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Squalene Epoxidase (SQLE) (NM_003129) Human Tagged ORF Clone
CAT＃: RC202008
SQLE (Myc-DDK-tagged)-Human squalene epoxidase (SQLE)
ORF Plasmid: tGFP
"NM_003129" in other vectors (7)
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CNY 4,272.00
CNY 4,560.00
| Cited in 2 publications. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC202008 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTGGACTTTTCTGGGCATTGCCACTTTCACCTATTTTTATAAGAAGTTCGGGGACTTCATCACTTTGG CCAACAGGGAGGTCCTGTTGTGCGTGCTGGTGTTCCTCTCGCTGGGCCTGGTGCTCTCCTACCGCTGTCG CCACCGAAACGGGGGTCTCCTCGGGCGCCAGCAGAGCGGCTCCCAGTTCGCCCTCTTCTCGGATATTCTC TCAGGCCTGCCTTTCATTGGCTTCTTCTGGGCCAAATCCCCCCCTGAATCAGAAAATAAGGAGCAGCTCG AGGCCAGGAGGCGCAGAAAAGGAACCAATATTTCAGAAACAAGCTTAATAGGAACAGCTGCCTGTACATC AACATCTTCTCAGAATGACCCAGAAGTTATCATCGTGGGAGCTGGCGTGCTTGGCTCTGCTTTGGCAGCT GTGCTTTCCAGAGATGGAAGAAAGGTGACAGTCATTGAGAGAGACTTAAAAGAGCCTGACAGAATAGTTG GAGAATTCCTGCAGCCGGGTGGTTATCATGTTCTCAAAGACCTTGGTCTTGGAGATACAGTGGAAGGTCT TGATGCCCAGGTTGTAAATGGTTACATGATTCATGATCAGGAAAGCAAATCAGAGGTTCAGATTCCTTAC CCTCTGTCAGAAAACAATCAAGTGCAGAGTGGAAGAGCTTTCCATCACGGAAGATTCATCATGAGTCTCC GGAAAGCAGCTATGGCAGAGCCCAATGCAAAGTTTATTGAAGGTGTTGTGTTACAGTTATTAGAGGAAGA TGATGTTGTGATGGGAGTTCAGTACAAGGATAAAGAGACTGGAGATATCAAGGAACTCCATGCTCCACTG ACTGTTGTTGCAGATGGGCTTTTCTCCAAGTTCAGGAAAAGCCTGGTCTCCAATAAAGTTTCTGTATCAT CTCATTTTGTTGGCTTTCTTATGAAGAATGCACCACAGTTTAAAGCAAATCATGCTGAACTTATTTTAGC TAACCCGAGTCCAGTTCTCATCTACCAGATTTCATCCAGTGAAACTCGAGTACTTGTTGACATTAGAGGA GAAATGCCAAGGAATTTAAGAGAATACATGGTTGAAAAAATTTACCCACAAATACCTGATCACCTGAAAG AACCATTCTTAGAAGCCACTGACAATTCTCATCTGAGGTCCATGCCAGCAAGCTTCCTTCCTCCTTCATC AGTGAAGAAACGAGGTGTTCTTCTTTTGGGAGACGCATATAATATGAGGCATCCACTTACTGGTGGAGGA ATGACTGTTGCTTTTAAAGATATAAAACTATGGAGAAAACTGCTAAAGGGTATCCCTGACCTTTATGATG ATGCAGCTATTTTCGAGGCCAAAAAATCATTTTACTGGGCAAGAAAAACATCTCATTCCTTTGTCGTGAA TATCCTTGCTCAGGCTCTTTATGAATTATTTTCTGCCACAGATGATTCCCTGCATCAACTAAGAAAAGCC TGTTTTCTTTATTTCAAACTTGGTGGCGAATGTGTTGCGGGTCCTGTTGGGCTGCTTTCTGTATTGTCTC CTAACCCTCTAGTTTTAATTGGACACTTCTTTGCTGTTGCAATCTATGCCGTGTATTTTTGCTTTAAGTC AGAACCTTGGATTACAAAACCTCGAGCCCTTCTCAGTAGTGGTGCTGTATTGTACAAAGCGTGTTCTGTA ATATTTCCTCTAATTTACTCAGAAATGAAGTATATGGTTCAT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC202008 protein sequence
Red=Cloning site Green=Tags(s) MWTFLGIATFTYFYKKFGDFITLANREVLLCVLVFLSLGLVLSYRCRHRNGGLLGRQQSGSQFALFSDIL SGLPFIGFFWAKSPPESENKEQLEARRRRKGTNISETSLIGTAACTSTSSQNDPEVIIVGAGVLGSALAA VLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGLGDTVEGLDAQVVNGYMIHDQESKSEVQIPY PLSENNQVQSGRAFHHGRFIMSLRKAAMAEPNAKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKELHAPL TVVADGLFSKFRKSLVSNKVSVSSHFVGFLMKNAPQFKANHAELILANPSPVLIYQISSSETRVLVDIRG EMPRNLREYMVEKIYPQIPDHLKEPFLEATDNSHLRSMPASFLPPSSVKKRGVLLLGDAYNMRHPLTGGG MTVAFKDIKLWRKLLKGIPDLYDDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSATDDSLHQLRKA CFLYFKLGGECVAGPVGLLSVLSPNPLVLIGHFFAVAIYAVYFCFKSEPWITKPRALLSSGAVLYKACSV IFPLIYSEMKYMVH TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_003129 |
| ORF Size | 1722 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003129.4 |
| RefSeq Size | 2989 bp |
| RefSeq ORF | 1725 bp |
| Locus ID | 6713 |
| UniProt ID | Q14534 |
| Domains | Monooxygenase |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Metabolic pathways, Steroid biosynthesis |
| MW | 63.9 kDa |
| Gene Summary | Squalene epoxidase catalyzes the first oxygenation step in sterol biosynthesis and is thought to be one of the rate-limiting enzymes in this pathway. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Curcumin sensitizes response to cytarabine in acute myeloid leukemia by regulating intestinal microbiota
,null,
Cancer Chemotherapy and Pharmacology
,PubMed ID 35066694
[Squalene Epoxidase]
|
|
Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target
,Liu, D;Wong, CC;Fu, L;Chen, H;Zhao, L;Li, C;Zhou, Y;Zhang, Y;Xu, W;Yang, Y;Wu, B;Cheng, G;Lai, PB;Wong, N;Sung, JJY;Yu, J;,
Sci Transl Med
,PubMed ID 29669855
[Squalene Epoxidase]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202008L1 | Lenti ORF clone of Human squalene epoxidase (SQLE), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC202008L2 | Lenti ORF clone of Human squalene epoxidase (SQLE), mGFP tagged |
CNY 6,460.00 |
|
| RC202008L3 | Lenti ORF clone of Human squalene epoxidase (SQLE), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC202008L4 | Lenti ORF clone of Human squalene epoxidase (SQLE), mGFP tagged |
CNY 6,460.00 |
|
| RG202008 | SQLE (tGFP-tagged) - Human squalene epoxidase (SQLE) |
CNY 5,040.00 |
|
| SC118174 | SQLE (untagged)-Human squalene epoxidase (SQLE) |
CNY 2,950.00 |
|
| SC324651 | SQLE (untagged)-Human squalene epoxidase (SQLE) |
CNY 2,950.00 |
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