Myo18a (NM_001291213) Mouse Untagged Clone

Specifications

Product Data
Type	Mouse Untagged Clone
Tag	Tag Free
Synonyms	MAJN; MyoPDZ; MysPDZ; SP-R210
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >MC229702 representing NM_001291213 Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTTTAACCTCATGAAGAAAGATAAGGACAAAGATGGCGGGCGGAAGGAGAAGAAGGAAAAAAAGGAGA AGAAGGAGAGGATGTCTGCGGCAGAACTGCGGAGCCTGGAAGAGATGAGCATGCGCCGTGGCTTTTTCAA CTTGAACCGGTCCTCCAAGCGGGAATCTAAGACGCGCCTGGAAATCTCCAACCCCATCCCTATCAAGGTG GCCAGTGGCTCTGACCTGCACCTGACGGACATTGACTCTGACAGCAATCGGGGTAGCATCATCCTGGACT CAGGACACCTAAGCACAGCCAGCTCCAGTGATGACCTCAAGGGTGAAGAAGGCAGCTTCCGGGGCTCTGT GCTGCAGCGGGCAGCCAAGTTCGGTTCACTGGCCAAGCAGAACTCTCAGATGATTGTCAAACGTTTTTCC TTCTCTCAACGGAGCCGGGATGAGAGTGCCTCGGAGACCTCAACCCCCTCAGAGCACTCTGCAGCCCCAT CACCTCAGGTAGAGGTGCGGACGCTTGAGGGACAGCTAATGCAGCATCCTGGGCTAGGCATTCCTCGACC AGGACCACGGTCTCGAGTCCCTGAGCTGGTGACTAAAAGATTCCCAGCTGATCTACGTCTTCCCGCTCTG GTGCCACCACCACCTCCTGCTCTCCGGGAGCTGGAGTTACAACGAAGACCCACAGGAGACTTTGGCTTCT CACTGCGGCGCACAACCATGCTGGATCGGGCCCCTGAGGGTCAGGCTTATCGACGGGTGGTTCACTTTGC TGAGCCAGGGGCAGGCACCAAGGACCTGGCCTTGGGGCTGGTACCAGGAGATCGACTGGTGGAGATTAAT GGACAGAATGTGGAGAATAAATCCAGGGATGAAATTGTGGAGATGATCCGGCAGTCTGGGGACAGTGTGC GGCTCAAGGTACAGCCCATCCCAGAGCTTAGCGAGCTGAGCCGGAGCTGGCTTCGGACTGGCGAGGGACA CCGCAGGGAGCCGGCTGATCTGGACCCCGAGGCCGCCTCTCCTGCCTACAGCCAGGTAGGGTGCTCCTGC CCCACCCAGGAGCCCTCTGCTTTCTCCAGTGACAACCCACCACCCCCACCCTGTACCTGGGCTGGCGTCT GTGCTCGGGCCTCCTGCTGGAGTGCCAAGACGGAAGAGCAGATTGCCGCTGAAGAGGCCTGGTATGAGAC GGAGAAGGTGTGGCTGGTCCATAGAGATGGATTCTCCTTAGCCAGCCAGCTCAAGTCTGAGGAGCTCAGC CTACCCGAGGGGAAGGCGCGTGTGAAGCTGGACCATGACGGAGCCATCCTGGATGTGGATGAAGATGATA TAGAGAAGGCTAATGCTCCTTCATGTGACCGTCTAGAAGATCTGGCCTCACTGGTATACCTCAACGAGTC TAGCGTCCTGCATACACTGCGCCAGCGCTATGGGGCTAGCCTGCTACACACCTATGCTGGCCCCAGCCTG CTTGTCCTTAGCACCCGAGGGGCTCCTGCTGTGTATTCAGAGAAGGTGATGCACATGTTCAAGGGGTGTC GGCGGGAGGACATGGCACCCCACATCTACGCTGTAGCCCAGACTGCATATAGGGCGATGTTGATGAGTCG TCAGGACCAGTCCATTGTCCTTCTGGGTAGTAGTGGCAGTGGCAAGACTACCAGCTTTCAGCATCTGGTG CAGTATCTGGCTACCATCGCGGGTACCAGTGGGACCAAGGTGTTCTCAGTGGAGAAGTGGCAGGCTCTGT CCACCCTCCTGGAAGCCTTTGGGAACAGCCCCACCATCATGAATGGCAGTGCCACCCGCTTCTCCCAGAT CCTCTCCCTGGACTTTGACCAAGCTGGCCAGGTGGCTTCGGCCTCCATCCAGACAATGCTCCTGGAGAAG CTGCGTGTGGCCCGGCGCCCAGCCAGTGAGGCTACTTTCAATGTCTTCTACTACTTGCTGGCCTGTGGGG ATGCCACCCTCAGGACAGAGCTCCACCTGAACCACTTGGCAGAGAACAATGTGTTTGGAATTGTGCCACT GTCCAAGCCTGAGGAGAAGCAGAAGGCTGCACAGCAGTTCAGTAAGCTCCAGGCTGCCATGAAGGTGCTG GCCATCTCCCCCGAGGAACAGAAGACCTGCTGGCTCATCCTGGCTTCCATCTACCACCTGGGGGCTGCTG