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Cgas (NM_173386) Mouse Tagged ORF Clone
CAT＃: MR213022
- TrueORF®
MB21D1 (Myc-DDK-tagged) - Mouse Mab-21 domain containing 1 (Mb21d1)
ORF Plasmid: tGFP
"NM_173386" in other vectors (4)
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CNY 5,672.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | E330016A19Rik; Mb21d1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR213022 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAAGATCCGCGTAGAAGGACGACGGCGCCACGCGCTAAGAAGCCGTCCGCGAAGCGCGCCCCGACGC AGCCCAGCAGGACCAGGGCCCACGCGGAAAGCTGCGGCCCGCAAAGGGGGGCTCGATCGCGGCGGGCGGA GCGTGACGGGGACACCACGGAGAAGCCACGTGCCCCAGGGCCCCGAGTGCATCCAGCAAGGGCCACTGAG CTCACCAAAGATGCACAGCCCTCGGCCATGGACGCGGCAGGAGCCACCGCGCGGCCTGCCGTCCGGGTGC CCCAGCAGCAGGCCATCCTGGATCCGGAGCTGCCCGCCGTACGGGAGCCCCAGCCGCCCGCGGATCCCGA GGCGCGGAAAGTCGTAAGGGGACCTAGCCACAGAAGGGGCGCGCGCTCCACCGGGCAGCCCAGAGCGCCG CGAGGGTCCAGGAAGGAACCGGACAAGCTAAAGAAGGTGCTGGACAAATTGAGATTGAAACGCAAAGATA TCTCGGAGGCGGCCGAGACGGTGAATAAAGTTGTGGAACGCCTGCTGCGCAGAATGCAGAAACGGGAGTC GGAGTTCAAAGGTGTGGAGCAGCTGAACACTGGCAGCTACTATGAACATGTGAAGATTTCTGCTCCTAAT GAATTTGATGTTATGTTTAAACTGGAAGTCCCCAGGATTGAGCTACAAGAATATTATGAAACAGGTGCTT TTTATCTTGTGAAATTCAAAAGAATTCCACGAGGAAATCCGCTGAGTCATTTCTTAGAAGGGGAAGTATT ATCAGCTACCAAGATGCTGTCAAAGTTTAGGAAAATCATTAAAGAAGAAGTTAAAGAAATCAAAGATATA GATGTCAGTGTGGAGAAGGAAAAACCAGGAAGCCCTGCTGTAACACTTCTTATCAGGAACCCTGAAGAAA TCTCTGTGGATATAATTCTGGCTTTGGAGTCAAAAGGCAGCTGGCCTATTAGTACCAAAGAAGGACTACC TATTCAAGGCTGGCTGGGCACAAAAGTGAGGACCAATCTAAGACGAGAGCCGTTTTATCTCGTACCCAAG AATGCAAAGGATGGAAATAGTTTTCAAGGAGAGACCTGGCGCCTCTCTTTCTCTCACACTGAAAAGTACA TTTTGAATAATCACGGGATAGAGAAAACATGCTGTGAATCTTCCGGAGCAAAATGCTGCAGAAAAGAATG TTTAAAATTAATGAAATACCTTTTGGAACAGTTGAAAAAAGAGTTTCAAGAGCTGGATGCATTCTGTTCC TACCATGTGAAAACTGCCATCTTTCACATGTGGACCCAGGACCCGCAGGACAGTCAGTGGGACCCCAGGA ACCTCAGCTCCTGCTTCGATAAGTTGTTAGCATTCTTTCTTGAGTGCCTCAGGACAGAGAAACTGGATCA TTATTTTATTCCAAAGTTCAATCTATTCTCTCAAGAACTAATTGACCGAAAAAGTAAAGAATTTCTATCG AAGAAAATTGAATATGAAAGAAATAATGGGTTTCCAATTTTTGACAAGCTT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR213022 protein sequence
Red=Cloning site Green=Tags(s) MEDPRRRTTAPRAKKPSAKRAPTQPSRTRAHAESCGPQRGARSRRAERDGDTTEKPRAPGPRVHPARATE LTKDAQPSAMDAAGATARPAVRVPQQQAILDPELPAVREPQPPADPEARKVVRGPSHRRGARSTGQPRAP RGSRKEPDKLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLNTGSYYEHVKISAPN EFDVMFKLEVPRIELQEYYETGAFYLVKFKRIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDI DVSVEKEKPGSPAVTLLIRNPEEISVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPK NAKDGNSFQGETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKKEFQELDAFCS YHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECLRTEKLDHYFIPKFNLFSQELIDRKSKEFLS KKIEYERNNGFPIFDKL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_173386 |
| ORF Size | 1524 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_173386.2 |
| RefSeq Size | 4090 bp |
| RefSeq ORF | 1524 bp |
| Locus ID | 214763 |
| UniProt ID | Q8C6L5 |
| MW | 58.2 kDa |
| Gene Summary | The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC217197 | MB21D1 (untagged) - Mouse Mab-21 domain containing 1 (Mb21d1), (10ug) |
CNY 6,560.00 |
|
| MG213022 | MB21D1 (tGFP-tagged) - Mouse Mab-21 domain containing 1 (Mb21d1), (10ug) |
CNY 7,272.00 |
|
| MR213022L3 | Lenti ORF clone of-áMB21D1-á(Myc-DDK-tagged) - Mouse Mab-21 domain containing 1 (Mb21d1) |
CNY 8,072.00 |
|
| MR213022L4 | Lenti ORF clone of-áMB21D1-á(mGFP-tagged) - Mouse Mab-21 domain containing 1 (Mb21d1) |
CNY 8,072.00 |
