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ADAMTS8 (NM_007037) Human Tagged ORF Clone
CAT＃: RG212446
- TrueORF®
ADAMTS8 (tGFP-tagged) - Human ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ADAMTS8)
ORF Plasmid: DDK
"NM_007037" in other vectors (4)
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CNY 8,104.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | ADAM-TS8; METH2 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG212446 representing NM_007037
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCTCCCCGCCCCCGCCGCCCCCCGGTGGCCTCCGCTCCTGCTGCTGCTGCTGCTGCTGCTGCCGCTGG CCCGCGGCGCCCCGGCCCGGCCCGCAGCCGGGGGGCAGGCCTCGGAGCTGGTGGTGCCCACGCGGTTGCC CGGCAGCGCGGGCGAGCTCGCGCTCCACCTGTCCGCCTTCGGCAAGGGCTTCGTGCTGCGCCTGGCGCCC GACGACAGCTTCCTAGCGCCCGAGTTCAAGATCGAGCGCCTCGGGGGCTCCGGCCGGGCGACCGGGGGCG AGCGGGGGCTGCGCGGCTGCTTCTTCTCCGGCACCGTGAATGGGGAGCCCGAGTCGCTGGCGGCGGTCAG CCTGTGCCGCGGGCTGAGCGGCTCCTTCCTGCTGGACGGCGAGGAGTTCACCATCCAGCCGCAGGGCGCG GGGGGCTCCCTGGCTCAGCCGCACCGCCTGCAGCGCTGGGGTCCCGCCGGAGCCCGCCCCCTCCCGCGAG GACCCGAGTGGGAGGTGGAGACGGGAGAGGGTCAGAGGCAGGAGAGAGGAGACCACCAGGAGGACAGCGA GGAGGAGAGCCAAGAAGAGGAGGCAGAAGGCGCTAGCGAGCCGCCACCGCCCCTGGGGGCCACGAGTAGG ACCAAGCGGTTTGTGTCTGAGGCGCGCTTCGTGGAGACGCTGCTGGTGGCCGATGCGTCCATGGCTGCCT TCTACGGGGCCGACCTGCAGAACCACATCCTGACGTTAATGTCTGTGGCAGCCCGAATCTACAAGCACCC CAGCATCAAGAATTCCATCAACCTGATGGTGGTAAAAGTGCTGATCGTAGAAGATGAAAAATGGGGCCCA GAGGTGTCCGACAATGGGGGGCTTACACTGCGTAACTTCTGCAACTGGCAGCGGCGTTTCAACCAGCCCA GCGACCGCCACCCAGAGCACTACGACACGGCCATCCTGCTCACCAGACAGAACTTCTGTGGGCAGGAGGG GCTGTGTGACACCCTGGGTGTGGCAGACATCGGGACCATTTGTGACCCCAACAAAAGCTGCTCCGTGATC GAGGATGAGGGGCTCCAGGCGGCCCACACCCTGGCCCATGAACTAGGGCACGTCCTCAGCATGCCCCACG ACGACTCCAAGCCCTGCACACGGCTCTTCGGGCCCATGGGCAAGCACCACGTGATGGCACCGCTGTTCGT CCACCTGAACCAGACGCTGCCCTGGTCCCCCTGCAGCGCCATGTATCTCACAGAGCTTCTGGACGGCGGG CACGGAGACTGTCTCCTGGATGCCCCTGGTGCGGCCCTGCCCCTCCCCACAGGCCTCCCGGGCCGCATGG CCCTGTACCAGCTGGACCAGCAGTGCAGGCAGATCTTTGGGCCGGATTTCCGCCACTGCCCCAACACCTC TGCTCAGGACGTCTGCGCCCAGCTTTGGTGCCACACTGATGGGGCTGAGCCCCTGTGCCACACGAAGAAT GGCAGCCTGCCCTGGGCTGACGGCACGCCGTGCGGGCCTGGGCACCTCTGCTCAGAAGGCAGCTGTCTAC CTGAGGAGGAAGTGGAGAGGCCCAAGCCCGTGGTAGATGGAGGCTGGGCACCGTGGGGACCCTGGGGAGA ATGTTCTCGGACCTGTGGAGGAGGAGTACAGTTTTCACACCGTGAGTGCAAGGACCCCGAGCCTCAGAAT GGAGGAAGATACTGCCTGGGTCGGAGAGCCAAGTACCAGTCATGCCACACGGAGGAATGCCCCCCTGACG GGAAAAGCTTCAGGGAGCAGCAGTGTGAGAAGTATAATGCCTACAATTACACTGACATGGACGGGAATCT CCTGCAGTGGGTCCCCAAGTATGCTGGGGTGTCCCCCCGGGACCGCTGCAAGTTGTTCTGCCGAGCCCGG GGGAGGAGCGAGTTCAAAGTGTTCGAGGCCAAGGTGATTGATGGCACCCTGTGTGGGCCAGAAACACTGG CCATCTGTGTCCGTGGCCAGTGTGTCAAGGCCGGCTGTGACCATGTGGTGGACTCGCCTCGGAAGCTGGA CAAATGCGGGGTGTGTGGGGGCAAAGGCAACTCCTGCAGGAAGGTCTCCGGGTCCCTCACCCCCACCAAT TATGGCTACAATGACATTGTCACCATCCCAGCTGGTGCCACTAATATTGACGTGAAGCAGCGGAGCCACC