Grin2c (NM_010350) Mouse Tagged ORF Clone

CAT＃: MR222676

  • TrueORF®

Grin2c (Myc-DDK-tagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c)

ORF Plasmid: DDK tGFP

Datasheet
SDS
Plasmid Map

  "NM_010350" in other vectors (4)

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Mouse Protein / Lysate Request

CNY 8,632.00

货期*
现货
规格
    • 10 ug
Cited in 1 publication.

Product images

经常一起买 (5)
PS100001
pCMV6-Entry, mammalian vector with C-terminal Myc- DDK Tag, 10ug
    • 10 ug

CNY 5,420.00

添加到购物车
CC100003
DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

暂停销售
PRIMER
Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

添加到购物车
TA592569S
DDK Rabbit monoclonal antibody, recognizing both N- and C-terminal tags
    • 30 ul

CNY 300.00

添加到购物车

【特别福利】购一抗正装产品，免费领10ul抗体试用装

TA309199
Rabbit Anti-NMDA NR2C Subunit (Ser1096) Antibody (Phospho-Specific)
    • 100 ul

CNY 5,643.00

添加到购物车

Specifications

Product Data
Type Mouse Tagged ORF Clone
Tag Myc-DDK
Synonyms GluN2C; NMDAR2C; NR2C
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MR222676 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGGTGGAGCCCTGGGGCCCGCCCTGCTTCTCACTTCACTCCTTGGTGCTTGGGCAGGGCTGGGCGCAG
GGCAGGGAGAACAGGCCGTGACCGTGGCGGTGGTGTTTGGCAGCTCTGGGCCACTGCAGGCCCAGGCCCG
GACTCGTCTCACCCCGCAGAACTTCCTGGACTTGCCTCTGGAGATCCAGCCACTCACCATCGGGGTCAAC
AATACCAACCCCAGCAGCATCCTCACCCAAATCTGTGGGCTCCTGGGTGCCGCCCGAGTCCACGGCATCG
TCTTTGAGGACAACGTGGACACTGAGGCCGTGGCTCAGCTGCTGGATTTCGTCTCCTCTCAGACCCACGT
GCCCATCCTCAGCATCAGTGGAGGTTCTGCTGTGGTCCTCACCCCCAAGGAGCCAGGCTCCGCCTTTCTA
CAGCTGGGCGTGTCCCTGGAGCAGCAGCTGCAGGTGCTGTTCAAGGTGCTGGAGGAATACGACTGGAGCG
CGTTCGCTGTCATCACCAGCCTGCACCCGGGCCACGCGCTCTTCCTCGAGGGCGTGCGCGCCGTCGCCGA
CGCCAGCTACCTGAGCTGGCGGCTGCTGGACGTGCTCACGCTGGAGCTGGGCCCCGGTGGGCCGCGAGCG
CGCACTCAGCGCTTACTGCGCCAGGTCGACGCCCCGGTGCTGGTGGCCTACTGCTCCCGTGAAGAGGCGG
AGGTGCTCTTCGCGGAGGCTGCACAGGCTGGCTTGGTGGGACCCGGTCACGTGTGGTTAGTACCTAATCT
GGCGCTGGGAAGCACCGACGCTCCCCCTGCAGCCTTCCCAGTGGGCCTCATCAGTGTGGTCACCGAGAGT
TGGCGCCTTAGCCTACGCCAGAAAGTCCGCGACGGTGTAGCCATTCTGGCCCTCGGTGCCCACAGCTACC
GACGCCAGTACGGTACCCTTCCAGCCCCGGCTGGAGACTGCCGAAGCCACCCAGGACCCGTCAGCCCTGC
CAGGGAGGCTTTCTACAGGCATCTGCTGAATGTCACCTGGGAAGGCCGAGACTTCTCTTTTAGCCCTGGT
GGGTACCTGGTCCAGCCCACAATGGTTGTGATCGCTCTCAACCGGCATCGCCTCTGGGAGATGGTGGGAC
GGTGGGATCATGGGGTCCTGTACATGAAGTATCCAGTATGGCCTCGCTACAGCACTTCTCTGCAGCCTGT
GGTGGACAGCCGGCACCTGACAGTGGCCACACTGGAAGAAAGGCCTTTTGTCATTGTGGAGAGCCCTGAC
CCTGGCACAGGTGGCTGTGTTCCCAACACTGTGCCCTGCCGTAGACAGAGCAACCACACCTTCAGCAGCG
