Heme Oxygenase 1 (HMOX1) (NM_002133) Human Tagged ORF Clone
CAT#: RC200463
HMOX1 (Myc-DDK-tagged)-Human heme oxygenase (decycling) 1 (HMOX1)
ORF Plasmid: tGFP
"NM_002133" in other vectors (7)
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CNY 2,400.00
CNY 4,465.00
Cited in 8 publications. |
CNY 300.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | bK286B10; HMOX1D; HO-1; HSP32 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC200463 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGCGTCCGCAACCCGACAGCATGCCCCAGGATTTGTCAGAGGCCCTGAAGGAGGCCACCAAGGAGG TGCACACCCAGGCAGAGAATGCTGAGTTCATGAGGAACTTTCAGAAGGGCCAGGTGACCCGAGACGGCTT CAAGCTGGTGATGGCCTCCCTGTACCACATCTATGTGGCCCTGGAGGAGGAGATTGAGCGCAACAAGGAG AGCCCAGTCTTCGCCCCTGTCTACTTCCCAGAAGAGCTGCACCGCAAGGCTGCCCTGGAGCAGGACCTGG CCTTCTGGTACGGGCCCCGCTGGCAGGAGGTCATCCCCTACACACCAGCCATGCAGCACTATGTGAAGCG GCTCCACGAGGTGGGGCGCACAGAGCCCGAGCTGCTGGTGGCCCACGCCTACACCCGCTACCTGGGTGAC CTGTCTGGGGGCCAGGTGCTCAAAAAGATTGCCCAGAAAGCCCTGGACCTGCCCAGCTCTGGCGAGGGCC TGGCCTTCTTCACCTTCCCCAACATTGCCAGTGCCACCAAGTTCAAGCAGCTCTACCGCTCCCGCATGAA CTCCCTGGAGATGACTCCCGCAGTCAGGCAGAGGGTGATAGAAGAGGCCAAGACTGCGTTCCTGCTCAAC ATCCAGCTCTTTGAGGAGTTGCAGGAGCTGCTGACCCATGACACCAAGGACCAGAGCCCCTCACGGGCAC CAGGGCTTCGCCAGCGGGCCAGCAACAAAGTGCAAGATTCTGCCCCCGTGGAGACTCCCAGAGGGAAGCC CCCACTCAACACCCGCTCCCAGGCTCCGCTTCTCCGATGGGTCCTTACACTCAGCTTTCTGGTGGCGACA GTTGCTGTAGGGCTTTATGCCATG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC200463 protein sequence
Red=Cloning site Green=Tags(s) MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKE SPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQHYVKRLHEVGRTEPELLVAHAYTRYLGD LSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLN IQLFEELQELLTHDTKDQSPSRAPGLRQRASNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVAT VAVGLYAM TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
Sequencher program is needed, download here. |
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_002133 |
ORF Size | 864 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_002133.3 |
RefSeq Size | 1606 bp |
RefSeq ORF | 867 bp |
Locus ID | 3162 |
UniProt ID | P09601 |
Domains | Heme_oxygenase |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Porphyrin and chlorophyll metabolism |
MW | 32.8 kDa |
Gene Summary | Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008] |
Citations (8)
The use of this cDNA Clones has been cited in the following citations: |
---|
Restriction of HIV-1 infection in sickle cell trait
,null,
Blood Advances
,PubMed ID 34496009
[Heme Oxygenase 1]
|
Endothelin-1 as a Mediator of Heme Oxygenase-1-Induced Stemness in Colorectal Cancer: Influence of p53
,Ríos-Arrabal, S;Puentes-Pardo, JD;Moreno-SanJuan, S;Szuba, Á;Casado, J;García-Costela, M;Escudero-Feliu, J;Verbeni, M;Cano, C;González-Puga, C;Martín-Lagos Maldonado, A;Carazo, Á;León, J;,
Journal of Personalized Medicine
,PubMed ID 34199777
[Heme Oxygenase 1]
|
CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity.
,null,
Cell
,PubMed ID 31150623
[Heme Oxygenase 1]
|
Adipocyte-activated oxidative and ER stress pathways promote tumor survival in bone via upregulation of Heme Oxygenase 1 and Survivin
,Herroon, MK;Rajagurubandara, E;Diedrich, JD;Heath, EI;Podgorski, I;,
Sci Rep
,PubMed ID 29311669
[Heme Oxygenase 1]
|
Heme oxygenase-1 mediates BAY 11-7085 induced ferroptosis
,Chang, LC;Chiang, SK;Chen, SE;Yu, YL;Chou, RH;Chang, WC;,
Cancer Lett.
,PubMed ID 29274359
[Heme Oxygenase 1]
|
Evidence of activation of the Nrf2 pathway in multiple sclerosis patients treated with delayed-release dimethyl fumarate in the Phase 3 DEFINE and CONFIRM studies
,Gopal, S;Mikulskis, A;Gold, R;Fox, RJ;Dawson, KT;Amaravadi, L;,
Mult. Scler
,PubMed ID 28156185
[Heme Oxygenase 1]
|
The role of HO-1 in protection against lead-induced neurotoxicity
,Li, X;Ye, F;Li, L;Chang, W;Wu, X;Chen, J;,
Neurotoxicology
,PubMed ID 26542248
[Heme Oxygenase 1]
|
The combined effects of physicochemical properties ofsize-fractionated ambient particulate matter on in vitrotoxicity in human A549 lung epithelial cells
,Akhtar, US;Rastogi, N;McWhinney, RD;Urch, B;,
Toxicology Reports
[Heme Oxygenase 1]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC200463L1 | Lenti ORF clone of Human heme oxygenase (decycling) 1 (HMOX1), Myc-DDK-tagged |
CNY 4,800.00 |
|
RC200463L2 | Lenti ORF clone of Human heme oxygenase (decycling) 1 (HMOX1), mGFP tagged |
CNY 5,890.00 |
|
RC200463L3 | Lenti ORF clone of Human heme oxygenase (decycling) 1 (HMOX1), Myc-DDK-tagged |
CNY 4,800.00 |
|
RC200463L4 | Lenti ORF clone of Human heme oxygenase (decycling) 1 (HMOX1), mGFP tagged |
CNY 4,800.00 |
|
RG200463 | HMOX1 (tGFP-tagged) - Human heme oxygenase (decycling) 1 (HMOX1) |
CNY 4,000.00 |
|
SC128080 | HMOX1 (untagged)-Human heme oxygenase (decycling) 1 (HMOX1) |
CNY 2,400.00 |
|
SC320297 | HMOX1 (untagged)-Human heme oxygenase (decycling) 1 (HMOX1) |
CNY 2,400.00 |
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