Stab2 (NM_138673) Mouse Tagged ORF Clone

Specifications

Product Data
Type	Mouse Tagged ORF Clone
Tag	Myc-DDK
Synonyms	FEEL-2; FELL; MFEEL-2; STAB-2
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	ORF Nucleotide Sequence (showhide) >MR223866 representing NM_138673 Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCAAGGAGCAAGCTTCTCCTCGGCAAGCTGCTGCCTTTAATCCTCATCTTCCTGGGGTTGCTTGTGC AAAATGCCTGCTCCCCAACTGAAGCCCCAGAACTGACAAAGAGATGTGATAAGAAGTCTACTCTAACCAT CAAGACGGAGTGCCAGTCCTGCTCGGTTAACATTGCAGTCAAGTGTCCAGACGGCTACATCAAGATTACC AATGGCACTGTCGGGGTTCGAGATTGCAGGTATTCGCTTAAAATCCAGTCCTACGTCCTGGATATCCCTG GATGCCGCCATATCTGTAGGAAGGATTACCTGCAACCTCAATGTTGTCCAGGACACTGGGGCCCAGACTG CATGGAGTGTCCAGGAGGAGCAAGGGCACCGTGTGGTGGCAGGGGTGTTTGTGATGAAGGCATGGAAGGA ACCGGAAGCTGCTCCTGCCGGGCAGGCTTTCGTGGAACAGCCTGTGAGAACTGTGCTGCTGAAGACGTTT TTGGTCCCAATTGTTCAGCAGTGTGCAGTTGTGTCCATGGTGTGTGCAACAGCGGGATCAGTGGTGACGG AACTTGTGAGTGCTTGTCTGCGTACAGGGGGCCCAGGTGTGACAAGCCCATCCCTGAGTGTGCAGCCTTG CTCTGCCCAGAAAACTCCAGATGCTCACCTTCCAGCAAAGACGAAACCAAACTCCAGTGCAAATGCCTTC CCAGTTACAAAGGGGACGGCCAGACCTGCAAGCCCATCAACCCATGTTTAAAAAACGTCTGCCACCCTCA CGCAAGTTGTTCCTACCTGGGACCAAATCGGCACAGTTGTGTATGCCAAAAAGGCTACCAAGGAGATGGT CAAGTGTGTCTGCCAGTGGACCCCTGCCAAACCAGCTATGGAAACTGCCCTACAAAGTCTACGGTGTGCA GATATGATGGGCCTGGACAGTCTCACTGCGAGTGTAAAGAACATTACCGAAATTTTGTACCTGGAGTGGG GTGCAGTATGACGGACATCTGTGAATCAAAAAACCCATGTCATAAGAATGCGAACTGCAGCACAGTCTCA CCAGGCCAAACCCAATGCACTTGCCAGAAAGGTTATGTGGGTGATGGCCTGAACTGCTATGGAAACATCA TGCAGAGACTCAGAGAATTAAATACTGAACCCAGAGGAATGTGGCAAGGACAGCTGACTTCCTTCATCTC AATCCTGGACAGAACTTATGCCTGGCCACTGAGCAACCTGGGACCCTTCACCGTGCTGCTGCCCTCAGAC AAGGGACTAAAAGGGGTTGATGTAAAGGAGCTCTTAATGGACAAAGAGGCTGCTCGGTACTTTGTGAAGC TCCACATCATTGCTGGGCAAATGAGCACGGAGCAGATGTATAACTTGGACACCTTCTATACCTTGACGGG AAAGTCAGGGGAAATCATCAACAAGGATAAGGACAATCAACTAAAGCTCAAACTTTATGGAAGCAAAATA GTGCAAATTATCCAGGGGAACATAGTTGCTTCAAATGGGCTTGTGCATATCCTCGACAGAGCGATGGACA