GGGATATAACCCCCTACACCAAGCTCTGTTGTAAGGGCTTCTGCATCGACATCCTCAAGAAGCTGGCCAA
GGTGGTCAAGTTCTCCTACGACTTGTACCTGGTGACCAACGGCAAGCACGGCAAGAGGGTTCGTGGTGTG
TGGAATGGTATGATCGGTGAGGTATACTACAAGCGGGCAGACATGGCCATCGGCTCCCTCACCATCAATG
AAGAGCGCTCAGAGATTATAGACTTCTCTGTGCCTTTTGTGGAGACCGGCATCAGTGTGATGGTGGCAAG
GAGCAACGGCACCGTCTCCCCCTCGGCTTTTCTGGAGCCCTACAGCCCTGCCGTGTGGGTGATGATGTTT
GTAATGTGCCTCACGGTGGTTGCCATCACTGTCTTCATGTTCGAGTATTTCAGCCCTGTCAGCTACAACC
AGAATCTCACCAAGGGCAAGAAGTCAGGTGGACCATCCTTCACCATTGGCAAGTCCGTGTGGTTGCTGTG
GGCACTGGTCTTCAACAACTCTGTTCCCATCGAGAACCCCCGGGGCACCACCAGCAAGATCATGGTCCTG
GTGTGGGCCTTCTTCGCTGTCATCTTCCTCGCTAGCTACACGGCCAATCTGGCAGCCTTCATGATCCAGG
AACAATACATCGACACTGTGTCGGGCCTTAGTGACAAGAAGTTTCAGCGGCCTCAAGACCAATACCCACC
CTTCCGTTTTGGCACGGTACCTAATGGCAGCACAGAGAGGAACATTCGTAGCAACTATCGTGACATGCAC
ACTCACATGGTCAAGTTCAACCAGCGCTCGGTGGAGGATGCTCTCACAAGCCTGAAGATGGGGAAGCTGG
ACGCCTTCATCTATGATGCCGCCGTCCTCAACTACATGGCGGGCAAGGACGAAGGCTGCAAGCTGGTCAC
CATTGGGTCTGGCAAAGTCTTTGCCACCACTGGCTATGGCATTGCCATGCAGAAAGACTCCCACTGGAAG
CGGGCCATAGACCTGGCGCTCCTGCAGTTCCTGGGGGATGGGGAGACACAGAAGTTGGAGACAGTGTGGC
TCTCAGGGATCTGCCATAACGAGAAGAACGAGGTGATGAGCAGCAAGCTGGACATTGACAACATGGCGGG
CGTCTTCTACATGCTGTTGGTGGCCATGGGGCTGGCCCTTCTGGTCTTTGCCTGGGAGCACCTGGTCTAC
TGGAAACTTCGACACTCAGTGCCCAGCTCATCCCAGCTGGACTTCCTGCTGGCTTTCAGCAGGGGCATCT
ACAGCTGCTTCAACGGGGTACAGAGCCTTCCGAGCCCTGCGCGGCCGCCCAGCCCGGACCTTACAGCAGG
CTCAGCCCAGGCCAATGTGCTGAAGATGCTGCAGGCGGCTCGAGACATGGTGAGCACAGCGGACGTGAGC
GGCTCTTTGGACCGCGCCACTCGTACCATCGAGAACTGGGGCAACAATCGCCGCGCGCCTGCTCCCACCA
CCTCCGGCCCGCGGTCATGCACCCCGGGTCCTCCGGGACAACCGAGTCCCAGCGGCTGGCGGCCTCCCGG
TGGGGGCCGCACCCCGCTAGCGCGCCGGGCCCCGCAGCCTCCCGCTCGCCCCGCGACCTGCGCAGGGTCG
CCTCAGCCCGACGTGTCCCGAGCATCCTGCAGGCACGCTTGGGATGCGCGGTGGCCAGTGCGAGTCGGGC
ATCAGGGATCGCACCTCTCGGCCTCCGAGCGGCGCGCGCTCCCGGAGCGCTCCCTGTTGCACGCGCACTG
CCACTACAGTTCCTTCCCTCGAGCAGAGAGGTCAGGGCGCCCATTTCTCCCGCTATTCCCGGAGCCCCCG
GAGCCCGACGACCTGCCGCTGCTCGGGCCGGAACAGCTGGCTCGGCGGGAGGCTCTGCTGCGCGCGGCCT
GGGCCAGGGGCCCGCGCCCTCGGCACGCTTCCCTGCCCAGCTCCGTGGCAGAAGCCTTCACTCGATCCAA
CCCTCTGCCTGCCAGGTGTACCGGTCACGCCTGCGCTTGCCCATGTCCCCAAAGCCGGCCATCCTGCCGG
CACGTGGCTCAAACACAGTCGTTGCGGCTGCCATCCTACCGGGAGGCCTGTGTGGAGGGCGTGCCAGCAG
GGGTGGCCGCCACCTGGCAGCCCAGACAGCATGTCTGCCTGCACACCCATACCCACCTGCCGTTCTGCTG
GGGGACTGTCTGCCGTCACCCTCCACCCTGTTCCAGCCACAGTCCCTGGCTCATTGGAACTTGGGAGCCT
CCATCACACAGAGGCAGGACCCTGGGGCTAGGTACAGGCTACAGGGACAGTGGGGTGCTAGAAGAGGTCA
GCAGGGAAGCTTGTGGGACACAAGGGTTTCCAAGGTCCTGCACCTGGAGGCGGATCTCCAGCCTGGAATC
AGAAGTG

