ALKBH7 (NM_032306) Human Untagged Clone
CAT＃: SC105069
ALKBH7 (untagged)-Human alkB, alkylation repair homolog 7 (E. coli) (ALKBH7)
CNY 2400.00
CNY 2950.00
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Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ABH7; SPATA11; UNQ6002 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC105069 sequence for NM_032306 edited (data generated by NextGen Sequencing)
ATGGCCGGGACTGGGCTGCTGGCGCTGCGGACGCTGCCAGGGCCCAGCTGGGTGCGAGGC TCGGGCCCTTCCGTGCTGAGCCGCCTGCAGGACGCGGCCGTGGTGCGGCCTGGCTTCCTG AGCACGGCAGAGGAGGAGACGCTGAGCCGAGAACTGGAGCCCGAGCTGCGCCGCCGCCGC TACGAATACGATCACTGGGACGCGGCCATCCACGGCTTCCGAGAGACAGAGAAGTCGCGC TGGTCAGAAGCCAGCCGGGCCATCCTGCAGCGCGTGCAGGCGGCCGCCTTTGGCCCCGGC CAGACCCTGCTCTCCTCCGTGCACGTGCTGGACCTGGAAGCCCGCGGCTACATCAAGCCC CACGTGGACAGCATCAAGTTCTGCGGGGCCACCATCGCCGGCCTGTCTCTCCTGTCTCCC AGCGTTATGCGGCTGGTGCACACCCAGGAGCCGGGGGAGTGGCTGGAACTCTTGCTGGAG CCGGGCTCCCTCTACATCCTTAGGGGCTCAGCCCGTTATGACTTCTCCCATGAGATCCTT CGGGATGAAGAGTCCTTCTTTGGGGAACGCCAGATTCCCCGGGGCCGGCGCATCTCCGTG ATCTGCCGCTCCCTCCCTGAGGGCATGGGGCCAGGGGAGTCTGGACAGCCGCCCCCAGCC TGCTGA Clone variation with respect to NM_032306.3 572 g=>a >OriGene 5' read for NM_032306 unedited
CACGAGGGGATTATGGCCGGGACTGGGCTGCTGGCGCTGCGGACGCTGCCAGGGCCCAGC TGGGTGCGAGGCTCGGGCCCTTCCGTGCTGAGCCGCCTGCAGGACGCGGCCGTGGTGCGG CCTGGCTTCCTGAGCACGGCAGAGGAGGAGACGCTGAGCCGAGAACTGGAGCCCGAGCTG CGCCGCCGCCGCTACGAATACGATCACTGGGACGCGGCCATCCACGGCTTCCGAGAGACA GAGAAGTCGCGCTGGTCAGAAGCCAGCCGGGCCATCCTGCAGCGCGTGCAGGCGGCCGCC TTTGGCCCCGGCCAGACCCTGCTCTCCTCCGTGCACGTGCTGGACCTGGAAGCCCGCGGC TACATCAAGCCCCACGTGGACAGCATCAAGTTCTGCGGGGCCACCATCGCCGGCCTGTCT CTCCTGTCTCCCAGCGTTATGCGGCTGGTGCACACCCAGGAGCCGGGGGAGTGGCTGGAA CTCTTGCTGGAGCCGGGCTCCCTCTACATCCTTAGGGGCTCAGCCCGTTATGACTTCTCC CATGAGATCCTTCGGGATGAAGAGTCCTTCTTTGGGGAACGCCAGATTCCCCGGGGCCGG CGCATCTCCGTGATCTGCCGCTCCCTCCCCTGAGGCATGGGGCCAGGGGAGTCTGGACAG CCGCCCCCAGCCTGCTGACCCCCAGCTTT >OriGene 3' read for NM_032306 unedited
TATGAACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTAGGCTGTCCATTCCCCAACTTTATTCACAAATCTGGTGTCTGTAAAAAGC TGGGGGTCAACAGGCTGGGGGCGGCTGTCCAAACTCCCCTGGCCCCATGCCCTCAGGGAG GGAGCGGCAGATCACGGAGATGCCCCGGCCCCGGGGAATCTGGCGTTCCCCAAAGAAGGA CTCTTCATCCCGAAGGATCTCATGGGAAAAGTCATAACGGGCTGAGCCCCTAAGGATGTA AAGGGAGCCCGGCTCCAGCAAGAGTTCCAGCCACTCCCCCGGCTCCTGGGTGTGCACCAG CCGCATAACGCTGGGAGACAGGAAAAACAGGCCGGCGATGGTGGCCCCGCAAAACTTGAT GCTGTCCACGTGGGGCTTGATGTAACCGCGGGCTTCCAGGTCCAGCACGTGCACGGAGGA AAGCAAGGTCTGGCCGGGGCCAAAGGCGGCCGCCTGCACGCGCTGCAAGATGGCCCGGCT GGCTTCTGACCAGCGCGACTTCTCTGTCTCTCGGAAGCCGTGGATGGCCGCGTCCCAGTG ATCGTATTCGTAGCGGCGGCGGCGCAGCTCGGGCTCCAGTTCTCGGCTCAACGTCTCCTC CTCTGGCGTGCTCAGGAAGCCAGGCCGCACCACGGCCGCGTCCTGGAAGCGGGTCAGCAC GGGAGGGCCCGAAGCTCGCACCCAGCTGGGCCCTGGGAGCGTCCGCAACGCCAGCAACCC AATCCCGCCATAATTCCCTCGTGCCCAATTCGCGGCCGCCCTATAGGGAGTCGATTACAA AAATCTGACGGTTCACTAAAGAGGCCTGCTTAATAGACTCCCACCGAACGCCTCACGCCA TTTGGGTAACGGGGCGGGGTATTCCAACTTTGAAAGCCCGTGATTTGGGGCCCAACAACC CCTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_032306 |
| Insert Size | 800 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_032306.2, NP_115682.1 |
| RefSeq Size | 1110 bp |
| RefSeq ORF | 666 bp |
| Locus ID | 84266 |
| UniProt ID | Q9BT30 |
| Gene Summary | May function as protein hydroxylase; can catalyze auto-hydroxylation at Leu-110 (in vitro), but this activity may be due to the absence of the true substrate (PubMed:25122757). Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death (PubMed:23666923). ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage (PubMed:23666923). Does not display DNA demethylase activity (PubMed:23666923). Involved in fatty acid metabolism (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202583 | ALKBH7 (Myc-DDK-tagged)-Human alkB, alkylation repair homolog 7 (E. coli) (ALKBH7) |
CNY 2400.00 |
|
| RC202583L1 | Lenti ORF clone of Human alkB, alkylation repair homolog 7 (E. coli) (ALKBH7), Myc-DDK-tagged |
CNY 4800.00 |
|
| RC202583L2 | Lenti ORF clone of Human alkB, alkylation repair homolog 7 (E. coli) (ALKBH7), mGFP tagged |
CNY 5890.00 |
|
| RC202583L3 | Lenti ORF clone of Human alkB, alkylation repair homolog 7 (E. coli) (ALKBH7), Myc-DDK-tagged |
CNY 5890.00 |
|
| RC202583L4 | Lenti ORF clone of Human alkB, alkylation repair homolog 7 (E. coli) (ALKBH7), mGFP tagged |
CNY 5890.00 |
|
| RG202583 | ALKBH7 (tGFP-tagged) - Human alkB, alkylation repair homolog 7 (E. coli) (ALKBH7) |
CNY 4000.00 |