AGATAGAGCCCACACTTGAGAGCAACCCCCAGCAAACCATTATGACAATGCTACAACCAAGATATGGCAA GTTCAGATCTTTGCTAGAGAAAACCAATGTTGGACAAGCCCTGGAGAAGGGTGGTATTGATGAGCCATAC ACCATTTTTGTTCCAAGTAATGAAGCATTGAGTAATATGACGGCTGGTGTCCTCGATTACCTCCTGTCTC CAGAGGGCTCTCGGAAACTTCTGGAACTCGTCAGATACCACATTGTTGCATTTACCCAGCTGGAAGTGGC TACTCTGGTTTCCACACTTCACATCCGAAGCATGGCCAACCAGATCATCACATTTAACATAAGCAGCAAA GGGCAGATTCTGGCAAACAACGTGGCCGTGGATGAAACCGAGGTCGCTGCCAAAAACGGCCGAATTTACA CACTGACCGGAGTTCTCATTCCTCCCTCCATCCTCCCGATCCTTCCCCACCGATGCAATGAAACAAAGAG AGAGATGAAACTGGGCACTTGCGTGAGGTGTTTCATGAAAAACTGGAGCAAATGTCCTACTAACTCGGAG CCCACGGCAATCTTCACAAACAAGTGTTTCTATGGCAGCAGAGCATGGAACCTGAAAATTGGTTGTGCCC GATATTGTGATGTGACTGTGGAGATACCAAGATGCTGTAAAGGTTTCTTCGGACCTGACTGCAACCCATG TCCAGGAGGCTTCATGAATCCGTGTTCTGGAAATGGGCAGTGCATAGACGGCCTCGGTGGCAATGGGACC TGCATCTGTGAGGATGGCTTCCAAGGTTCCAGGTGTCAGTTCTGCTCCAAACCCAACAGATATGGACCTC AGTGTAACAGAACCTGCCAGTGTGTTCATGGAATATGTGATAACAGACTGGACAGCGATGGATCCTGCCT GCCAGGAACATGCCGAGAGGGCACAGCTGGGAGGTTCTGTGACAAGCAGACGTCAGCCTGTGGGCCCTAT ATGCAATTCTGTCACATCCATGCCACCTGTGAATACAGCAATGAGACAGCCAGCTGTGTCTGCAATGACG GCTATGAAGGAGATGGAACTCTCTGTTCTAAGAAGGACCCTTGCCTGGGATCGACCTCCAGAGGAGGATG TAGTCCTAACGCAGAATGCATCCAAGCTAGCACGGGGACATACAGTTGTGTGTGCCAGCGGGGCTGGACA GGGAACGGAAGAGACTGTGTGGAGATCAACAGCTGCCTGCTGCCTAGCTCCGGAGGCTGCCATGACAACG CCACCTGTTTATATGTAGGCCCTGGGCAGAATGAATGTGAATGCAAGAAAGGATTTCGAGGAAACGGAAT TGATTGTGAACCTATCATTTCATGCTTGGAACAAATAGAGAAATGTCACCCCCTGGCCACCTGTCAATAT ACTTTGTCTGGTGTTTGGAGCTGTGTTTGCCAAGAGGGCTATGAAGGAAATGGTGTCCTGTGCTATGGAA ATGTGCTCATGGAACTGTCGTTTCTCTCTGAAGCAGCTGTATTTTACCAGTGGATCAATAATGCTTCTCT GCAGTCCATGCTGTCTGCCACCTCGAATCTCACTGTCCTCGTGCCATCCCTGCAAGCCATCAAGGACATG GACCAGAATGAAAAAAGCTTCTGGTTGTCACGGAACAACATTCCAGCCCTGATAAAATACCACACACTAC TAGGCACATACAGAGTGGCTGATCTGCAGACTCTGCCATCCTCTCACATGCTAGCGACATCCTTGCAGGG AAGCTTCCTTCGCCTGGACAAGGCAGATGGGAATATCACAATTGAGGGGGCATCCTTTGTGGATGGTGAC AATGCAGCCACAAACGGGGTGGTCCACATCATCAACAAGGTGCTAATCCCCCAAAGAGGTCTAACTGGCT