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OMA1 (NM_145243) Human Tagged ORF Clone
CAT＃: RC204507
- TrueORF®
OMA1 (Myc-DDK-tagged)-Human OMA1 homolog, zinc metallopeptidase (S. cerevisiae) (OMA1)
ORF Plasmid: tGFP
"NM_145243" in other vectors (7)
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CNY 3,904.00
CNY 3,990.00
| Cited in 2 publications. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | 2010001O09Rik; DAB1; MPRP-1; MPRP1; peptidase; YKR087C; ZMPOMA1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC204507 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGCTTCATCTGTGGATTGCAGTCTGCTGCTAGAAACCATGTTTTCTTCCGATTTAATTCACTGTCTA ACTGGAGAAAATGTAACACATTAGCATCCACCTCACGGGGCTGTCATCAAGTACAAGTTAACCATATAGT AAATAAGTATCAGGGACTGGGAGTAAATCAGTGTGACAGGTGGAGTTTTCTGCCTGGAAACTTTCATTTT TATAGTACTTTTAACAACAAAAGAACAGGAGGCCTCTCAAGTACCAAAAGTAAGGAAATTTGGAGGATTA CCAGCAAATGTACTGTATGGAATGATGCTTTTTCAAGACAGCTGCTAATAAAAGAAGTTACAGCAGTCCC TAGTCTGTCAGTATTGCATCCTCTAAGCCCTGCTTCCATAAGAGCTATTAGGAATTTCCATACTTCTCCA CGGTTTCAAGCTGCTCCGGTTCCTCTCTTGTTGATGATTCTTAAACCAGTACAGAAGTTATTTGCAATCA TTGTAGGCAGGGGCATAAGGAAATGGTGGCAGGCACTTCCTCCTAACAAGAAGGAAGTAGTTAAAGAAAA TATAAGGAAGAATAAATGGAAGCTATTCCTTGGTTTGAGTAGTTTTGGATTGCTCTTTGTGGTGTTTTAT TTTACTCACCTGGAAGTAAGTCCAATCACAGGAAGGAGCAAGCTACTATTATTGGGGAAAGAACAGTTCA GACTTTTATCGGAACTGGAATATGAAGCATGGATGGAAGAATTTAAAAATGATATGCTAACTGAGAAAGA TGCCCGATACCTGGCTGTTAAAGAAGTGCTTTGTCATCTAATTGAATGCAATAAAGATGTTCCAGGGATC TCTCAGATCAATTGGGTTATTCATGTGGTTGATTCCCCAATTATTAATGCCTTCGTGCTTCCAAATGGAC AAATGTTTGTTTTCACTGGATTTTTAAATAGTGTAACCGATATTCATCAACTTTCTTTCCTTCTGGGCCA TGAAATAGCACATGCAGTACTTGGGCATGCTGCAGAAAAGGCTGGCATGGTTCATTTGTTGGATTTCCTA GGTATGATTTTCCTCACAATGATTTGGGCCATTTGTCCTCGAGATAGCTTGGCACTTTTGTGCCAGTGGA TACAGTCTAAATTGCAGGAGTATATGTTTAATAGACCATACAGCAGAAAATTGGAGGCCGAAGCTGACAA AATTGGACTACTGCTTGCTGCAAAGGCTTGTGCAGACATAAGAGCCAGTTCAGTGTTTTGGCAGCAAATG GAGTTCGTTGATAGCCTGCATGGCCAACCCAAGATGCCAGAATGGTTATCTACACACCCTTCTCATGGCA ATCGAGTTGAGTACTTGGATAGACTTATACCTCAGGCTCTCAAAATTAGAGAGATGTGTAATTGTCCACC ACTGTCTAATCCAGACCCTCGATTACTATTCAAACTCAGCACGAAGCATTTTCTTGAAGAATCAGAGAAA GAAGACCTAAATATCACGAAGAAACAGAAAATGGATACTCTTCCTATTCAAAAACAGGAGCAAATACCAT TAACATACATAGTTGAGAAAAGAACGGGCAGT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC204507 protein sequence
Red=Cloning site Green=Tags(s) MSFICGLQSAARNHVFFRFNSLSNWRKCNTLASTSRGCHQVQVNHIVNKYQGLGVNQCDRWSFLPGNFHF YSTFNNKRTGGLSSTKSKEIWRITSKCTVWNDAFSRQLLIKEVTAVPSLSVLHPLSPASIRAIRNFHTSP RFQAAPVPLLLMILKPVQKLFAIIVGRGIRKWWQALPPNKKEVVKENIRKNKWKLFLGLSSFGLLFVVFY FTHLEVSPITGRSKLLLLGKEQFRLLSELEYEAWMEEFKNDMLTEKDARYLAVKEVLCHLIECNKDVPGI SQINWVIHVVDSPIINAFVLPNGQMFVFTGFLNSVTDIHQLSFLLGHEIAHAVLGHAAEKAGMVHLLDFL GMIFLTMIWAICPRDSLALLCQWIQSKLQEYMFNRPYSRKLEAEADKIGLLLAAKACADIRASSVFWQQM EFVDSLHGQPKMPEWLSTHPSHGNRVEYLDRLIPQALKIREMCNCPPLSNPDPRLLFKLSTKHFLEESEK EDLNITKKQKMDTLPIQKQEQIPLTYIVEKRTGS TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_145243 |
| ORF Size | 1572 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_145243.5 |
| RefSeq Size | 1928 bp |
| RefSeq ORF | 1575 bp |
| Locus ID | 115209 |
| UniProt ID | Q96E52 |
| Protein Families | Druggable Genome, Protease, Transmembrane |
| MW | 60.1 kDa |
| Gene Summary | Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.[UniProtKB/Swiss-Prot Function] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The Role and Regulation of Mitochondrial Dynamics in Cisplatin Resistance in Human Gynecologic Cancer Cells
,Kong, B;,
Thesis
[OMA1]
|
|
p53 is required for cisplatin-induced processing of the mitochondrial fusion protein L-Opa1 that is mediated by the mitochondrial metallopeptidase Oma1 in Gynecologic Cancers
,Kong, B;Wang, Q;Fung, E;Xue, K;Tsang, BK;,
J. Biol. Chem.
,PubMed ID 25112877
[OMA1]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204507L1 | Lenti ORF clone of Human OMA1 homolog, zinc metallopeptidase (S. cerevisiae) (OMA1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204507L2 | Lenti ORF clone of Human OMA1 homolog, zinc metallopeptidase (S. cerevisiae) (OMA1), mGFP tagged |
CNY 5,890.00 |
|
| RC204507L3 | Lenti ORF clone of Human OMA1 homolog, zinc metallopeptidase (S. cerevisiae) (OMA1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204507L4 | Lenti ORF clone of Human OMA1 homolog, zinc metallopeptidase (S. cerevisiae) (OMA1), mGFP tagged |
CNY 5,890.00 |
|
| RG204507 | OMA1 (tGFP-tagged) - Human OMA1 homolog, zinc metallopeptidase (S. cerevisiae) (OMA1) |
CNY 4,370.00 |
|
| SC126516 | OMA1 (untagged)-Human OMA1 homolog, zinc metallopeptidase (S. cerevisiae) (OMA1) |
CNY 3,912.00 |
|
| SC323927 | OMA1 (untagged)-Human OMA1 homolog, zinc metallopeptidase (S. cerevisiae) (OMA1) |
CNY 3,912.00 |
