TMEM108 (NM_001136469) Human 3' UTR Clone

Specifications

Product Data
Product Name	TMEM108 (NM_001136469) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CT124; RTLN
ACCN	NM_001136469
Insert Size	1819 bp
Sequence Data	Insert Sequence (showhide) >SC216534 3’UTR clone of NM_001136469 The sequence shown below is from the reference sequence of NM_001136469. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTGGGAAACGATCAAGTATCTGAGATCTAACTACAGCAGGCATCACTTTGCCATTCCGTATTTTTCGTC TCTAAATTATAAATATACAAATACATATATTATAAATATAACCTTTGTGTAACCCTGACTTAATGAGAA ACATTTTCAGCTTTTTTTCCTATGAATTGTCAACATCTTTTTTACAAGTGTGGTTTAAAAAAAAAAAAA ACTTTACAGAATGATCTGTGGCTTTATAAAATAAAGGTATTTCTAAGCAAAGCAGTTGCATTGATTGCT TCTCTTAATAACTATTCTTGAGCACCTGGGGATCCCAGGAACCCTGGTCAGGTGAGGTAAGAGACTGAC CTCCTGTAGAAGCTGAATGTTACAGTGCAAGCGCACGATTCTTTGAGTGATTCTTAAAGCTCTGGTTCC TCTTGATTTGGTGTGACCCCATTTCCTCCCTTCTCATACGCACACCTGTAAAGGGAACTGGACCGCCTC AGGGGAAGACGGCAGACTCATGCACAGAGAAGGAAAAGGGAACATCTCATCACCTCTGAGGATGAGTAC CCTGGAGCCTTATGACGGCACCATTGGATGTCATGTTTAATTCCATCCAAGTTGTGGATGGCAGGCAGG AGCATGGAGCCCTCAGGAATCCATGGAGGACATCAAGGCATCCCAAGGCCATATTCCCCTAACATTACT TCCACTGCTAACAACAGGACTGCCTTTCCCTGGTGGGAAAATGCTCCCTTTATGCCCATTCCTGTATCC CCTCCAACACCCACATCTGCATTAAACACCCGTGCCTTTCTCTTGGAGAGGGTTTAGATGCAGATCCCG GCCCTGGAGCTTTAAAATGCTTGCCCTTCCTTCTTCAAGGATCAAATGTTTATTGGGGTTCAGCTTTGT TTTCTCAAAAGGCCATGGTATCGTGCCCCTGAGGAACATGTTTATCTAAGAAGCTTTGAGGTAGTAGAG CGATAATTTTTGAAACCTTCCTCCTGCAATCTTTAAAAAAGAAAAAAAAGATTGCCCAAACAAATCATT TGGGAGAAGACATCATTATACTCCTACTTGGCACTGCAAACCTGCTCGCAGCACCAGCCGGTGGACTTG CCATCCAGCTCTCAGCTTCCACTGCTCCCCTTGTTCCCGGCCGGCTGGCTGCCTCCCCGTGCTGTGTCC AGCACGGCCAACAACGTCAGACCCTCAGAGACGCCCAAGGGGCTTCCAGAGGTGGCCGCTTCTCTATTT TTTCCTGATTGTGGCTGAGAGAGATGATTACTGCTTTGACACTTCCTTTCTCTAAAAGAAAAATAGTTT GATAGTATATTTTGAATATAGATGCTCTTATAGTCAGATTGGGAATTGAACTTGAATATTGGGTCATAT GTTTGTGTTGTTGCTGTAGTCTATCATGACTTTTTTCTTTCTGCATTTTCCTTAAAAAAAAAAAAAAGA TGGCCTTCAAAAGTGTGTTCTCAATGTTGTATGAACCTCCTTCACATGAGTTCGGTTGTTGTCTCTCTT CAAAGACTCTTCAACCCACAAAGAAGCAACTAAATGTTTCTCTAAGTTTAATTTTCTAGCGTGTTGTTG TCTTACCTTTTTAACCTTACCATAATATTTCTGTTAACTGTTACATTTAATATACCAATGTGTGTAAGT ATACAGAGAAAAATCTGTTTGTAAAGTAAAATTTATATATAATATATGTAATCAAAGATACATATGTTA TATATACATATGTGGATGTATGACTTATTTTTCCTTATCCACAGATTTCAGCTACCATGTATATATAAA TAAACTTATTTTATTAGCCAGAGGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001136469.3
Synonyms	CT124; RTLN
Summary	Transmembrane protein required for proper cognitive functions. Involved in the development of dentate gyrus (DG) neuron circuitry, is neccessary for AMPA receptors surface expression and proper excitatory postsynaptic currents of DG granule neurons. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. Through the interaction with DST, mediates the docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport. In hippocampal neurons, required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 and recruits the WAVE1 complex to facilitate actin-dependent BDNF:NTRK2 early endocytic trafficking and mediate signaling from early endosomes.[UniProtKB/Swiss-Prot Function]
Locus ID	66000
MW	70.1

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