OATP2 (SLCO1B1) (NM_006446) Human Tagged ORF Clone

CAT＃: RC222130

  • TrueORF®

SLCO1B1 (Myc-DDK-tagged)-Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1)

ORF Plasmid: DDK tGFP

Datasheet
SDS
Plasmid Map

  "NM_006446" in other vectors (6)

Need custom modification / cloning service?
Get a free quote

CNY 3,990.00

货期*
现货
规格
    • 10 ug
Cited in 3 publications.

Product images

经常一起买 (5)
PS100001
pCMV6-Entry, mammalian vector with C-terminal Myc- DDK Tag, 10ug
    • 10 ug

CNY 5,420.00

添加到购物车
CC100003
DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

暂停销售
PRIMER
Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

添加到购物车
TA592569S
DDK Rabbit monoclonal antibody, recognizing both N- and C-terminal tags
    • 30 ul

CNY 300.00

添加到购物车

【特别福利】购一抗正装产品，免费领10ul抗体试用装

TA315080
Rabbit polyclonal anti-SLCO1B1 antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

添加到购物车

Specifications

Product Data
Type Human Tagged ORF Clone
Tag Myc-DDK
Synonyms HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2; OATPC; SLC21A6
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>RC222130 representing NM_006446
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGACCAAAATCAACATTTGAATAAAACAGCAGAGGCACAACCTTCAGAGAATAAGAAAACAAGATACT
GCAATGGATTGAAGATGTTCTTGGCAGCTCTGTCACTCAGCTTTATTGCTAAGACACTAGGTGCAATTAT
TATGAAAAGTTCCATCATTCATATAGAACGGAGATTTGAGATATCCTCTTCTCTTGTTGGTTTTATTGAC
GGAAGCTTTGAAATTGGAAATTTGCTTGTGATTGTATTTGTGAGTTACTTTGGATCCAAACTACATAGAC
CAAAGTTAATTGGAATCGGTTGTTTCATTATGGGAATTGGAGGTGTTTTGACTGCTTTGCCACATTTCTT
CATGGGATATTACAGGTATTCTAAAGAAACTAATATCGATTCATCAGAAAATTCAACATCGACCTTATCC
ACTTGTTTAATTAATCAAATTTTATCACTCAATAGAGCATCACCTGAGATAGTGGGAAAAGGTTGTTTAA
AGGAATCTGGGTCATACATGTGGATATATGTGTTCATGGGTAATATGCTTCGTGGAATAGGGGAGACTCC
CATAGTACCATTGGGGCTTTCTTACATTGATGATTTCGCTAAAGAAGGACATTCTTCTTTGTATTTAGGT
ATATTGAATGCAATAGCAATGATTGGTCCAATCATTGGCTTTACCCTGGGATCTCTGTTTTCTAAAATGT
ACGTGGATATTGGATATGTAGATCTAAGCACTATCAGGATAACTCCTACTGATTCTCGATGGGTTGGAGC
TTGGTGGCTTAATTTCCTTGTGTCTGGACTATTCTCCATTATTTCTTCCATACCATTCTTTTTCTTGCCC
CAAACTCCAAATAAACCACAAAAAGAAAGAAAAGCTTCACTGTCTTTGCATGTGCTGGAAACAAATGATG
AAAAGGATCAAACAGCTAATTTGACCAATCAAGGAAAAAATATTACCAAAAATGTGACTGGTTTTTTCCA
GTCTTTTAAAAGCATCCTTACTAATCCCCTGTATGTTATGTTTGTGCTTTTGACGTTGTTACAAGTAAGC
AGCTATATTGGTGCTTTTACTTATGTCTTCAAATACGTAGAGCAACAGTATGGTCAGCCTTCATCTAAGG
CTAACATCTTATTGGGAGTCATAACCATACCTATTTTTGCAAGTGGAATGTTTTTAGGAGGATATATCAT
TAAAAAATTCAAACTGAACACCGTTGGAATTGCCAAATTCTCATGTTTTACTGCTGTGATGTCATTGTCC
TTTTACCTATTATATTTTTTCATACTCTGTGAAAACAAATCAGTTGCCGGACTAACCATGACCTATGATG
GAAATAATCCAGTGACATCTCATAGAGATGTACCACTTTCTTATTGCAACTCAGACTGCAATTGTGATGA
AAGTCAATGGGAACCAGTCTGTGGAAACAATGGAATAACTTACATCTCACCCTGTCTAGCAGGTTGCAAA
TCTTCAAGTGGCAATAAAAAGCCTATAGTGTTTTACAACTGCAGTTGTTTGGAAGTAACTGGTCTCCAGA
ACAGAAATTACTCAGCCCATTTGGGTGAATGCCCAAGAGATGATGCTTGTACAAGGAAATTTTACTTTTT
TGTTGCAATACAAGTCTTGAATTTATTTTTCTCTGCACTTGGAGGCACCTCACATGTCATGCTGATTGTT
AAAATTGTTCAACCTGAATTGAAATCACTTGCACTGGGTTTCCACTCAATGGTTATACGAGCACTAGGAG
GAATTCTAGCTCCAATATATTTTGGGGCTCTGATTGATACAACGTGTATAAAGTGGTCCACCAACAACTG
TGGCACACGTGGGTCATGTAGGACATATAATTCCACATCATTTTCAAGGGTCTACTTGGGCTTGTCTTCA
ATGTTAAGAGTCTCATCACTTGTTTTATATATTATATTAATTTATGCCATGAAGAAAAAATATCAAGAGA
AAGATATCAATGCATCAGAAAATGGAAGTGTCATGGATGAAGCAAACTTAGAATCCTTAAATAAAAATAA
ACATTTTGTCCCTTCTGCTGGGGCAGATAGTGAAACACATTGT

