UBE3B (NM_130466) Human 3' UTR Clone

Specifications

Product Data
Product Name	UBE3B (NM_130466) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BPIDS; KOS
ACCN	NM_130466
Insert Size	1950 bp
Sequence Data	Insert Sequence (showhide) >SC217138 3’UTR clone of NM_130466 The sequence shown below is from the reference sequence of NM_130466. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGCATGAACACGGGCTTTGAACTCTCCTAGCTCCTGTCCCAGCCCTGCCTCCAGGGCTCCTGGGCTGCC AGGGACCTTCAGCTCCCAGAGGCAGTGTGGTCCTGGGAATGTGACCAACATGCCAGGTGACATTGGCCC CTAGACCCTCTCTATAGCCATGAGACTCCTTGTGGCCTCAAGAAATTTAGACGCCCACGACAGCACTAC ACAGCATCTCCAGGTGATGCCCAAGGCACAGGGCTGCAGAAAATAAACCTCCAGATTCCACCAACACGG GTCCATTCTTCCTGGTGATGGCAGAGGGGCTTCTTTTAGCTAGTTTGATCTTTTGGGAGTCTGTCTTTC CTTAGCCGTCTGAGTGAGCTGTGTATGAACAAGTCCCAGGAGTTCCAAGAGTCTAGAGTGGTTTTTGCA GCATGGGTTGAGTGTACAAAGCCTACTGTGCGTGAGATCCTCTCCTTCCGTTTCTGAAATCTCTTACTC AGGTAAGGCCTCGCCAAGCCTCTATGCACCCCACAAAGTTTCTGCCTCCATGCCGTCCACAGCGCCTCT TCCCAGACAGCCAGGCCCATCTGCTGCCCAGGGAAGCGCAGGCGCCTGCTAGGGACGCTATGGACACCG TGAGTCCAAGGCGCTGCTCCTGCCTTGAAGCCACGCGCTCCACGCCGCGGCCCTCCCATTTTCTGCGTC CTCAGCGGGCTGAGCTGCCAGAGAGTCTTCCCGGACCTATTCCCGTCCTATGCATTCACATTGGCATCC TGGTTTGGGGGAAGAAAAACAACGGCCCTTAGCAGCAGCCCCGTTTCCAGAATGTGCTGCCTGTTCCCC AAAGCCTGCTTGTCCCGCGGAGGACGGCTGCCTTTGACCCTGCTTATTTGTCTCACTGGTTATCTAATG AGGAACAAACACTAACCTAAGGTACACATCCCATCTGGGCGGTGGCTTCACTCCTGAGTCTGCAAAATC CCAGGAAACTTGGGTCTTGCTGCCCATCCTTCCTCAGCACAGGGAACCCGGAAGCCCGTTGCACTGACA GAGGCTCACACCCTCTGGGTTTTTTGTTTTTTTTTTAAACTTCATTTCTCTTCCAACCCATTGTGTTCC TCTGCCCTCATTCTTTACCTTTGTTGTAAGAACTTTAGCTCCAGGGAACTGAGGCAGAGGCCCTGTTTG TGGTCTGTGTTGACAGCCACCCACCCTCTCCCACCTCATGCTCCTGCACCTGCACCACCAAGGTTGATG CCGGATTCGAAGCCAGGAAGGCCCAGTCCCTCCTCTGCTCTCCTCAAAGACGCAAAACATTTTCCAACA AGAGCTGTCACAGTGGCAGCAAAGCAGGGGCCACCCGTCTCCACAGTCCTTCAGAGTTTCAGCTGCATC CTGGTGTCCCACCCAGGTCGAGCCCCCAGGCTTCTGGAAAAGAGTGTGTGCTCTACTTTGATGGAAACA TGGCAAGGAATTTAAAGACAGGAATGTATTAATATTATTGAAGGTGTGTTCGTAACCTCTGATTCTGTG GACTTGCCACTTTCTCCAAACGCTCGGTTCCTTTGAAGATTTCTTCTGAACGTGTGTGCGCACGCTGGG CGGGTTCGTGCATACATGCGGGGACCCCAGACTGTCAGCACAGGGAAGATGGATCCCATCCTAATTTTT ATCACCTGAAGGTTGGAACCAGTGAGGGACTGGGAGAGAGTGATTTATAAGCACCAATATCAACTTCAT GTGGATTTTTGACAAGGAGGGGTAGTTTGTAATTTCATTTAAATTCTTTTCAGCAGCTGGAAATATTGC ACTATCTGAAACACTGAATCTCCTTTTGTAACTGGTGTTCACTGACACCTTGATGGCTCTTGATGGCTC TAAAAAGTTGTAGGATTTTTTGTTTTTGTAGCTAACTTATGGATTGAGATGTGATCAAAGGCTTTATTA AATTTGTACTTCAGCATA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_130466.4
Synonyms	BPIDS; KOS
Summary	The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin-protein ligases. This gene encodes a member of the E3 ubiquitin-conjugating enzyme family which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and transfers the ubiquitin to the targeted substrates. A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases. Shorter isoforms of this protein which lack the C-terminal HECT domain are therefore unlikely to bind E2 enzymes. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2012]
Locus ID	89910
MW	72.9

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