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
>MR222676 protein sequence
Red=Cloning site Green=Tags(s)

MGGALGPALLLTSLLGAWAGLGAGQGEQAVTVAVVFGSSGPLQAQARTRLTPQNFLDLPLEIQPLTIGVN
NTNPSSILTQICGLLGAARVHGIVFEDNVDTEAVAQLLDFVSSQTHVPILSISGGSAVVLTPKEPGSAFL
QLGVSLEQQLQVLFKVLEEYDWSAFAVITSLHPGHALFLEGVRAVADASYLSWRLLDVLTLELGPGGPRA
RTQRLLRQVDAPVLVAYCSREEAEVLFAEAAQAGLVGPGHVWLVPNLALGSTDAPPAAFPVGLISVVTES
WRLSLRQKVRDGVAILALGAHSYRRQYGTLPAPAGDCRSHPGPVSPAREAFYRHLLNVTWEGRDFSFSPG
GYLVQPTMVVIALNRHRLWEMVGRWDHGVLYMKYPVWPRYSTSLQPVVDSRHLTVATLEERPFVIVESPD
PGTGGCVPNTVPCRRQSNHTFSSGDITPYTKLCCKGFCIDILKKLAKVVKFSYDLYLVTNGKHGKRVRGV
WNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMF
VMCLTVVAITVFMFEYFSPVSYNQNLTKGKKSGGPSFTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVL
VWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQRPQDQYPPFRFGTVPNGSTERNIRSNYRDMH
THMVKFNQRSVEDALTSLKMGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWK
RAIDLALLQFLGDGETQKLETVWLSGICHNEKNEVMSSKLDIDNMAGVFYMLLVAMGLALLVFAWEHLVY
WKLRHSVPSSSQLDFLLAFSRGIYSCFNGVQSLPSPARPPSPDLTAGSAQANVLKMLQAARDMVSTADVS
GSLDRATRTIENWGNNRRAPAPTTSGPRSCTPGPPGQPSPSGWRPPGGGRTPLARRAPQPPARPATCAGS
PQPDVSRASCRHAWDARWPVRVGHQGSHLSASERRALPERSLLHAHCHYSSFPRAERSGRPFLPLFPEPP
EPDDLPLLGPEQLARREALLRAAWARGPRPRHASLPSSVAEAFTRSNPLPARCTGHACACPCPQSRPSCR
HVAQTQSLRLPSYREACVEGVPAGVAATWQPRQHVCLHTHTHLPFCWGTVCRHPPPCSSHSPWLIGTWEP
PSHRGRTLGLGTGYRDSGVLEEVSREACGTQGFPRSCTWRRISSLESEV

