Trp53bp2 (NM_173378) Mouse Untagged Clone
CAT＃: MC223694
Trp53bp2 (untagged) - Mouse transformation related protein 53 binding protein 2 (Trp53bp2), (10ug)
CNY 14540.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 53BP2; AI746547; ASPP2; PPP1R13A; Tp53bp2; X98550 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223694 representing NM_173378
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCGGTTCGGGTCCAAAATGATGCCGATGTTCCTGACAGTTTACCTCAGTAACAGTGAGCAGCACTTCA CAGAAGTTCCTGTTACCCCAGAGACAATATGCAGAGATGTGGTGGATCTGTGCAAGGAGCCTGGAGAGAA CGACTGCCATTTAGCCGAAGTGTGGTGTGGCTCTGAACGCCCAGTTGCTGATAACGAACGGATGTTTGAT GTTCTTCAGCGGTTTGGAAGTCAAAGGAATGAAGTTCGCTTCTTTCTTCGTCATGAACGCCCCCCTAACA GGGACATTGTGAGTGGACCGAGATCCCAAGATCCAAGTGTAAAAAGAAATGGTGTCAAAGTTCCCGGCGA GCATCGGAGGAAGGAGAATGGGGTTAACAGTCCTAGGCTGGACCTGACGCTTGCTGAGCTCCAGGAGATG GCATCTCGCCAGCAGCAGCAGATCGAGGCCCAGCAACAAATGCTGGCTACTAAGGAGCAACGCTTAAAGT TTTTAAAACAGCAAGATCAACGTCAACAGCAACAAGCTGCTGAACAGGAGAAACTTAAGAGGCTTAGAGA AATAGCTGAAAGTCAGGAAGCTAAGCTTAAGAAAGTGAGAGCGCTAAAGGGCCATGTGGAGCAAAAGAGG CTGAGCAACGGAAAACTCGTGGAGGAGATCGAGCAGATGAATAGCTTGTTCCAGCAGAAGCAGAGGGAGC TGGTGCTGGCTGTGTCGAAAGTGGAGGAGCTGACGAGGCAGCTGGAGATGCTGAAGAACGGCAGGATCGA TGGCCACCACGACAACCAGTCGGCCGTGGCTGAGCTGGACCGCCTTTACAAGGAGCTGCAGTTAAGAAAC AAACTGAACCAAGAGCAGAATGCCAAGCTGCAACAACAGAGGGAGTGTTTGAATAAGCGCAATTCAGAGG TGGCCGTCATGGATAAACGCGTCAGTGAGCTGAGGGACCGGCTGTGGAAGAAGAAGGCAGCACTGCAGCA GAAAGAGAATCTCCCGGTTTCACCTGATGGAAATCTTCCCCAACAAGCAGTGTCAGCCCCAAGTCGTGTG GCTGCTGTAGGCCCTTACATCCAGTCATCCACTATGCCACGGATGCCCTCCAGACCTGAGCTGCTCGTGA AGCCAGCCCTGCCTGATGGTTCCTTGCTCATGCAGTCAGCAGAGGGGCCAATGAAGATACAGACACTGCC CAATATGAGGTCTGGGGCTGCTTCACAAAGTAAAGGCTCTAAAGCTCACCCAGCTAGCCCCGATTGGAAC CCTTCCAATGCCGACCTCTTACCCAGCCAAGGCTCTTCTGTACCCCAGAGTGCTGGAACTGCTCTGGACC AAGTTGACGATGGGGAGATTGCTGTGAGGGAGAAAGAGAAGAAAGTGCGTCCCTTTTCCATGTTTGACAC AGTGGACCAGTGTGCTGCCCCACCCTCCTTTGGTACCCTGAGGAAAAACCAGAGCAGCGAGGACATCTTG CGGGATGCTCAGGCTGTAAATAAAAATGTAGCTAAAGTACCACCTCCCGTTCCTACAAAGCCAAAACAGA TTCATTTGCCTTACTTTGGACAAACGGCTCAGTCGCCTTCTGACATGAAGCCAGATGGAAATGCTCAGCA ATTGCCAATAGCTGCTACATCCGTGGGGGCTAAGCTCAAGCCAGCAGGGCCACAGGCAAGGATGCTGCTG TCTCCTGGTGCCCCTTCAGGTGGTCAGGACCAAGTCCTGTCTCCAGCATCTAAGCAAGAAAGTCCTCCTG CTGCTGCAGTCCGGCCCTTCACGCCCCAGCCGTCCAAGGACACCTTCCCTCCAGCCTTTCGAAAACCCCA GACTGTGGCAGCAAGCTCCATCTATTCCATGTACACCCAGCAACAGGCACCAGGAAAAAACTTCCAGCAG GCTGTGCAGAGTGCCTTGACCAAGACGCAACCCAGAGGCCCCCACTTTTCAAGTGTGTATGGCAAGCCTG TGATAGCTGCTGCCCAGAATCCACAACAGCACCCAGAGAACATTTACTCCTGTAGCCAGGGGAAGCCTGG CAGTCCGGAGCCCGAGACAGAGACCGTTTCTTCAGTTCATGAGAGCCATGAAAACGAAAGGATTCCTCGA