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FRS2 (NM_001278353) Human Tagged ORF Clone
CAT＃: RG238620
- TrueORF®
FRS2 (tGFP-tagged) - Human fibroblast growth factor receptor substrate 2 (FRS2), transcript variant 4
ORF Plasmid: DDK
"NM_001278353" in other vectors (2)
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CNY 4,750.00
Product images
Specifications
| Product Data | |
| Tag | TurboGFP |
| Synonyms | FRS1A; FRS2A; FRS2alpha; SNT; SNT-1; SNT1 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG238620 representing NM_001278353.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTC ATTAATGTGGATGATGATGGGAATGAGTTAGGTTCTGGCATAATGGAACTTACAGACACAGAACTGATT TTATACACCCGCAAACGTGACTCAGTAAAATGGCACTACCTCTGCCTGCGACGCTATGGCTATGACTCG AATCTCTTTTCTTTTGAAAGTGGTCGAAGGTGTCAAACTGGACAAGGAATCTTTGCCTTTAAGTGTGCC CGTGCAGAAGAATTATTTAACATGTTGCAAGAGATTATGCAAAATAATAGTATAAATGTGGTGGAAGAG CCAGTTGTAGAAAGAAATAATCATCAGACAGAATTGGAAGTCCCTAGAACACCTCGAACACCTACAACT CCAGGATTTGCTGCTCAGAACTTACCTAATGGATATCCCCGATATCCCTCATTTGGAGATGCTTCATCC CATCCGTCAAGCAGACATCCTTCTGTGGGAAGTGCTCGCCTGCCTTCAGTAGGGGAAGAATCTACACAT CCTTTGCTTGTGGCTGAGGAACAAGTACATACCTATGTCAACACTACAGGTGTGCAAGAAGAGCGGAAA AACCGCACAAGTGTGCATGTTCCATTGGAGGCAAGGGTTTCTAACGCTGAAAGCAGCACACCAAAAGAA GAACCAAGTAGTATTGAGGACAGGGATCCTCAGATTCTTCTTGAACCTGAAGGAGTCAAATTTGTTTTA GGGCCAACCCCTGTTCAAAAGCAGTTAATGGAAAAAGAGAAACTGGAGCAACTTGGAAGAGATCAAGTT AGTGGAAGTGGAGCAAATAACACAGAATGGGACACTGGCTATGACAGTGATGAACGAAGAGATGCACCC TCTGTTAACAAACTGGTGTATGAAAATATAAATGGGCTATCTATCCCTAGTGCCTCAGGGGTCAGGAGA GGTCGTCTGACATCCACCAGTACCTCAGATACCCAGAATATCAACAACTCAGCTCAGAGAAGAACTGCA TTATTAAACTATGAAAATCTACCATCTTTGCCTCCTGTTTGGGAAGCCCGCAAGCTAAGTAGGGATGAA GATGACAATTTAGGACCAAAGACCCCATCTCTAAATGGCTACCATAATAATCTAGATCCAATGCATAAC TATGTAAATACAGAGAATGTAACAGTGCCAGCAAGTGCTCACAAAATAGAATATTCAAGGCGTCGGGAC TGTACACCAACAGTCTTTAACTTTGATATCAGACGCCCAAGTTTAGAACACAGGCAGCTTAATTACATA CAGGTTGACTTGGAAGGTGGCAGTGACTCTGACAACCCTCAGACTCCAAAAACGCCTACAACTCCCCTT CCACAAACCCCTACCAGGCGCACAGAGCTGTATGCCGTGATAGACATCGAGAGAACTGCTGCTATGTCA AATTTGCAGAAAGCACTGCCACGAGATGATGGTACATCTAGGAAAACTAGACACAATAGTACTGATCTG CCCATGTTAGCCTGGAAA ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG238620
Blue=ORF Red=Cloning site Green=Tag(s) MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYLCLRRYGYDS NLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVERNNHQTELEVPRTPRTPTT PGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQEERK NRTSVHVPLEARVSNAESSTPKEEPSSIEDRDPQILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQV SGSGANNTEWDTGYDSDERRDAPSVNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRTA LLNYENLPSLPPVWEARKLSRDEDDNLGPKTPSLNGYHNNLDPMHNYVNTENVTVPASAHKIEYSRRRD CTPTVFNFDIRRPSLEHRQLNYIQVDLEGGSDSDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTAAMS NLQKALPRDDGTSRKTRHNSTDLPMLAWK TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001278353 |
| ORF Size | 1536 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001278353.1, NP_001265282.1 |
| RefSeq Size | 6940 bp |
| RefSeq ORF | 1527 bp |
| Locus ID | 10818 |
| UniProt ID | Q8WU20 |
| Protein Families | Druggable Genome |
| Protein Pathways | Neurotrophin signaling pathway |
| MW | 57.5 kDa |
| Gene Summary | Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