CCTTACCCAGTCTACTCACCCGTCTGGAACAGATGCCTGACTATTCCATCTTCCGGGGCTACATCATTCA TTACAATCTGGCAAGTGCAATCGAGGCTGCAGATGCTTATACTGTATTTGTGCCAAACAATGAAGCCATC GAAAGTTATATCAGGGAGAAGAAAGCCACCTCTCTAAAGGAAGACATTCTTCAATACCACGTGGTCCTGG GGGAAAAGCTCCTGAGGAATGACTTGCACAACGGCATGCACCGAGAGACGATGCTGGGCTTCTCCTACCT CCTCGCCTTCTTTCTCCACAATGACCAGCTGTATGTAAATGAAGCTCCAATAAACTACACCAATGTGGCC ACTGACAAGGGAGTGATCCATGGTCTGGAGAAAGTTCTGGAAATCAAGAAGAATAGGTGTGACAATAATG ACACCATTATTGTGAGAGGGAAGTGTGGAAAGTGTTCCCAGCAAACACTCTGCCCGCTCGAGACAAAACC ACTTAGTGAGACGAGGAAATGCATCTATTCCGTTTACTTCATGGGGAAGAGATCCATTTTCATCGGGTGC CAGCTACAGTGTGTGAGAACCATCATTACAAGTGCATGCTGTGCTGGCTTCTTTGGCCCACAATGCCAAG CCTGCCCTGGGAAAGGTCAGAATGTGTGCTCTGGGAATGGCTTCTGTCTGGACGGCGTGAATGGCACTGG CACATGCGAGTGCGAGCAGGGCTTCAATGGGACGGCCTGTGAGACCTGCACAGAGGGGAAGTATGGTATT CACTGTGACCAAGCATGCTCTTGTGTCCATGGGAGATGTAACCAAGGTCCCTCGGGAGATGGCTCCTGTG ACTGCGATGTCGGCTGGCGAGGAGTGAAGTGTGACAGCGAGATCACAACAGACAACTGCAATGGGACCTG CCACACCAGTGCCAACTGCCTTCTCGATCCAGATGGCAAAGCCTCGTGCAAATGTGCGGCAGGATTCCAA GGGAACGGAACGGTCTGCACAGCCATCAATGCCTGTGAGATCAGCAATGGAGGGTGCTCTGCCAAGGCTG ACTGTAAGAGAACCATCCCAGGAAGCCGGGTGTGTGTGTGCAAGGCAGGCTATACCGGCGACGGCATCGT GTGCCTCGAAATCAACCCGTGTTTGGAGAACCACGGCGGCTGTGACAGGCATGCAGAGTGCACGCAGACA GGGCCCAACCAGGCCGTCTGTAACTGCTTGCCCAAGTACACTGGAGATGGAAAGGTCTGCACACTCATCA ACGTCTGCTTAACTAATAACGGCGGCTGCAGTCCATTTGCCTTCTGCAATCACACAGAACAAGATCAAAG GACATGTACCTGCAAGCCAGACTACACGGGTGATGGAATCGTCTGCCGTGGCAGCATCCATTCGGAACTT CCAAAGAATCCCTCAACGTCCCAGTATTTCTTCCAGTTGCAGGAGCATGCTGTCCAAGAGCTTGCTGGAC CTGGCCCCTTCACCGTGTTTGTGCCTTCATCTGACTCCTTCAACAGTGAGTCCAAGCTTAAAGTCTGGGA TAAACAGGGCCTCATGTCCCAGATTCTACGGTATCACGTGGTGGCCTGCCAGCAGCTACTGCTGGAGAAC CTAAAGGTGATCACGAGTGCCACAACCCTCCAAGGAGAGCCAATTTCCATCTCTGTCTCTCAGGACACTG TGCTCATAAACAAGAAGGCGAAGGTTCTGTCCAGTGACATTATCAGCACCAACGGAGTCATCCACGTCAT AGACACATTGTTGTCTCCCCAAAACTTGCTTATCACCCCCAAAGGTGCCTCCGGCAGGGTTCTGCTAAAC CTTACTACAGTGGCAGCAAACCATGGATATACCAAATTCAGCAAGTTGATACAGGACTCAGGCTTGCTGA