CGGGTGTGCAGAACGATGGGAACTACCTGGCGCTGAAGACGGCTGATGGGCAGTACCTGCTCAACGGCAA CCTGGCCATCTCTGCCATAGAGCAGGACATCTTGGTGAAGGGGACCATCCTGAAGTACAGCGGCTCCATC GCCACCCTGGAGCGCCTGCAGAGCTTCCGGCCCTTGCCAGAGCCTCTGACAGTGCAGCTCCTGACAGTCC CTGGCGAGGTCTTCCCCCCAAAAGTCAAATACACCTTCTTTGTTCCTAATGACGTGGACTTTAGCATGCA GAGCAGCAAAGAGAGAGCAACCACCAACATCATCCAGCCGCTGCTCCACGCACAGTGGGTGCTGGGGGAC TGGTCTGAGTGCTCTAGCACCTGCGGGGCCGGCTGGCAGAGGCGAACTGTAGAGTGCAGGGACCCCTCCG GCCAGGCCTCTGCCACCTGCAACAAGGCTCTGAAACCCGAGGATGCCAAGCCCTGCGAAAGCCAGCTGTG CCCCCTG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG212446 representing NM_007037
Red=Cloning site Green=Tags(s) MLPAPAAPRWPPLLLLLLLLLPLARGAPARPAAGGQASELVVPTRLPGSAGELALHLSAFGKGFVLRLAP DDSFLAPEFKIERLGGSGRATGGERGLRGCFFSGTVNGEPESLAAVSLCRGLSGSFLLDGEEFTIQPQGA GGSLAQPHRLQRWGPAGARPLPRGPEWEVETGEGQRQERGDHQEDSEEESQEEEAEGASEPPPPLGATSR TKRFVSEARFVETLLVADASMAAFYGADLQNHILTLMSVAARIYKHPSIKNSINLMVVKVLIVEDEKWGP EVSDNGGLTLRNFCNWQRRFNQPSDRHPEHYDTAILLTRQNFCGQEGLCDTLGVADIGTICDPNKSCSVI EDEGLQAAHTLAHELGHVLSMPHDDSKPCTRLFGPMGKHHVMAPLFVHLNQTLPWSPCSAMYLTELLDGG HGDCLLDAPGAALPLPTGLPGRMALYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLWCHTDGAEPLCHTKN GSLPWADGTPCGPGHLCSEGSCLPEEEVERPKPVVDGGWAPWGPWGECSRTCGGGVQFSHRECKDPEPQN GGRYCLGRRAKYQSCHTEECPPDGKSFREQQCEKYNAYNYTDMDGNLLQWVPKYAGVSPRDRCKLFCRAR GRSEFKVFEAKVIDGTLCGPETLAICVRGQCVKAGCDHVVDSPRKLDKCGVCGGKGNSCRKVSGSLTPTN YGYNDIVTIPAGATNIDVKQRSHPGVQNDGNYLALKTADGQYLLNGNLAISAIEQDILVKGTILKYSGSI ATLERLQSFRPLPEPLTVQLLTVPGEVFPPKVKYTFFVPNDVDFSMQSSKERATTNIIQPLLHAQWVLGD WSECSSTCGAGWQRRTVECRDPSGQASATCNKALKPEDAKPCESQLCPL TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_007037 |
| ORF Size | 2667 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_007037.3, NP_008968.3 |
| RefSeq Size | 4028 bp |
| RefSeq ORF | 2670 bp |
| Locus ID | 11095 |
| UniProt ID | Q9UP79 |
| Protein Families | Druggable Genome, Protease, Secreted Protein |
| Gene Summary | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. Reduced expression of this gene has been observed in multiple human cancers and this gene has been proposed as a potential tumor suppressor. [provided by RefSeq, Feb 2016] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212446 | ADAMTS8 (Myc-DDK-tagged)-Human ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ADAMTS8) |
CNY 6,504.00 |
|
| RC212446L3 | Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ADAMTS8), Myc-DDK-tagged |
CNY 11,310.00 |
|
| RC212446L4 | Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ADAMTS8), mGFP tagged |
CNY 8,904.00 |
|
| SC123949 | ADAMTS8 (untagged)-Human ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ADAMTS8) |
CNY 6,520.00 |
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