATGGACCATGGGGTGAGTGTC
CTCCAAGAGCCCCCTGAGCTCAGCCCTCTGCCTGGAGGGCTCCAGACCTTTCTGAGCCCTGCTTGGAGG
CGAGCATTTTCACTGCTAGGACAAGCTCAGCTGTTGAGGACACCCCCACCCCAAATTTCAGTTCTTACG
TGATTTTAACCATTCAACATGCTGTTGGGTTTTAATTCTCTAATTATTATTATTATTGTTATTATTTTT
TAGGACCAGTTGTAGTGAATTGCTACTGAAAGCTATCCCAGGTGATACAGAGCTCTTTGTAAACCGCAG
TCACACATTAGGGTTAGTATTAAACTTTGTTTAGATGTACCATAATTAACTTGGCTAGTTGATTGTTTG
AAGTCTATGGAAGAAATAGTTTTATGCAAAATTTTAAAAAATGCCAGTCTGGTCAGGGAAGTAGGGGGT
TTCAATGCTGTTGGGAACCAGGAAGGTGGGACAGCCGGCAGGTAGGGACATTGTGTACCTCAGTTGTGT
CACATGTGAGCAAGCCCAGGTTGACCTTGTGATGTGAATTGATCTGATCAGACTGTATTAAAAATGTTA
GTACATTACTCTA
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_032050.2
Synonyms dJ400N23; MAZR; PATZ; RIAZ; ZBTB19; ZNF278; ZSG
Summary The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq, Jul 2008]
Locus ID 23598
MW 40.9
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