ERO1L (ERO1A) (NM_014584) Human 3' UTR Clone

Specifications

Product Data
Product Name	ERO1L (ERO1A) (NM_014584) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ERO1-alpha; ERO1-L; ERO1-L-alpha; Ero1alpha; ERO1L; ERO1LA
ACCN	NM_014584
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC216082 3’UTR clone of NM_014584 The sequence shown below is from the reference sequence of NM_014584. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTCAGGAACTTGTTACAGAATATTCATTAAAGAAAACAAGCTGATATGTGCCTGTTTCTGGACAATGGA GGCGAAAGAGTGGAATTTCATTCAAAGGCATAATAGCAATGACAGTCTTAAGCCAAACATTTTATATAA AGTTGCTTTTGTAAAGGAGAATTATATTGTTTTAAGTAAACACATTTTTAAAAATTGTGTTAAGTCTAT GTATAATACTACTGTGAGTAAAAGTAATACTTTAATAATGTGGTACAAATTTTAAAGTTTAATATTGAA TAAAAGGAGGATTATCAAATTCATATATGATAAAAGTGAATGTTCTAAGTCTCTCAAACTAGCGTTTTA TGTAATAATATGTAATATAAATAAAACTATGGTAAATGTGACAAGCATTTAATAGGAAAATGCTAAGGA GGCCTCATAAATGACCCATAATTACCAACGTAGAATTTTTCAGTACATTTAGGGTTGCTGGATTTAGCA AATAAAAATAAAGATTGCCCAGTTAGATTTGAATTTCAGATAAACAATTAGTTTTTTAATATTTTACAT GGAATATTTGGAAAATACTTATACTAAAAAATTATTTGTTTGAAATTCAAATTTAACTGGGAGTCTTGT ATTTTATCTGGCAATCCTAAAATACATTGGTATGAAACAAATCACTTTTAGAAGTATATTGCTATTTTG ATTGGGTTGTTTTTGTGTGTAGAAACGTACAATAACAACTCAAAGGCACAGGAGATTTCTAAACATTGT GAAAAGTTGAATAGATTATATATTTATTCTCATAATACTTTCACTAATACTAAATAAAATTTGGGGAAC ACTTTTTATTTTTATATAATTTCCAATTTACAGAAAAGTTTCAAAAATAGTACAAAGAGCTCTCTTACC CAGATTCACTAATTGTTCATACGTGCTTTATCTTTCATGCTTTCTCTGTACACACACACACACACACAA ATTTTTCCTCAATCATTTGAAAGTCAGTTATAGGCATCATGCCCCTTAAACCCTAAATACTTCAGTGTG TAATACTGAATAATTACTAAAAATGATTTTCTCAGAAAAAAAAACTCCCACAATTCTGGAACTATAATA CTGTAAGCCTTAGAATAAATAATACTTTCAAGTTCCAATCTAAAGTTCTTTTTGAGTTTTGTTGCCCGT TTTATGCTTGATGTGTATAGTAATAGGGTAGGCTATTTATTTTATTAAAATTTTTTTTAGAGACAAGGT TTTGCTGTGTTGCCCAAGCTGGAACTTGAACGACTGGGCTGAAGTGATCTTCCCACCTCAGCCTCCCAA GTAGCTGGGAATACAGGTGTCTGCCACCATACCCAGTTTCATTTTTGTTTTTTATACCCGAAGTTCATT TCCTTTGTCTCCCTAAAACTGAACTGTAATTTTGGGAGGTTTTCATTAGTGGAAGCTCTTCATTTATAA AGCTATTTGAAGGGGTTTAGGAATTTATATCACATGGTAATTGTAGAGAAAAAGAAGCTATATACCTCA AAATCGTGCCCTCTTTACATATGTCTTATCAGGTATAACATGTTGAAATGTCACATTAGTAGTAAAGTG GGGTTTATTTATATAGTGGTTAAGAAATGTCAGTTTACACTGCTGTATACTTCTTCTTCTGTGTCCCTA AGGCCTGGTACAGTGCCAAGCACATACTTGGTATCCAATAAATATTTGTTGGATGAATGTATGCATATG TATTCAGTATATTTTAAATGAATAATCACAGAAGTAAGTTTAATAATTTGTCCTATTTTTCTCTGTCAC TTCCTTTTTCTCTAAGGCAGGAAAGGAAAGACATTAAACCATTAATTAAGTCAATCCTCTTGGAGACTC AAAAGACTATGAAGTGATCACTCTATATAAAATATAAATACAGTGTGGGTTCAAATGGCCATTTTTTGT GTGTCCCTCTCTCTCATCTTATGCTTCCCTTCCTTTTTTTATTTTTATTTTTTGGAGACGGAGTCTTG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_014584.3
Synonyms	ERO1-alpha; ERO1-L; ERO1-L-alpha; Ero1alpha; ERO1L; ERO1LA
Summary	Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1.[UniProtKB/Swiss-Prot Function]
Locus ID	30001
MW	78

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