Ipo5 (NM_023579) Mouse Untagged Clone
CAT＃: MC223537
Ipo5 (untagged) - Mouse importin 5 (Ipo5), (10ug)
CNY 14060.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1110011C18Rik; 5730478E03Rik; AA409333; C76941; IMB3; Kpnb3; Ranbp5 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223537 representing NM_023579
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGCGGCCGCGGCGGAGCAGCAACAGTTCTACCTGCTCCTGGGAAACCTGCTCAGCCCCGACAATG TGGTCCGGAAACAGGCGGAGGAAACCTATGAGAATATCCCAGGCCGGTCCAAGATCACATTCCTCTTACA AGCCATCAGAAACACAACCGCTGCCGAGGAGGCTAGACAAATGGCTGCTGTTCTCCTAAGACGTCTTTTG TCCTCTGCATTTGATGAAGTCTACCCAGCTCTTCCATCAGATGTCCAGACTGCCATCAAGAGTGAATTGC TAATGATCATTCAGATGGAAACACAATCCAGCATGAGGAAGAAAATCTGTGATATTGCTGCAGAATTGGC CAGGAATTTAATAGATGAGGACGGCAACAACCAGTGGCCTGAAGGTTTGAAGTTCCTCTTTGATTCAGTC AGCTCACAAAACATGGGACTCCGGGAAGCTGCCCTTCACATATTTTGGAACTTTCCTGGAATTTTTGGGA ACCAACAACAGCACTATTTGGACGTCATCAAACGGATGTTAGTTCAGTGTATGCAAGATCAGGAGCATCC TTCGATCAGGACACTGTCTGCCAGAGCTACTGCTGCCTTCATACTTGCCAATGAGCATAATGTCGCTCTG TTCAAACACTTTGCAGACTTGCTGCCTGGATTCTTACAGGCTGTCAATGACTCATGCTACCAGAATGATG ACTCGGTCCTAAAATCCCTTGTTGAGATTGCAGACACCGTACCAAAGTACTTGCGCCCTCACTTAGAAGC AACTCTGCAGTTGAGTCTGAAGTTGTGTGGAGACACTAACCTCAATAATATGCAGCGCCAGCTTGCCCTT GAAGTGATTGTGACACTGTCAGAGACTGCAGCTGCTATGTTAAGAAAGCATACCAGTCTCATCGCACAGA CGATTCCTCAGATGTTGGCAATGATGGTTGACCTAGAAGAAGATGAGGACTGGGCAAATGCTGATGAGCT AGAAGATGATGATTTCGATAGCAATGCAGTTGCTGGTGAGAGTGCATTAGACCGAATGGCCTGTGGACTT GGTGGAAAGCTCGTTCTGCCCATGATTAAGGAACACATTATGCAAATGCTTCAAAACCCTGATTGGAAAT ACAGGCATGCAGGACTGATGGCCCTATCCGCCATTGGCGAAGGATGCCACCAGCAGATGGAAGGAATTCT AAATGAGATTGTAAATTTTGTCTTGCTTTTCCTCCAGGATCCTCATCCGAGAGTCCGGTATGCAGCCTGC AATGCTGTGGGTCAAATGGCTACAGATTTTGCACCTGGTTTTCAAAAGAAATTTCATGAGAAGGTGATTG CAGCTTTGCTTCAGACCATGGAAGACCAAGGCAACCAGCGGGTGCAGGCCCATGCAGCGGCTGCCCTCAT TAACTTCACTGAAGATTGTCCCAAGTCGCTGCTTATTCCCTACTTGGATAACTTGGTGAAGCACCTGCAC TCCATTATGGTGCTCAAGCTCCAGGAGCTGATTCAGAAAGGCACCAAGTTAGTTTTGGAACAAGTTGTGA CATCCATTGCATCAGTTGCAGATACTGCAGAAGAAAAGTTTGTCCCCTACTATGACTTGTTTATGCCATC ACTGAAGCACATTGTCGAGAACGCAGTCCAGAAGGAGCTGAGACTGCTGCGAGGGAAGACCATCGAGTGC ATCAGCCTCATCGGGCTGGCCGTCGGGAAGGAGAAATTCATGCAGGATGCTTCAGATGTGATGCAGCTAT TGTTGAAGACACAGACAGACTTCAATGATATGGAAGATGACGACCCCCAGATTTCTTACATGATCTCAGC ATGGGCCAGGATGTGCAAAATCCTTGGGAAAGAATTCCAGCAGTACCTTCCCGTGGTTATGGGGCCGCTG ATGAAGACTGCTTCAATTAAGCCTGAAGTGGCCCTTCTAGACACCCAGGACATGGAGAATATGAGTGATG