RAIDD (CRADD) (NM_003805) Human Tagged ORF Clone
CAT#: RC202050
CRADD (Myc-DDK-tagged)-Human CASP2 and RIPK1 domain containing adaptor with death domain (CRADD)
ORF Plasmid: tGFP
"NM_003805" in other vectors (6)
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CNY 2,400.00
CNY 3,705.00
CNY 300.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | MRT34; RAIDD |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC202050 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGGCCAGAGACAAACAAGTACTCCGCTCACTTCGCCTGGAGCTGGGTGCAGAGGTATTGGTGGAGG GACTGGTTCTTCAGTACCTCTACCAGGAAGGAATCTTGACGGAAAACCATATTCAAGAAATCAATGCTCA AACCACAGGCCTCCGGAAAACAATGCTCCTGCTGGATATCCTACCTTCCAGGGGCCCTAAAGCATTTGAT ACATTCCTAGATTCCCTACAGGAGTTTCCCTGGGTCAGGGAGAAGCTGAAGAAGGCAAGGGAAGAGGCCA TGACCGACCTGCCTGCAGGTGACAGATTGACTGGGATCCCCTCGCACATCCTCAACAGCTCCCCATCAGA CCGGCAGATTAACCAGCTGGCCCAGAGGCTGGGCCCTGAGTGGGAGCCCATGGTGCTGTCTCTGGGACTG TCCCAGACGGATATCTACCGCTGTAAGGCCAACCACCCCCACAACGTGCAGTCGCAGGTGGTGGAGGCCT TCATCCGTTGGCGGCAGCGCTTCGGGAAGCAGGCCACCTTCCAGAGCCTGCACAACGGGCTGCGGGCTGT GGAGGTGGACCCCTCGCTGCTCCTGCACATGTTGGAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC202050 protein sequence
Red=Cloning site Green=Tags(s) MEARDKQVLRSLRLELGAEVLVEGLVLQYLYQEGILTENHIQEINAQTTGLRKTMLLLDILPSRGPKAFD TFLDSLQEFPWVREKLKKAREEAMTDLPAGDRLTGIPSHILNSSPSDRQINQLAQRLGPEWEPMVLSLGL SQTDIYRCKANHPHNVQSQVVEAFIRWRQRFGKQATFQSLHNGLRAVEVDPSLLLHMLE TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
Sequencher program is needed, download here. |
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_003805 |
ORF Size | 597 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_003805.5 |
RefSeq Size | 1201 bp |
RefSeq ORF | 600 bp |
Locus ID | 8738 |
UniProt ID | P78560 |
Domains | DEATH, CARD |
Protein Families | Druggable Genome |
MW | 22.7 kDa |
Gene Summary | This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC202050L1 | Lenti ORF clone of Human CASP2 and RIPK1 domain containing adaptor with death domain (CRADD), Myc-DDK-tagged |
CNY 4,800.00 |
|
RC202050L2 | Lenti ORF clone of Human CASP2 and RIPK1 domain containing adaptor with death domain (CRADD), mGFP tagged |
CNY 5,890.00 |
|
RC202050L3 | Lenti ORF clone of Human CASP2 and RIPK1 domain containing adaptor with death domain (CRADD), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC202050L4 | Lenti ORF clone of Human CASP2 and RIPK1 domain containing adaptor with death domain (CRADD), mGFP tagged |
CNY 5,890.00 |
|
RG202050 | CRADD (tGFP-tagged) - Human CASP2 and RIPK1 domain containing adaptor with death domain (CRADD) |
CNY 4,000.00 |
|
SC111084 | CRADD (untagged)-Human CASP2 and RIPK1 domain containing adaptor with death domain (CRADD) |
CNY 2,400.00 |