IFI27 (NM_005532) Human Untagged Clone
CAT＃: SC116713
IFI27 (untagged)-Human interferon, alpha-inducible protein 27 (IFI27), transcript variant 2
CNY 1200.00
CNY 3990.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FAM14D; ISG12; ISG12A; P27 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC116713 sequence for NM_005532 edited (data generated by NextGen Sequencing)
ATGGAGGCCTCTGCTCTCACCTCATCAGCAGTGACCAGTGTGGCCAAAGTGGTCAGGGTG GCCTCTGGCTCTGCCGTAGTTTTGCCCCTGGCCAGGATTGCTACAGTTGTGATTGGAGGA GTTGTGGCTGTGCCCATGGTGCTCAGTGCCATGGGCTTCACTGCGGCGGGAATCGCCTCG TCCTCCATAGCAGCCAAGATGATGTCCGCGGCGGCCATTGCCAATGGGGGTGGAGTTGCC TCGGGCAGCCTTGTGGCTACTCTGCAGTCACTGGGAGCAACTGGACTCTCCGGATTGACC AAGTTCATCCTGGGCTCCATTGGGTCTGCCATTGCGGCTGTCATTGCGAGGTTCTACTAG Clone variation with respect to NM_005532.3 >OriGene 5' read for NM_005532 unedited
NNCAGGTTCGGATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGGTGA GGTCAGCTTCACATTCTCAGGAACTCTCCTTCTTTGGGTCTGGCTGAAGTTGAGGATCTC TTACTCTCTAGGCCACGGAATTAACCCGAGCAGGCATGGAGGCCTCTGCTCTCACCTCAT CAGCAGTGACCAGTGTGGCCAAAGTGGTCAGGGTGGCCTCTGGCTCTGCCGTAGTTTTGC CCCTGGCCAGGATTGCTACAGTTGTGATTGGAGGAGTTGTGGCTGTGCCCATGGTGCTCA GTGCCATGGGCTTCACTGCGGCGGGAATCGCCTCGTCCTCCATAGCAGCCAAGATGATGT CCGCGGCGGCCATTGCCAATGGGGGTGGAGTTGCCTCGGGCAGCCTTGTGGCTACTCTGC AGTCACTGGGAGCAACTGGACTCTCCGGATTGACCAAGTTCATCCTGGGCTCCATTGGGT CTGCCATTGCGGCTGTCATTGCGAGGTTCTACTAGCTCCCTGCCCCTCGCCCTGCAGAGA AGAGAACCATGCCAGGGGAGAAGGCACCCAGCCATCCTGACCCAGCGAGGAGCCAACTAT CCCAAATATACCTGGGGTGAAATATACCAAATTCTGCATCTCCAGAGGAAAATAAGAAAT AAAGATGAATTGTTGCAACTCANAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCG CGGTCATAGCTGTTTCCCTGACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGC CTCNTCTGGCCCTGGAAGTGCCACTCCAGTGCCCACCAGCCTTGGTCCTATAAAATTAAA GTGCATCATTTTGTCTGACTAGGTGTCCTTCTTAAATATGGTGAGGGGGGGGGTTTTTTT AATATAAG >OriGene 3' read for NM_005532 unedited
CCGCAATCTAGTATCGAGTTTTTTTTTTTTTTTTTTGAGTTGCAACAATTCATCTTTATT TCTTATTTTCCTCTGGAGATGCAGAATTTGGTATATTTCACCCCAGGTATATTTGGGATA GTTGGCTCCTCGCTGGGTCAAGATGGCTGGGTGCCTTCTCCCCTGGCATGGTTCTCTTCT CTGCAGGGCGAGGGGCAGGGAGCTATTATAACCTCGCAATGACAGCCGCAATGGCAGACC CAATGGAGCCCAGGATGAACTTGGTCAATCCGGAGAGTCCAGTTGCTCCCAGTGACTGCA GAGTATCCACAAGGCTGCCCGAGGCAACTCCACCCCCATTGGCAATGGCCGCCGCGGACA TCATCTTGGCTGCTATGGAGGACGAGGCGATTCCCGCCGCAGTGAAGCCCATGGCACTGA GCACCATGGGCACAGCCACAACTCCTCCAATCACAACTGTAGCAATCCTGGCCAGGGGCA AAACTACGGCAGAGCCAGAGGCCACCCTGACCACTTTGGCCACACTGGTCACTGCTGATG AAGTGAGAGCAAAAGCCTCCATGCCTGCTCGGGTTAATTCCGTGGCCTANAGAGTAAGAG ATCCTCAACTTCAGCCAGACCCAAAAGAAGGAGAGTTCCTGAGAATGTGAAGCTGACCTC ACCCCTCGTGCCGAATTCCCGGCCGCCCTAAGGGAGTCCGATTACAAAATCCTGACCGGT CACTAAACCAGCTCTGCTATATAGACCTCCAACCGACCACCTTACCGGCCATTTGCGTAA CGGGGCGGGGGTATACCACATTNTGGAAGTCCCGTTATTTTGTGCCAAACAACTCCCCTG ACCCAATGGGGGGAAACTTGAAATCCCCGGAGGTAACGCTTTCCGCCCTTGGGGCCTGCA AACCGCTACCCGGAATAACAGACAACCCAAATTCTGCCATAGAAACCCGAAGGCTGTCTG CCTAAGCCCCCGGCCTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005532 |
