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IRAK2 (NM_001570) Human Tagged ORF Clone
CAT＃: RC218437
- TrueORF®
IRAK2 (Myc-DDK-tagged)-Human interleukin-1 receptor-associated kinase 2 (IRAK2)
ORF Plasmid: tGFP
"NM_001570" in other vectors (6)
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CNY 6,976.00
| Cited in 1 publication. |
Product images
CNY 300.00
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | IRAK-2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC218437 representing NM_001570
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCCTGCTACATCTACCAGCTGCCCTCCTGGGTGCTGGACGACCTGTGCCGCAACATGGACGCGCTCA GCGAGTGGGACTGGATGGAGTTCGCCTCCTACGTGATCACAGACCTGACCCAGCTGCGGAAGATCAAGTC CATGGAGCGGGTGCAGGGTGTGAGCATCACGCGGGAGCTGCTGTGGTGGTGGGGCATGCGGCAGGCCACC GTCCAGCAACTTGTGGACCTCCTGTGCCGCCTGGAGCTCTACCGGGCTGCCCAGATCATCCTGAACTGGA AACCGGCTCCTGAAATCAGGTGTCCCATTCCAGCCTTCCCTGACTCTGTGAAGCCAGAAAAGCCTTTGGC AGCTTCTGTAAGAAAGGCTGAGGATGAACAGGAAGAGGGGCAGCCTGTGAGGATGGCCACCTTTCCAGGC CCAGGGTCCTCTCCAGCCAGAGCCCACCAGCCGGCCTTTCTCCAGCCTCCTGAAGAAGATGCCCCTCATT CCTTGAGAAGCGACCTCCCCACTTCGTCTGATTCAAAGGACTTCAGCACCTCCATTCCTAAGCAGGAAAA ACTTTTGAGCTTGGCTGGAGACAGCCTTTTCTGGAGTGAGGCAGACGTGGTCCAGGCAACCGATGACTTC AATCAAAACCGCAAAATCAGCCAGGGGACCTTTGCTGACGTCTACAGAGGGCACAGGCACGGGAAGCCAT TCGTCTTCAAGAAGCTCAGAGAGACAGCCTGTTCAAGTCCAGGATCAATCGAAAGATTCTTCCAGGCAGA GTTGCAGATTTGTCTTAGATGCTGCCACCCCAATGTCTTACCTGTGCTGGGCTTCTGTGCTGCAAGACAG TTTCACAGCTTCATCTACCCCTACATGGCAAATGGTTCCCTACAGGACAGACTGCAGGGTCAGGGTGGCT CGGACCCCCTCCCCTGGCCCCAGCGTGTCAGCATCTGCTCAGGGCTGCTCTGTGCCGTCGAGTACCTGCA TGGTCTGGAGATCATCCACAGCAACGTCAAGAGCTCTAATGTCTTGCTGGACCAAAATCTCACCCCCAAA CTTGCTCACCCAATGGCTCATCTGTGTCCTGTCAACAAAAGGTCAAAATACACCATGATGAAGACTCACC TGCTCCGGACGTCAGCCGCGTATCTGCCAGAGGATTTCATCCGGGTGGGGCAGCTGACAAAGCGAGTGGA CATCTTCAGCTGTGGAATAGTGTTGGCCGAGGTCCTCACGGGCATCCCTGCAATGGATAACAACCGAAGC CCGGTTTACCTGAAGGACTTACTCCTCAGTGATATTCCAAGCAGCACCGCCTCGCTCTGCTCCAGGAAGA CGGGCGTGGAGAACGTGATGGCAAAGGAGATCTGCCAGAAGTACCTGGAGAAGGGCGCAGGGAGGCTTCC GGAGGACTGCGCCGAGGCCCTGGCCACGGCTGCCTGCCTGTGCCTGCGGAGGCGTAACACCAGCCTGCAG GAGGTGTGTGGCTCTGTGGCTGCTGTGGAAGAGCGGCTCCGAGGTCGGGAGACGTTGCTCCCTTGGAGTG GGCTTTCTGAGGGTACAGGCTCTTCTTCCAACACCCCAGAGGAAACAGACGACGTTGACAATTCCAGCCT TGATGCCTCCTCCTCCATGAGTGTGGCACCCTGGGCAGGGGCTGCCACCCCACTTCTCCCCACAGAGAAT GGGGAAGGAAGGCTGCGGGTCATCGTGGGAAGGGAGGCTGACTCCTCCTCTGAGGCCTGTGTTGGCCTGG AGCCTCCCCAGGATGTTACAGAAACTTCGTGGCAAATTGAGATCAATGAGGCCAAAAGGAAACTGATGGA GAATATTCTGCTCTACAAAGAGGAAAAAGTGGACAGCATTGAGCTCTTTGGCCCC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC218437 representing NM_001570
