YTHDC2 (NM_022828) Human 3' UTR Clone

Specifications

Product Data
Product Name	YTHDC2 (NM_022828) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CAHL; hYTHDC2
ACCN	NM_022828
Insert Size	1840 bp
Sequence Data	Insert Sequence (showhide) >SC216572 3’UTR clone of NM_022828 The sequence shown below is from the reference sequence of NM_022828. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCCTTGGGAGAAAAAAACACAACTGATTGACACTCAGAACTCTTAGCTGTGGAAGAACATCATGCCTAT TTATAACCACTGAATGCACTGACTTTCAAAAACTGAGGTGGGGTGTGTGTTACGAATGGGCTTTTTAAC ACTTTTAGAGTGTTGCTTTAGAACTACCATCTTCATATACAGGAGAAAGGAAGCATTTAAATTTTTATA GTGATTATAGAGAATGATTATATGATGTTTGTAATGAATAAAATAGTAGTTTCATTATTTGGCACAATA GCAGTTTATTTTAAACAAACAATTTGAAGTTAAACATTTCATTTTTAAAAACACTGAATTACAGTTCTT ATTGATGACTTTTTAATGCAGAGTAAGTTGTTTAAGAAAGGCCTGAATATATCAGAACATCTGAGCACC ATTTTAGAAGAGTCAACTCTTAAGATTATCATTAGAAAACAAATACGTCAACACCTATGAAAAGAAGCG GGGAAAACAACAACAAGGACAACAACAAAAAACCAGTGAAATTCTACAAGTGTCCCTTTTAAAAATAGT GTGTGCTAACTAAGGGCTATTCATTCTGCCATTTTTAACTTGAGACACATTTAAGAATAAAGTTGGATG TTCTTTTTCTGTGATTATGAAATGCAATAAAATCTGAATAAAGGGCAAAGTTTCTTCCTGATCAGATTA GATTAAGTGCTTAGTTTTATTCCTAATTCTGCCCCTTTTAACCTGATGTGTACCTTACTCTTTCCTCCC TCTCTTCCTCCCTTCCTCCTCTCCCCGCTCCTTTCCTGCATTTCTCCCTCCCTCCTTCCCTCGTCACAT CTCTTATATGAGCACAGTAATTATGACCTTTTTGTTTTGGCTACAACTTGATTGAAACAAGTTCAAAAT TTAAACAAGTTCATACAAGTTTTTAAAAATTCTCAACTGGTAGCTTGCTTGCTGTGCGTCTTCCAAACT AAAGCCTGCAAGCGCCACAATTCTAAGTGCCGCCTTCCATTTTTTTTCAGTATGTTTTCACTGGCTTAT GTTTTCAGATATGATTTTCCTTTTTCGCATATATGGTTTAATAAATGGGGGATAATTTTTTTTTTGTAA ATCCGTGCTTGTGCCAAGTCTCATATTTCTTTGCCATCTCAGAATTATCTTTTTACCACCACTGTTTAT AAAATTTCCTTAGAGACTTTTTGAAGGGAAAATAGAGCAACAGGGAAAAATGAAAGAAATGTCTTGGTT ACTGAGCTCTAAATAGACAGGTTTGATGGCACTTCTCATGATACATTTTAGTTATTCTTATAAAAGCAA ACAGGCAAACATGAGTGTAAATTAAAGACAAAAAGAAAACTCTGGTTTTATATTTGAGAACACGTGAAA AATCATGGGTCAACATAAAATCTTGAGAACCTTCTACTTTCTCTGGGAAAGCATTATATAGTGGTGCAT TAGTTTAGAAAGTCAGCTATGATTTTGCCTATAGTTCTAGTTATTAGCTTTGGGGTTTTCTTGTACTTT AAGACATACCTGTAAATTGAACCTATTTGAATTATATTCCACTGTATGTGTATTATGGCTCTTTTCCTA TTAGAGCAACTTGTGTTTCCCTGATAATGTGTACATTTTTTAGGCATGTACTTAATAGTTCACAATGTT CTAAATTTGGAAGGACTTAAAAAAAAAACTTGTTTAAATTTCCATCTGTTTTGTAATATCTAGCTCTAT ATGTAAATGATGGGTTTGTTGGTATTTAAAATGAATACAACTTGAATGTAATTAAAGTGCTGTTTTTTG GAAGCGATAAACTTTAAATATACTTATTAAAATGAAATTCTATTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_022828.5
Synonyms	CAHL; hYTHDC2
Summary	This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016]
Locus ID	64848
MW	71.5

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