| Insert Size | 700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005532.3, NP_005523.3 |
| RefSeq Size | 656 bp |
| RefSeq ORF | 360 bp |
| Locus ID | 3429 |
| UniProt ID | P40305 |
| Protein Families | Transmembrane |
| Gene Summary | Probable adapter protein involved in different biological processes (PubMed:22427340, PubMed:27194766). Part of the signaling pathways that lead to apoptosis (PubMed:18330707, PubMed:27673746, PubMed:24970806). Involved in type-I interferon-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9 (PubMed:18330707, PubMed:27673746). Also functions in TNFSF10-induced apoptosis (PubMed:24970806). May also have a function in the nucleus, where it may be involved in the interferon-induced negative regulation of the transcriptional activity of NR4A1, NR4A2 and NR4A3 through the enhancement of XPO1-mediated nuclear export of these nuclear receptors (PubMed:22427340). May thereby play a role in the vascular response to injury (By similarity). In the innate immune response, has an antiviral activity towards hepatitis C virus/HCV (PubMed:27194766, PubMed:27777077). May prevent the replication of the virus by recruiting both the hepatitis C virus non-structural protein 5A/NS5A and the ubiquitination machinery via SKP2, promoting the ubiquitin-mediated proteasomal degradation of NS5A (PubMed:27194766, PubMed:27777077).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) represents an alternate allele that lacks a 9-nt segment in the CDS, as compared to variant 1. The resulting isoform (2) lacks an internal 3 aa segment, as compared to isoform 1. This variant represents a second allele commonly found in the human population. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201952 | IFI27 (Myc-DDK-tagged)-Human interferon, alpha-inducible protein 27 (IFI27), transcript variant 2 |
CNY 1200.00 |
|
| RC201952L1 | Lenti ORF clone of Human interferon, alpha-inducible protein 27 (IFI27), transcript variant 2, Myc-DDK-tagged |
CNY 3600.00 |
|
| RC201952L2 | Lenti ORF clone of Human interferon, alpha-inducible protein 27 (IFI27), transcript variant 2, mGFP tagged |
CNY 5890.00 |
|
| RC201952L3 | Lenti ORF clone of Human interferon, alpha-inducible protein 27 (IFI27), transcript variant 2, Myc-DDK-tagged |
CNY 3600.00 |
|
| RC201952L4 | Lenti ORF clone of Human interferon, alpha-inducible protein 27 (IFI27), transcript variant 2, mGFP tagged |
CNY 3600.00 |
|
| RG201952 | IFI27 (tGFP-tagged) - Human interferon, alpha-inducible protein 27 (IFI27), transcript variant 2 |
CNY 2800.00 |