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
>RC222130 representing NM_006446
Red=Cloning site Green=Tags(s)

MDQNQHLNKTAEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFID
GSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNIDSSENSTSTLS
TCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLG
ILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLP
QTPNKPQKERKASLSLHVLETNDEKDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVS
SYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLS
FYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCK
SSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTSHVMLIV
KIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYLGLSS
MLRVSSLVLYIILIYAMKKKYQEKDINASENGSVMDEANLESLNKNKHFVPSAGADSETHC

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Chromatograms CHROMATOGRAMS
Sequencher program is needed, download here.
Restriction Sites SgfI-MluI      Cloning Scheme for this gene      Plasmid Map     
ACCN NM_006446
ORF Size 2073 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_006446.3
RefSeq Size 2830 bp
RefSeq ORF 2076 bp
Locus ID 10599
UniProt ID Q9Y6L6
Domains OATP_N, OATP_C
Protein Families Druggable Genome, Transmembrane
MW 76.3 kDa
Gene Summary This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (3)

The use of this cDNA Clones has been cited in the following citations:
Characterization of Plasma Membrane Localization and Phosphorylation Status of Organic Anion Transporting Polypeptide (OATP) 1B1 c.521 T>C Nonsynonymous Single-Nucleotide Polymorphism ,Crowe, A;Zheng, W;Miller, J;Pahwa, S;Alam, K;Fung, KM;Rubin, E;Yin, F;Ding, K;Yue, W;, Pharm. Res. ,PubMed ID 31093828 [OATP2]
A phosphotyrosine switch regulates organic cation transporters ,Sprowl, JA;Ong, SS;Gibson, AA;Hu, S;Du, G;Lin, W;Li, L;Bharill, S;Ness, RA;Stecula, A;Offer, SM;Diasio, RB;Nies, AT;Schwab, M;Cavaletti, G;Schlatter, E;Ciarimboli, G;Schellens, JH;Isacoff, EY;Sali, A;Chen, T;Baker, SD;Sparreboom, A;Pabla, N;, Nat Commun ,PubMed ID 26979622 [OATP2]
Down-Regulation of Organic Anion Transporting Polypeptide (OATP) 1B1 Transport Function by Lysosomotropic Drug Chloroquine ,Alam, K;Pahwa, S;Wang, X;Zhang, P;Ding, K;, Molecular pharmarceutics ,PubMed ID 26750564 [OATP2]

Other Versions

SKU Description Size Price
RC222130L1 Lenti ORF clone of Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1), Myc-DDK-tagged
    • 10 ug

CNY 5,890.00

RC222130L2 Lenti ORF clone of Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1), mGFP tagged
    • 10 ug

CNY 5,890.00

RC222130L3 Lenti ORF clone of Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1), Myc-DDK-tagged
    • 10 ug

CNY 5,890.00

RC222130L4 Lenti ORF clone of Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1), mGFP tagged
    • 10 ug

CNY 5,890.00

RG222130 SLCO1B1 (tGFP-tagged) - Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1)
    • 10 ug

CNY 4,370.00

SC116071 SLCO1B1 (untagged)-Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1)
    • 10 ug

CNY 7,600.00

You may also need
plasmid icon Empty Vector
protein iconDDK/Flag Antibody

其它OATP2产品

Expression Plasmids
Lentiviral Particles
CRISPR
RNAi
Proteins
Antibodies
相关产品 (13)

PS100001

pCMV6-Entry, mammalian vector with C-terminal Myc- DDK Tag, 10ug

    • 10 ug

CNY 5,420.00

TF81001

TurboFectin Transfection Reagent (1 mL in 1 vial)

    • 1 ml in 1 vial

CNY 4,090.00

TA50011-100

Clone OTI4C5, Anti-DDK (FLAG) monoclonal antibody

【特别福利】购一抗正装产品，免费领10ul抗体试用装

    • 100 ul

CNY 1,050.00

RC222130L2V

Lenti ORF particles, SLCO1B1 (mGFP-tagged) - Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1), 200ul, >10^7 TU/mL

    • 200 ul

CNY 9,975.00 暂停销售

RC222130L4V

Lenti ORF particles, SLCO1B1 (mGFP-tagged) - Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1), 200ul, >10^7 TU/mL

    • 200 ul

CNY 9,975.00 暂停销售

RC222130L1

Lenti ORF clone of Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1), Myc-DDK-tagged

    • 10 ug

CNY 5,890.00

RC222130L3

Lenti ORF clone of Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1), Myc-DDK-tagged

    • 10 ug

CNY 5,890.00

RC222130L3V

Lenti ORF particles, SLCO1B1 (Myc-DDK tagged) - Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1), 200ul, >10^7 TU/mL

    • 200 ul

CNY 8,930.00 暂停销售

RC222130L2

Lenti ORF clone of Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1), mGFP tagged

    • 10 ug

CNY 5,890.00

RG222130

SLCO1B1 (tGFP-tagged) - Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1)

    • 10 ug

CNY 4,370.00

RC222130L1V

Lenti ORF particles, SLCO1B1 (Myc-DDK tagged) - Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1), 200ul, >10^7 TU/mL

    • 200 ul

CNY 8,930.00 暂停销售

SC116071

SLCO1B1 (untagged)-Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1)

    • 10 ug

CNY 7,600.00

RC222130L4

Lenti ORF clone of Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1), mGFP tagged

    • 10 ug

CNY 5,890.00

Previous
Next
Customer Reviews