RCC1 (NM_001048199) Human 3' UTR Clone

Specifications

Product Data
Product Name	RCC1 (NM_001048199) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CHC1; RCC1-I; SNHG3-RCC1
ACCN	NM_001048199
Insert Size	1012 bp
Sequence Data	Insert Sequence (showhide) >SC213040 3’UTR clone of NM_001048199 The sequence shown below is from the reference sequence of NM_001048199. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTATTAGTCAAGGACAAAGAACAGAGCTGATGAAGCCTCTGAGGGCCTGGCTTCTGTCCTGCACAACCT CCCTCACAGAACAGGGAAGCAGTGACAGCTGCAGATGGCAGCGGGCCTCTCCCCAGCCCTGAGCACTGT GTCAGTTCCTGCCTTTTCTCATCAGCAGAACAGAATCCTTTTCCTCTTTTCCTTCCTCCTCTTTGGAAT TTTCCTGGGACCTACAGAATAAAGGGGGGGATGGACAGGGGGTTTTCAAAAGGAACATGGCTCACTCAG AGCTATATGGTTAGACGTTTCTCCCCTTTTCCCTACCTTCCATGGTCCTGGTTGGCCCTGGCTTTGCCT ACTAGAAAACCAAAACTTCCCCCCTGGGGTTTTGTGCCCACTCTCTGAGAAGTTGGGGCTCCATCAAGC CCCATTCTAGTCATGTGCCCCTTTCCTGTCCCTAACAGTCCACAGGCAAACAAATGGTACAGTCATAAG AGCCATCTGTCACGGACCCACGCCCAGAGGAACGTGCAGAAAAAAGCAGAGCTACATGGCTGTGGGCAA CTATAAGCCAAATATTTGGCTCAGAACAGGTGTCCATGGGACAAAAAAGAACGATCCTCCACTTGACCA AGAAAAAAGTGATTCTCCCAGAAGCACAAAGCATACTCTTGCCCCTCAGGTGTTGCTTGTGTACATCGT ACCCATCCATTCGGCTTCACCTGCAGCCAACGGCCTGGAATCGCAAAGAGACACCACTCTGGGCAGAGC AGAGCAGGGTATGGGGTGGGGAGAGAGGGTGGAGGGTTTTATAAACAAACTTAACAGCAATATTGAAAG GAGGTGGGGGATTGAGGGAGGGACAGAGTGTTGGAGGGCCAGAGACTAGTCCTGAGATGGAAACAGCAA CTTGTACAGTGGCTGAGAAAATAGGATATAGTTTTGATTTTTTTAATTGTAAAATATTTTGGAGGGAGA ACAAAATCTTTTAACATTTTGAATAAATTTAGAGTTTTATAAAATA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001048199.3
Synonyms	CHC1; RCC1-I; SNHG3-RCC1
Summary	Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis (PubMed:1944575, PubMed:17435751, PubMed:20668449, PubMed:22215983, PubMed:11336674). Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis (PubMed:12194828, PubMed:17435751, PubMed:22215983). Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import (PubMed:22215983). Involved in the regulation of onset of chromosome condensation in the S phase (PubMed:3678831). Binds both to the nucleosomes and double-stranded DNA (PubMed:17435751, PubMed:18762580).[UniProtKB/Swiss-Prot Function]
Locus ID	1104
MW	38.1

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