AAGTCATCACTGACCCCATGCATACCCCAGTCACTCTCTTCTGGCCTACGGACAAAGCCCTCCAAGCCTT GCCTCAGGAGCAGCAGGACTTCCTGTTCAATGAAGACAACAAAGACAAGCTGAAGGCATACCTGAAGTTC CACGTGATCCGAGATACCATGGCTTTAGCTTCAGACCTCCCCAGGTCTGCTTCCTGGAAGACCCTGCAGG GTTCCGAGCTGAGTGTGAGGTGTGGAACTGGCAGTGATGTCGGAGAGCTCTTTCTAAATGGACAAATGTG CAGGATTATACAGCGGAGACTCTTGTTTGACGGAGGTGTGGCCTATGGCATTGACTGCCTGCTAATGGAT CCTACCGAAGGTGGCCGATGTGACACTTTTACTACCTTCAATATTCCGGGGGAATGTGGGAGCTGTTTCT CCACTCCCAGATGCCCACTACAGAGCAAACCAAAGGGTGTGAGGAAGAAGTGTATCTACAACCCGTTACC TTTCAGGAGGGATGTGGAAGGCTGTCAGAACCTGTGCACCCTGGTGGTCCATGTCCCGCGGTGCTGCAGT GGTTACTTCATGCCAGACTGTCAGGCCTGCCCTGGAGGACCAGACACACCGTGTAACAACCGGGGCATGT GTTATGATCAGTACAAACCCACAGGACAGTGCCAATGTCATACTGGTTTCAACGGGACAGCCTGTGAGCT CTGCTTGCCTGGGAGATTTGGTCCTGACTGTCAACCCTGTGGCTGCTCTGAGCATGGGCAGTGTGACGAG GGGATCACAGGCTCCGGGCAGTGCCTCTGTGAAGCAGGGTGGACAGGCCGCTTCTGTGATGCTCCCACAG TTGTGATTCCAGTGTGCATACCTGCTTGTTCCATGCACGCAACCTGTATGGAGAACAACACATGTGTGTG TAACTTGAATTACGAAGGTGACGGAATCACATGCACAGTCGTGGATTTCTGCAAACAGAACAATGGGGGC TGTGCGAAGGTCGCCAAGTGCTCCCAGAAGGGCACACAAGTCTCCTGCAGCTGCCAGAAGGGCTACAAGG GGGATGGCCACAGCTGCACAGAGATAGACCCCTGTGCAAACGGTGTCAATGGTGGATGTCATGAGCATGC TACCTGCAGGATGACGGGCCCAGGCAAGCAGAAGTGTGAATGTAAAAGTCACTATGTCGGGGATGGACGG GACTGTGAGCCCGAACAGCTGCCCCTTGACCGCTGCTTACAGGACAACGGACAATGCCACCCAGATGCCA ACTGTGTGGACCTTCATTTCCAGGACACTACTGTTGGCGTATTCCACCTACGCTCCCCACTGGGCCAGTA CAAACTGACATTTGACAAAGCCAAAGAGGCCTGTGCTAAGGAAGCTGCATCCATAGCCACCTACAACCAG CTCTCCTATGCCCAGAAGGCCAAGTATCACCTCTGCTCAGCTGGCTGGCTGGAGAGTGGGCGGGTTGCCT ACCCCACGATCTACGCCTCTAAGAAATGTGCAAACATTGTGGGGATTGTAGACTACGGAACCAGGACCAA CAAGAGTGAAATGTGGGACGTCTTCTGTTACAGAATGAAAGATGTTAACTGCACCTGCAAGGCAGGCTAC GTGGGCGATGGCTTCTCCTGCAATGGGAACCTGCTGCAAGTCCTCATGTCCTTCCCCTCACTCACGAACT TCCTGACAGAGGTGCTGGTTTTTTCCAGGAGCTCAGCCCAAGGCCGGGCGTTTTTGAAACACCTGACTGA CCTGTCCATCAGTGGCACCCTGTTTGTGCCACAGAACAGTGGGCTACCGAAAAATAAGAGCCTGTCTGGG CGGGACATTGAGCACCACCTCACTAATGTCAACGTCTCCTTTTACGATGACCTTGTCAATGGTACCGTCC