Factor VII (F7) (NM_000131) Human 3' UTR Clone

Specifications

Product Data
Product Name	Factor VII (F7) (NM_000131) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	SPCA
ACCN	NM_000131
Insert Size	1719 bp
Sequence Data	Insert Sequence (showhide) >SC216011 3’UTR clone of NM_000131 The sequence shown below is from the reference sequence of NM_000131. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGAGTCCTCCTGCGAGCCCCATTTCCCTAGCCCAGCAGCCCTGGCCTGTGGAGAGAAAGCCAAGGCTGC GTCGAACTGTCCTGGCACCAAATCCCATATATTCTTCTGCAGTTAATGGGGTAGAGGAGGGCATGGGAG GGAGGGAGAGGTGGGGAGGGAGACAGAGACAGAAACAGAGAGAGACAGAGACAGAGAGAGACTGAGGGA GAGACTCTGAGGACATGGAGAGAGACTCAAAGAGACTCCAAGATTCAAAGAGACTAATAGAGACACAGA GATGGAATAGAAAAGATGAGAGGCAGAGGCAGACAGGCGCTGGACAGAGGGGCAGGGGAGTGCCAAGGT TGTCCTGGAGGCAGACAGCCCAGCTGAGCCTCCTTACCTCCCTTCAGCCAAGCCCACCTGCACGTGATC TGCTGGCCTCAGGCTGCTGCTCTGCCTTCATTGCTGGAGACAGTAGAGGCATGAACACACATGGATGCA CACACACACACGCCAATGCACACACACAGAGATATGCACACACACGGATGCACACACAGATGGTCACAC AGAGATACGCAAACACACCGATGCACACGCACATAGAGATATGCACACACAGATGCACACACAGATATA CACATGGATGCACGCACATGCCAATGCACGCACACATCAGTGCACACGGATGCACAGAGATATGCACAC ACCGATGTGCGCACACACAGATATGCACACACATGGATGAGCACACACACACCAATGCGCACACACACC GATGTACACACACAGATGCACACACAGATGCACACACACCGATGCTGACTCCATGTGTGCTGTCCTCTG AAGGCGGTTGTTTAGCTCTCACTTTTCTGGTTCTTATCCATTATCATCTTCACTTCAGACAATTCAGAA GCATCACCATGCATGGTGGCGAATGCCCCCAAACTCTCCCCCAAATGTATTTCTCCCTTCGCTGGGTGC CGGGCTGCACAGACTATTCCCCACCTGCTTCCCAGCTTCACAATAAACGGCTGCGTCTCCTCCGCACAC CTGTGGTGCCTGCCACCCACTGGGTTGCCCATGATTCATTTTTGGAGCCCCCGGTGCTCATCCTCTGAG ATGCTCTTTTCTTTCACAATTTTCAACATCACTGAAATGAACCCTCACATGGAAGCTATTTTTTAAAAA CAAAAGCTGTTTGATAGATGTTTGAGGCTGTAGCTCCCAGGATCCTGTGGAATTGGATGTTCTCTCCCT GCCACAGCCCTTGTCAATGATATTTCACAGAGACCCTGGGAGCACCTGCTCAAGAGTCAGGGACACACG CATCACTAAATGCAAGTTCCCAGGCCCTGGCTGCAGTGGGAGGACCTGGCAAGCTGCACTCTTGCTGAG TCCCCAGGGTGGTGGAAGAAGAATGAGAAACACATGAACAGAGAAATGGGGAGGTGACAAACAGTGCCC CCACTCAGACTCCGGCAAGCACGGCTCAGAGAGTGGACTCGATGCCATCCCTGCAGGGCCGTCCTGGGC ACCACTGGCACTCACAGCAGCAAGGTGGGCACCATTGGCACTCACAGCAGCAAGGCAGGCACCAGCAAC CCACCTCGGGGGCACTCAGGCATCATCTACTTCAGAGCAGACAGGGTCTATGAACTACAGCCGTGGGCT GCTTCCAAGGCACCCTGCTCTTGTAAATAAAGTTTTATGGGAACACAAAAAAAAAAAAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000131.4
Synonyms	SPCA
Summary	This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015]
Locus ID	2155
MW	65.3

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