ATGACGGTTGGGAATTTGTGAACCTCGGAGATCAGCAAAGTTTTGGTATTAAAACTGCAGGACTGGAAGA AAAGTCAACGGCTTGTCAGATGTTGGTTTGCTATGCTAAGGAATTAAAGGAAGGTTTTGTGGAATACACT GAACAGGTTGTCAAACTGATGGTCCCGCTGCTGAAATTTTATTTCCACGATGGGGTCCGAGTGGCAGCAG CAGAGTCCATGCCTCTTCTGCTTGAGTGTGCGAGAGTCCGGGGTCCCGAGTACCTTACACAGATGTGGCA CTTCATGTGCGACGCTCTCATCAAGGCCATCGGCACAGAGCCCGACTCAGATGTCCTCTCGGAGATCATG CATTCCTTTGCAAAGTGCATTGAGGTCATGGGAGACGGGTGCCTCAACAATGAGCACTTTGAGGAGCTGG GAGGCATCCTGAAGGCGAAGCTTGAAGAACATTTCAAAAATCAGGAGTTGCGGCAAGTTAAAAGACAAGA TGAAGACTATGACGAGCAGGTTGAAGAGTCACTACAAGATGAGGATGATAATGATGTTTATATACTGACT AAAGTGTCGGATATTTTACACTCAATATTCAGTAGCTACAAAGAAAAGGTGTTGCCGTGGTTTGAACAGC TGCTCCCATTAATTGTCAACCTGATTTGTCCGCAAAGACCATGGCCAGACAGACAATGGGGATTGTGCAT CTTCGATGATATCGTAGAACACTGTAGTCCAGCTTCATTTAAGTATGCAGAATATTTCATAAGTCCAATG CTCCAGTATGTGTGTGACAACAGCCCAGAAGTCAGGCAAGCTGCGGCATATGGCCTCGGCGTCATGGCGC AGTTTGGTGGAGATAACTACCGCCCTTTCTGTACCGATGCACTCCCGCTGCTTGTAAGAGTCATTCAGGC TCCAGAGGCTAAGACCAAAGAAAATGTCAACGCCACGGAGAACTGCATCTCAGCAGTGGGAAAGATCATG AAGTTCAAGCCCGACTGTGTGAATGTGGAGGAGGTCTTACCACACTGGCTGTCATGGCTGCCCCTACACG AAGATAAAGAAGAAGCTGTCCAGACCTTCAGTTACCTGTGCGACCTGATTGAAAGTAATCACCCAATTGT TCTTGGCCCAAACAATACCAATCTACCGAAAATATTCAGTATAATTGCAGAAGGAGAAATGCATGAGGCC ATTAAACATGAAGACCCCTGTGCCAAACGCCTGGCCAATGTAGTTCGCCAAGTACAGACTTCTGGAGGAT TGTGGACTGAATGCATAGCTCAACTCAGTCCGGAGCAGCAGGCAGCCATCCAGGAGCTCCTGAACTCTGC CTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_023579 |
| Insert Size | 3294 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_023579.4, NP_076068.1 |
| RefSeq Size | 4598 bp |
| RefSeq ORF | 3294 bp |
| Locus ID | 70572 |
| UniProt ID | Q8BKC5 |
| Gene Summary | Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. Binds to a beta-like import receptor binding (BIB) domain of RPL23A. In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones. Binds to CPEB3 and mediates its nuclear import following neuronal stimulation (PubMed:22730302).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG211627 | Ipo5 (tGFP-tagged) - Mouse RAN binding protein 5 (Ranbp5) |
CNY 10550.00 |
|
| MR211627 | Ipo5 (Myc-DDK-tagged) - Mouse importin 5 (Ipo5) |
CNY 7640.00 |
|
| MR211627L3 | Lenti ORF clone of Ipo5 (Myc-DDK-tagged) - Mouse importin 5 (Ipo5) |
CNY 11500.00 |
|
| MR211627L4 | Lenti ORF clone of Ipo5 (mGFP-tagged) - Mouse importin 5 (Ipo5) |
CNY 11500.00 |