TGAAGACTAGGCTGGGAAGCCAACTGCTCATCACCTCCAGCCAGGACCAGCTCCACCAAGAGGCCAGGTT CGTGGATGGAAGAGCCATTCTGCAGTGGGACATCATTGCCTCTAACGGGGTTCTCCATATCATTTCTGAA CCTTTGAAAGCTCCTCCCACGGCCGCAACGGCTGCCCACTCTGGCCTAGGAACAGGCATATTCTGCGCTG TCGTCCTGGTTACTGGTGCGATTGCTCTGGCTGCCTACTCCTACTTCCGGCTAAACCAGAGAACAACTGG CTTCCGGCGTTTTGAGTCAGAAGATGACATTGATGCCTTGGCCTTTGGCAAGCAGCAGCCTGAGAGTATC ACAAACCCTTTGTATGAGACCTCAACGCCGGCAGCCCCCGAGCCCTCCTGTGACCCCTTCACCGACTCTG GAGAACGGGAGCTGGAGAACAGTGACCCTCTTGGGGCACTGAGGTCC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA Protein Sequence (showhide) >MR223866 representing NM_138673 Red=Cloning site Green=Tags(s) MARSKLLLGKLLPLILIFLGLLVQNACSPTEAPELTKRCDKKSTLTIKTECQSCSVNIAVKCPDGYIKIT NGTVGVRDCRYSLKIQSYVLDIPGCRHICRKDYLQPQCCPGHWGPDCMECPGGARAPCGGRGVCDEGMEG TGSCSCRAGFRGTACENCAAEDVFGPNCSAVCSCVHGVCNSGISGDGTCECLSAYRGPRCDKPIPECAAL LCPENSRCSPSSKDETKLQCKCLPSYKGDGQTCKPINPCLKNVCHPHASCSYLGPNRHSCVCQKGYQGDG QVCLPVDPCQTSYGNCPTKSTVCRYDGPGQSHCECKEHYRNFVPGVGCSMTDICESKNPCHKNANCSTVS PGQTQCTCQKGYVGDGLNCYGNIMQRLRELNTEPRGMWQGQLTSFISILDRTYAWPLSNLGPFTVLLPSD KGLKGVDVKELLMDKEAARYFVKLHIIAGQMSTEQMYNLDTFYTLTGKSGEIINKDKDNQLKLKLYGSKI VQIIQGNIVASNGLVHILDRAMDKIEPTLESNPQQTIMTMLQPRYGKFRSLLEKTNVGQALEKGGIDEPY TIFVPSNEALSNMTAGVLDYLLSPEGSRKLLELVRYHIVAFTQLEVATLVSTLHIRSMANQIITFNISSK GQILANNVAVDETEVAAKNGRIYTLTGVLIPPSILPILPHRCNETKREMKLGTCVRCFMKNWSKCPTNSE PTAIFTNKCFYGSRAWNLKIGCARYCDVTVEIPRCCKGFFGPDCNPCPGGFMNPCSGNGQCIDGLGGNGT CICEDGFQGSRCQFCSKPNRYGPQCNRTCQCVHGICDNRLDSDGSCLPGTCREGTAGRFCDKQTSACGPY MQFCHIHATCEYSNETASCVCNDGYEGDGTLCSKKDPCLGSTSRGGCSPNAECIQASTGTYSCVCQRGWT GNGRDCVEINSCLLPSSGGCHDNATCLYVGPGQNECECKKGFRGNGIDCEPIISCLEQIEKCHPLATCQY TLSGVWSCVCQEGYEGNGVLCYGNVLMELSFLSEAAVFYQWINNASLQSMLSATSNLTVLVPSLQAIKDM DQNEKSFWLSRNNIPALIKYHTLLGTYRVADLQTLPSSHMLATSLQGSFLRLDKADGNITIEGASFVDGD NAATNGVVHIINKVLIPQRGLTGSLPSLLTRLEQMPDYSIFRGYIIHYNLASAIEAADAYTVFVPNNEAI ESYIREKKATSLKEDILQYHVVLGEKLLRNDLHNGMHRETMLGFSYLLAFFLHNDQLYVNEAPINYTNVA