CCACTCAGCCCAACAAAATTACTGCCTTTCTTGTCTAACCCTTATCGAAACCAGAGCGATGCTGACTTAG AAGCCCTGAGGAAAAAATTGTCGAATGCACCACGGCCACTAAAGAAACGTAGCTCCATTACAGAACCAGA AGGCCCTAATGGGCCAAATATTCAGAAACTTTTGTATCAGAGGACCACCATAGCTGCCATGGAGACCATC TCAGTCCCCTCACACCCATCTAAGTCACCAGGCTCAGTGACTGTCAATCCAGAGAGCTCCGTTGAAATCC CAAATCCATATTTACATGTGGAGCCAGAGAAGGAGGTGGGCTCTTTAGTCCCTGAACCACTGTCCCCAGA GGATATGGGGAGTGCCAGTACGGAGAACAGTGACGTGCCAGCTCCTTCTGCAGGCCTTGAGTATGTGTCT GAGGGAGTCACAGACAGCAGTACCAATCTGCAGAATAACGTAGAAGAAACAAACCCAGAGGCTCCCCACT TACTTGAAGTGTACCTAGAAGAATACCCCCCATACCCACCCCCTCCATACCCATCTGGGGAGCCAGAGGT GTCCGAAGAAGACTCCGCACGTATGCGCCCACCTGAAATCACCGGGCAGGTGTCTCTGCCTCCTGGCAAA AGGACAAACTTGCGGAAAACTGGCTCCGAGCGGATTGCTCACGGGATGAGGGTGAAATTCAACCCCCTTG CTTTGCTGCTAGATTCATCTCTGGAGGGAGAGTTTGATCTTGTACAGAGAATTATCTATGAGGTTGATGA CCCAAGCCTACCAAATGATGAGGGCATCACAGCTCTTCATAATGCTGTGTGTGCAGGCCACACAGAAATT GTGAAGTTCCTGGTACAGTTCGGTGTGAATGTAAATGCAGCAGATAGTGATGGATGGACGCCATTGCATT GTGCTGCCTCCTGCAACAATGTCCAAGTGTGTAAGTTCCTGGTGGAGTCTGGAGCAGCTGTGTTTGCTAT GACCTACAGTGACATGCAGACTGCTGCAGACAAGTGCGAGGAAATGGAGGAAGGCTACACGCAGTGCTCC CAGTTTCTCTATGGCGTTCAGGAGAAGATGGGCATAATGAACAAAGGCGTCATTTATGCACTGTGGGATT ACGAGCCGCAGCATGACGATGAGCTGCTCATGAAAGAAGGAGATTGCATGACCGTCATCCGCAGAGAAGA TGAAGAGGAGATCGAGTGGTGGTGGGCGCGCCTTAACGATAAGGAAGGATATGTTCCACGCAACTTGCTA GGACTATACCCAAGAATTAAACCAAGACAAAGGAGCTTGGCCTGA AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-RsrII |
| ACCN | NM_173378 |
| Insert Size | 3405 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_173378.2, NP_775554.2 |
| RefSeq Size | 4377 bp |
| RefSeq ORF | 3405 bp |
| Locus ID | 209456 |
| UniProt ID | Q8CG79 |
| Gene Summary | Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates p53/TP53 by enhancing the DNA binding and transactivation function of p53/TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42 (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG227675 | Trp53bp2 (tGFP-tagged) - Mouse transformation related protein 53 binding protein 2 (Trp53bp2), (10ug) |
CNY 10830.00 |
|
| MR227675 | Trp53bp2 (Myc-DDK-tagged) - Mouse transformation related protein 53 binding protein 2 (Trp53bp2) |
CNY 7896.00 |
|
| MR227675L3 | Lenti ORF clone of Trp53bp2 (Myc-DDK-tagged) - Mouse transformation related protein 53 binding protein 2 (Trp53bp2) |
CNY 11780.00 |
|
| MR227675L4 | Lenti ORF clone of Trp53bp2 (mGFP-tagged) - Mouse transformation related protein 53 binding protein 2 (Trp53bp2) |
CNY 11780.00 |
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