GAGCTACCAAAGAAGCTGCTGAAGCTGGACGAAAGCAGTTTGCCCGCCACGAATGGGCCCAGAAGGCAGC ATACCTGCTGGGCTGCAGCTTGGAAGAGCTGTCCTCGGCTATCTTCAAACACCAGCTAAAAGGAGGCACC CTGCAACGGTCCACCTCCTTCCGTCAGGGCCCTGAGGAGAGCGGCCTGGGAGAGGGCACCAAACTGAGTG CTCTGGAGTGCTTAGAGGGTATGGCGTCTGGCCTCTACAGTGAGCTCTTTACTCTCCTCATCTCCCTGGT AAACAGGGCTCTCAAGTCCAGCCAGCACTCACTCTGTTCCATGATGATCGTGGACACACCAGGCTTCCAG AACCCTGAATGGGGCGGCTCGGCCCGTGGAGCCTCCTTCGAGGAGCTGTGCCACAACTATGCCCAGGACA GGCTGCAGAGGCTGTTCCACGAGCGCACCTTCCTCCAGGAGTTGGAGAGATACAAGGAGGATAACATAGA ACTGGCGTTTGATGACTTGGAGCCAGTTGCAGATGACTCCGTGGCTGCTGTGGACCAGGCTTCCCACCTG GTTCGCTCACTGGCCCATGCCGATGAGGCAAGAGGGCTACTGTGGCTCCTGGAAGAGGAGGCACTGGTGC CTGGTGCGACAGAGGATGCCCTCCTTGATCGTCTTTTCTCCTATTATGGCCCCCAGGAGGGTGACAAAAA AGGCCAGAGTCCTCTTCTGCGAAGTAGCAAACCTCGGCACTTTCTCCTGGGCCACAGCCACGGTACCAAC TGGGTGGAGTACAACGTGGCTGGCTGGCTGAATTACACCAAGCAGAACCCAGCCACCCAGAATGCACCCC GGCTTCTGCAGGACTCCCAGAAAAAGATCATCAGTAACCTGTTTCTGGGCCGGGCGGGCAGTGCCACGGT GCTCTCAGGCTCGATTGCAGGCCTGGAAGGTGGCTCCCAGCTGGCCTTGCGCCGGGCAACCAGCATGAGG AAAACCTTCACCACCGGCATGGCCGCTGTCAAGAAGAAGTCGCTGTGCATACAGATTAAGCTGCAAGTAG ATGCCCTCATTGATACCATCAAGAGGTCCAAGATGCATTTCGTGCACTGCTTCCTTCCTGTGGCCGAGGG CTGGCCTGGGGAGCCCCGGTCTGCCTCTTCCCGCAGAGTCAGCAGCAGCAGTGAGCTGGACCTGCCCCCG GGAGACCCCTGTGAGGCTGGGCTGCTACAACTGGATGTGTCCCTGCTCCGAGCCCAGCTCCGGGGATCCC GCCTGCTTGATGCGATGCGCATGTACCGCCAAGGTTACCCAGACCACATGGTGTTTTCTGAGTTCCGCCG GCGCTTTGATGTCCTGGCTCCACACCTGACCAAGAAACATGGTCGTAACTACATCGTGGTGGATGAGAAG CGGGCTGTGGAAGAGCTGCTGGAGTCCCTGGACCTGGAAAAGAGCAGCTGCTGTCTGGGCCTAAGCCGGG TGTTCTTCCGGGCAGGCACGTTGGCACGGTTGGAAGAACAACGAGACGAGCAAACCAGCAGGCACCTGAC CCTGTTCCAGGCAGCCTGCCGGGGCTACCTTGCCCGCCAGCACTTCAAGAAGAGAAAGATCCAGGACCTG GCCATTCGCTGTGTGCAGAAGAACATCAAGAAGAACAAGGGGGTGAAGGACTGGCCCTGGTGGAAGCTCT TCACCACCGTGCGGCCCCTCATCCAAGTTCAGCTGTCAGAGGAGCAGATCCGAAACAAAGACGAGGAGAT CCAGCAGCTGCGCAGCAAGCTTGAGAAGGTGGAGAAGGAGAGGAACGAGCTCCGACTCAGCAGTGACCGG CTAGAGACCCGGATCTCAGAACTGACATCGGAGCTGACTGATGAACGCAACACGGGAGAGTCCGCCTCCC AGCTGCTGGACGCGGAGACAGCCGAGAGGCTCCGGACCGAGAAGGAGATGAAAGAGCTACAGACCCAGTA TGACGCACTGAAGAAGCAGATGGAGGTGATGGAGATGGAAGTGATGGAAGCCCGGCTCATTCGGGCAGCC GAGATCAACGGGGAGGTGGATGATGATGATGCAGGGGGAGAGTGGAGGCTGAAGTACGAGCGAGCTGTTC GGGAGGTGGACTTCACCAAGAAGCGGCTCCAGCAGGAGCTGGAAGACAAGATGGAGGTGGAACAGCAGAG CAGGAGGCAGCTGGAGAGGCGGCTTGGGGACCTGCAAGCAGATAGTGATGAGAGTCAACGGGCACTGCAG CAGCTCAAGAAGAAGTGCCAAAGGCTCACAGCTGAGCTGCAGGACACCAAGCTGCACCTGGAGGGCCAGC AGGTCCGAAACCACGAGCTGGAGAAGAAGCAGAGGAGGTTCGACAGTGAGCTTTCCCAGGCCCACGAGGA