TDKGVIHGLEKVLEIKKNRCDNNDTIIVRGKCGKCSQQTLCPLETKPLSETRKCIYSVYFMGKRSIFIGC QLQCVRTIITSACCAGFFGPQCQACPGKGQNVCSGNGFCLDGVNGTGTCECEQGFNGTACETCTEGKYGI HCDQACSCVHGRCNQGPSGDGSCDCDVGWRGVKCDSEITTDNCNGTCHTSANCLLDPDGKASCKCAAGFQ GNGTVCTAINACEISNGGCSAKADCKRTIPGSRVCVCKAGYTGDGIVCLEINPCLENHGGCDRHAECTQT GPNQAVCNCLPKYTGDGKVCTLINVCLTNNGGCSPFAFCNHTEQDQRTCTCKPDYTGDGIVCRGSIHSEL PKNPSTSQYFFQLQEHAVQELAGPGPFTVFVPSSDSFNSESKLKVWDKQGLMSQILRYHVVACQQLLLEN LKVITSATTLQGEPISISVSQDTVLINKKAKVLSSDIISTNGVIHVIDTLLSPQNLLITPKGASGRVLLN LTTVAANHGYTKFSKLIQDSGLLKVITDPMHTPVTLFWPTDKALQALPQEQQDFLFNEDNKDKLKAYLKF HVIRDTMALASDLPRSASWKTLQGSELSVRCGTGSDVGELFLNGQMCRIIQRRLLFDGGVAYGIDCLLMD PTEGGRCDTFTTFNIPGECGSCFSTPRCPLQSKPKGVRKKCIYNPLPFRRDVEGCQNLCTLVVHVPRCCS GYFMPDCQACPGGPDTPCNNRGMCYDQYKPTGQCQCHTGFNGTACELCLPGRFGPDCQPCGCSEHGQCDE GITGSGQCLCEAGWTGRFCDAPTVVIPVCIPACSMHATCMENNTCVCNLNYEGDGITCTVVDFCKQNNGG CAKVAKCSQKGTQVSCSCQKGYKGDGHSCTEIDPCANGVNGGCHEHATCRMTGPGKQKCECKSHYVGDGR DCEPEQLPLDRCLQDNGQCHPDANCVDLHFQDTTVGVFHLRSPLGQYKLTFDKAKEACAKEAASIATYNQ LSYAQKAKYHLCSAGWLESGRVAYPTIYASKKCANIVGIVDYGTRTNKSEMWDVFCYRMKDVNCTCKAGY VGDGFSCNGNLLQVLMSFPSLTNFLTEVLVFSRSSAQGRAFLKHLTDLSISGTLFVPQNSGLPKNKSLSG RDIEHHLTNVNVSFYDDLVNGTVLKTRLGSQLLITSSQDQLHQEARFVDGRAILQWDIIASNGVLHIISE PLKAPPTAATAAHSGLGTGIFCAVVLVTGAIALAAYSYFRLNQRTTGFRRFESEDDIDALAFGKQQPESI TNPLYETSTPAAPEPSCDPFTDSGERELENSDPLGALRS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Chromatograms	CHROMATOGRAMS Sequencher program is needed, download here.
Restriction Sites	SgfI-MluI      Cloning Scheme for this gene      Plasmid Map
ACCN	NM_138673
ORF Size	7677 bp
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_138673.2, NP_619614.1
RefSeq Size	8152 bp
RefSeq ORF	7680 bp
Locus ID	192188
UniProt ID	Q8R4U0
MW	278 kDa
Gene Summary	Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed short form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.[UniProtKB/Swiss-Prot Function]

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