Red=Cloning site Green=Tags(s) MACYIYQLPSWVLDDLCRNMDALSEWDWMEFASYVITDLTQLRKIKSMERVQGVSITRELLWWWGMRQAT VQQLVDLLCRLELYRAAQIILNWKPAPEIRCPIPAFPDSVKPEKPLAASVRKAEDEQEEGQPVRMATFPG PGSSPARAHQPAFLQPPEEDAPHSLRSDLPTSSDSKDFSTSIPKQEKLLSLAGDSLFWSEADVVQATDDF NQNRKISQGTFADVYRGHRHGKPFVFKKLRETACSSPGSIERFFQAELQICLRCCHPNVLPVLGFCAARQ FHSFIYPYMANGSLQDRLQGQGGSDPLPWPQRVSICSGLLCAVEYLHGLEIIHSNVKSSNVLLDQNLTPK LAHPMAHLCPVNKRSKYTMMKTHLLRTSAAYLPEDFIRVGQLTKRVDIFSCGIVLAEVLTGIPAMDNNRS PVYLKDLLLSDIPSSTASLCSRKTGVENVMAKEICQKYLEKGAGRLPEDCAEALATAACLCLRRRNTSLQ EVCGSVAAVEERLRGRETLLPWSGLSEGTGSSSNTPEETDDVDNSSLDASSSMSVAPWAGAATPLLPTEN GEGRLRVIVGREADSSSEACVGLEPPQDVTETSWQIEINEAKRKLMENILLYKEEKVDSIELFGP TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001570 |
| ORF Size | 1875 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001570.4 |
| RefSeq Size | 3469 bp |
| RefSeq ORF | 1878 bp |
| Locus ID | 3656 |
| UniProt ID | O43187 |
| Domains | DEATH, pkinase |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Apoptosis, Neurotrophin signaling pathway |
| MW | 69.3 kDa |
| Gene Summary | IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
IRAK2 counterbalances oncogenic Smurf1 in colon cancer cells by dictating ER stress.
,null,
Cellular signalling
,PubMed ID 29753111
[IRAK2]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218437L1 | Lenti-ORF clone of IRAK2 (Myc-DDK-tagged)-Human interleukin-1 receptor-associated kinase 2 (IRAK2) |
CNY 9,376.00 |
|
| RC218437L2 | Lenti-ORF clone of IRAK2 (mGFP-tagged)-Human interleukin-1 receptor-associated kinase 2 (IRAK2) |
CNY 9,376.00 |
|
| RC218437L3 | Lenti-ORF clone of IRAK2 (Myc-DDK-tagged)-Human interleukin-1 receptor-associated kinase 2 (IRAK2) |
CNY 5,890.00 |
|
| RC218437L4 | Lenti-ORF clone of IRAK2 (mGFP-tagged)-Human interleukin-1 receptor-associated kinase 2 (IRAK2) |
CNY 9,376.00 |
|
| RG218437 | IRAK2 (tGFP-tagged) - Human interleukin-1 receptor-associated kinase 2 (IRAK2) |
CNY 4,370.00 |
|
| SC310211 | IRAK2 (untagged)-Human interleukin-1 receptor-associated kinase 2 (IRAK2) |
CNY 6,992.00 |