GACGCAGCGGGAGAAGCTGCAGAGGGAGAAACTCCAGCGGGAGAAGGACATGCTCCTGGCTGAGGCTTTC AGCTTGAAGCAGCAAATGGAGGAAAAAGACTTGGACATTGCGGGGTTTACCCAGAAGGTGGTTTCCTTGG AGGCTGAGCTTCAGGACATTTCTTCTCAAGAGTCTAAGGATGAGGCTTCTCTGGCCAAGGTCAAGAAGCA GCTCCGGGACTTGGAGGCCAAGGTCAAGGACCAGGAAGAGGAGCTGGATGAGCAGGCTGGGAGTATACAG ATGCTGGAGCAGGCCAAGCTGCGTCTGGAGATGGAGATGGAGAGAATGAGACAGACCCATTCCAAGGAGA TGGAGAGTCGGGATGAGGAGGTGGAAGAGGCCCGGCAGTCATGTCAGAAGAAGTTAAAACAGATGGAAGT GCAGCTCGAGGAGGAGTATGAAGACAAGCAGAAGGCGCTGCGGGAGAAACGGGAGCTGGAGAGCAAGCTC TCCACGCTCAGTGACCAGGTGAACCAGCGGGACTTTGAATCAGAGAAGCGGCTACGGAAAGACCTGAAGC GCACCAAAGCGCTGCTGGCAGATGCCCAGATCATGCTGGACCACTTAAAGAACAATGCCCCGAGCAAGAG GGAGATTGCCCAGCTGAAGAACCAGCTGGAAGAGTCGGAATTCACCTGTGCAGCAGCTGTAAAGGCACGG AAAGCGATGGAGGTGGAGATGGAAGACCTGCACCTGCAGATTGATGACATCGCCAAAGCCAAGACAGCGC TGGAGGAGCAACTGAGTCGACTTCAGCGTGAGAAAAACGAGATTCAAAACCGGCTGGAAGAGGATCAGGA GGACATGAATGAGCTGATGAAGAAGCACAAGGCAGCTGTGGCCCAGGCCTCCCGGGACATGGCACAGATG AACGATCTCCAGGCTCAGATTGAAGAGTCCAACAAGGAGAAGCAAGAGCTACAGGAGAAGCTACAAGCTC TGCAGAGCCAGGTGGAGTTCCTGGAGCAGTCCATGGTGGACAAGTCCCTCGTCAGCAGGCAGGAAGCGAA GATCAGGGAGCTGGAGACACGCCTGGAGTTCGAAAAGACCCAAGTGAAGCGCCTGGAGAACCTGGCCAGT CGGCTCAAAGAAACCATGGAGAAGCTGACTGAGGAACGGGACCAGCGCGCCGCAGCTGAGAACCGTGAGA AGGAGCAGAACAAGAGGCTCCAGCGACAGCTTCGTGACACCAAGGAGGAGATGAGCGAGCTTGCCAGGAA GGAAGCCGAGGCTAGCCGCAAGAAGCATGAACTGGAGATGGACCTGGAGAGCCTGGAAGCTGCTAACCAA AGCCTGCAAGCCGACCTAAAGCTGGCGTTCAAACGCATTGGGGACTTGCAAGCTGCCATTGAGGATGAGA TGGAAAGTGACGAGAACGAGGACCTCATCAACAGTGAGGGGGACTCAGATGTGGACTCAGAGCTGGAGGA CCGGGTCGACGGGGTCAAGTCCTGGTTGTCAAAGAACAAGGGACCTTCTAAGGCACCTTCTGACGATGGC AGCTTGAAGAGTTCCAGCCCAACCAGCCACTGGAAGCCACTCGCCCCTGACCCATCGGATGATGAGCATG ATCCTGTGGACAGCATCTCCAGACCCCGGTTCTCCCACAGCTATCTGAGTGACAGCGACACAGAGGCCAA GCTGACAGAGACCAGTGCATAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001291213
Insert Size	6252 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001291213.1, NP_001278142.1
RefSeq Size	7504 bp
RefSeq ORF	6252 bp
Locus ID	360013
UniProt ID	Q9JMH9
Gene Summary	May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035). Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (By similarity). May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (PubMed:10733906). Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking (PubMed:25965346). Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages (PubMed:21123169). Strongly enhances natural killer cell cytotoxicity (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

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