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Restriction Sites SgfI-MluI      Cloning Scheme for this gene      Plasmid Map     
ACCN NM_010350
ORF Size 3720 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_010350.2, NP_034480.2
RefSeq Size 4895 bp
RefSeq ORF 3720 bp
Locus ID 14813
UniProt ID Q01098
MW 135.4 kDa
Gene Summary Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:1377365). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:1377365). Plays a role in regulating the balance between excitatory and inhibitory activity of pyramidal neurons in the prefrontal cortex (PubMed:27922130). Contributes to the slow phase of excitatory postsynaptic current, long-term synaptic potentiation, and learning (PubMed:8987814).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

The use of this cDNA Clones has been cited in the following citations:
Subunit-specific effects of poricoic acid A on NMDA receptors ,Lee, J;Kim, C;Yeom, HD;Nguyen, KVA;Eom, S;Lee, S;Jung, JH;Lee, JH;Kim, SH;Kim, IK;Lee, JH;, Pharmacol Rep ,PubMed ID 32048268 [GRIN2C]

Other Versions

SKU Description Size Price
MC224027 Grin2c (untagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c), (10ug)
    • 10 ug

CNY 15,870.00

MG222676 Grin2c (tGFP-tagged) - Mouse glutamate receptor ionotropic NMDA2C (epsilon 3) (Grin2c), (10ug)
    • 10 ug

CNY 10,550.00

MR222676L3 Lenti ORF clone of Grin2c (Myc-DDK-tagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c)
    • 10 ug

CNY 11,500.00

MR222676L4 Lenti ORF clone of Grin2c (mGFP-tagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c)
    • 10 ug

CNY 11,500.00

You may also need
plasmid icon Empty Vector
protein iconDDK/Flag Antibody

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Expression Plasmids
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CRISPR
RNAi
Proteins
Antibodies
相关产品 (9)

PS100001

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    • 10 ug

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MR222676L4V

Lenti ORF particles, Grin2c (GFP-tagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c), 200ul, >10^7 TU/mL

    • 200 ul

CNY 19,950.00 暂停销售

MR222676L3

Lenti ORF clone of Grin2c (Myc-DDK-tagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c)

    • 10 ug

CNY 11,500.00

MR222676L3V

Lenti ORF particles, Grin2c (Myc-DDK-tagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c), 200ul, >10^7 TU/mL

    • 200 ul

CNY 17,955.00 暂停销售

MG222676

Grin2c (tGFP-tagged) - Mouse glutamate receptor ionotropic NMDA2C (epsilon 3) (Grin2c), (10ug)

    • 10 ug

CNY 10,550.00

MC224027

Grin2c (untagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c), (10ug)

    • 10 ug

CNY 15,870.00

MR222676L4

Lenti ORF clone of Grin2c (mGFP-tagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c)

    • 10 ug

CNY 11,500.00

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